SU-E-T-519: Experimental Evaluation of Deterministic Acuros XB Radiation Transport Algorithm for Heterogeneity Dose Calculation Using the Radiological Physics Center's Lung Phantom

2012 ◽  
Vol 39 (6Part18) ◽  
pp. 3825-3825
Author(s):  
T Han ◽  
F Mourtada ◽  
R Repchak ◽  
J Tonigan ◽  
J Mikell ◽  
...  
2013 ◽  
Vol 40 (5) ◽  
pp. 051710 ◽  
Author(s):  
Tao Han ◽  
David Followill ◽  
Justin Mikell ◽  
Roman Repchak ◽  
Andrea Molineu ◽  
...  

2018 ◽  
Vol 18 (1) ◽  
pp. 75-81 ◽  
Author(s):  
Ashfaq Zaman ◽  
Muhammad Basim Kakakhel ◽  
Amjad Hussain

AbstractBackgroundA comparison of anisotropic analytical algorithm (AAA) and Acuros XB (AXB) dose calculation algorithms with Electron Gamma Shower (EGSnrc) Monte Carlo (MC) for modelling lung and bone heterogeneities encountered during enhanced dynamic wedged (EDWs) radiotherapy dose deliveries was carried out.Materials and methodsIn three heterogenous slab phantoms: water–bone, lung–bone and bone–lung, wedged percentage depth doses with EGSnrc, AAA and AXB algorithms for 6 MV photons for various field sizes (5×5, 10×10 and 20×20 cm2) and EDW angles (15°, 30°, 45° and 60°) have been scored.ResultsFor all the scenarios, AAA and AXB results were within ±1% of the MC in the pre-inhomogeneity region. For water–bone AAA and AXB deviated by 6 and 1%, respectively. For lung–bone an underestimation in lung (AAA: 5%, AXB: 2%) and overestimation in bone was observed (AAA: 13%, AXB: 4%). For bone–lung phantom overestimation in bone (AAA: 7%, AXB: 1%), a lung underdosage (AAA: 8%, AXB: 5%) was found. Post bone up to 12% difference in the AAA and MC results was observed as opposed to 6% in case of AXB.ConclusionThis study demonstrated the limitation of the AAA (in certain scenarios) and accuracy of AXB for dose estimation inside and around lung and bone inhomogeneities. The dose perturbation effects were found to be slightly dependent on the field size with no obvious EDW dependence.


2011 ◽  
Vol 51 (3) ◽  
pp. 376-385 ◽  
Author(s):  
Lone Hoffmann ◽  
Mai-Britt K. Jørgensen ◽  
Ludvig P. Muren ◽  
Jørgen B. B. Petersen

2018 ◽  
Vol 45 (8) ◽  
pp. 3909-3915 ◽  
Author(s):  
Lone Hoffmann ◽  
Markus Alber ◽  
Matthias Söhn ◽  
Ulrik Vindelev Elstrøm

2013 ◽  
Vol 40 (6Part19) ◽  
pp. 335-335 ◽  
Author(s):  
L Majithia ◽  
D DiCostanzo ◽  
M Weldon ◽  
N Gupta ◽  
Y Rong

2019 ◽  
Vol 20 (12) ◽  
pp. 127-137 ◽  
Author(s):  
Andries N. Schreuder ◽  
Daniel S. Bridges ◽  
Lauren Rigsby ◽  
Marc Blakey ◽  
Martin Janson ◽  
...  

2016 ◽  
Vol 43 (10) ◽  
pp. 5685-5694 ◽  
Author(s):  
Antonella Fogliata ◽  
Francesca Lobefalo ◽  
Giacomo Reggiori ◽  
Antonella Stravato ◽  
Stefano Tomatis ◽  
...  

Author(s):  
Ю. Кураченко ◽  
Yu. Kurachenko ◽  
Н. Санжарова ◽  
N. Sanzharova ◽  
Г. Козьмин ◽  
...  

Purpose: This work aims first to improve the reliability of absorbed dose calculation in critical organs of cattle during internal irradiation immediately after radiation accidents by a) improving the compartmental model of radionuclide metabolism in animal body; b) the use of precision computing technologies for modeling as the domain, and the actual radiation transport. In addition, the aim of the work is to determine the agreed values of the 131I critical dose in the cattle thyroid, leading to serious gland dysfunction and its follow-up destruction. Material and methods: To achieve aforecited goals, comprehensive studies were carried out to specify the parameters of the compartmental model, based on reliable experimental and theoretical data. Voxel technologies were applied for modeling the subject domain (thyroid gland and its environment). Finally, to solve the 131I radiation transport equation, the Monte Carlo code was applied, which takes into account the contribution of gamma and beta radiation source, and the contribution of the entire chain of secondary radiations in the dose calculation, up to the total energy dissipation. Results: As the main theoretical result, it is necessary to emphasize the conversion factor from the 131I activity, distributed uniformly in volume of the thyroid gland, to the average dose rate in the gland (Bq × Gy/s). This factor was calculated for both cows and calves in the selected domain configuration and thyroid morphology. The main practical result is a reliable estimation the lower bound of the absorbed dose in the thyroid, which in a short time leads to its destruction under internal 131I irradiation: ~300 Gy. Conclusion: Usage a compartmental model of the 131I metabolism with biokinetic parameters, received on the basis of reliable experimental data, and precise models of both the subject area and radiation transport for evaluation the dose in the cattle thyroid after the radiation accident allowed to obtain reliable values of the thyroid dose, adducting to its destruction at short notice.


2012 ◽  
Vol 39 (7Part1) ◽  
pp. 4104-4114 ◽  
Author(s):  
Yusuke Egashira ◽  
Teiji Nishio ◽  
Taeko Matsuura ◽  
Satoru Kameoka ◽  
Mitsuru Uesaka

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