MO-D-220-08: Quantitative Embryonic Central Nervous System Imaging Using High- Frequency Annular Arrays

2011 ◽  
Vol 38 (6Part26) ◽  
pp. 3718-3719
Author(s):  
JA Ketterling ◽  
O Aristizabal ◽  
J Mamou ◽  
E Filoux
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
High Frequency ◽  
Annular Arrays

Brainstem manifestations in neuromyelitis optica: a multicenter study of 258 patients

2013 ◽  
Vol 20 (7) ◽  
pp. 843-847 ◽  
Author(s):  
L Kremer ◽  
M Mealy ◽  
A Jacob ◽  
I Nakashima ◽  
P Cabre ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Central Nervous System ◽  
Nervous System ◽  
Hearing Loss ◽  
Neuromyelitis Optica ◽  
Multicenter Study ◽  
High Frequency ◽  
Caucasian Population ◽  
The Central Nervous System ◽  
Optic Nerve Involvement

Background: Neuromyelitis optica (NMO) is a severe autoimmune disease of the central nervous system characterized by spinal cord and optic nerve involvement. Brainstem manifestations have recently been described. Objective: To evaluate the time of occurrence, the frequency and the characteristics of brainstem symptoms in a cohort of patients with NMO according to the ethnic background and the serologic status for anti-aquaporin-4 antibodies (AQP4-abs). Methods: We performed a multicenter study of 258 patients with NMO according to the 2006 Wingerchuk criteria and we evaluated prospectively the frequency, the date of onset and the duration of various brainstem signs in this population. Results: Brainstem signs were observed in 81 patients (31.4%). The most frequently observed signs were vomiting (33.1%), hiccups (22.3%), oculomotor dysfunction (19.8%), pruritus (12.4%), followed by hearing loss (2.5%), facial palsy (2.5%), vertigo or vestibular ataxia (1.7%), trigeminal neuralgia (2.5%) and other cranial nerve signs (3.3%). They were inaugural in 44 patients (54.3%). The prevalence was higher in the non-Caucasian population (36.6%) than in the Caucasian population (26%) ( p<0.05) and was higher in AQP4-ab-seropositive patients (32.7%) than in seronegative patients (26%) (not significant). Conclusions: This study confirms the high frequency of brainstem symptoms in NMO with a majority of vomiting and hiccups. The prevalence of these manifestations was higher in the non Caucasian population.

Oxidative stress effects on the central nervous system of rats after acute exposure to ultra high frequency electromagnetic fields

2006 ◽  
Vol 27 (6) ◽  
pp. 487-493 ◽  
Author(s):  
Amâncio R. Ferreira ◽  
Fernanda Bonatto ◽  
Matheus Augusto de Bittencourt Pasquali ◽  
Manuela Polydoro ◽  
Felipe Dal-Pizzol ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Central Nervous System ◽  
Nervous System ◽  
Electromagnetic Fields ◽  
High Frequency ◽  
Acute Exposure ◽  
Ultra High Frequency ◽  
Stress Effects ◽  
The Central Nervous System

Neurons with High-Frequency Discharge in the Central Nervous System in Chronic Pain

1994 ◽  
Vol 62 (1-4) ◽  
pp. 290-294 ◽  
Author(s):  
K. Yamashiro ◽  
J. Mukawa ◽  
Y. Terada ◽  
N. Tomiyama ◽  
A. Ishida ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Chronic Pain ◽  
Nervous System ◽  
High Frequency ◽  
High Frequency Discharge ◽  
The Central Nervous System

scholarly journals The features of summary background electric activity of the hypothalamus of rats under conditions of chronic caffeine alimentation

2018 ◽  
Vol 9 (3) ◽  
pp. 417-425 ◽  
Author(s):  
T. G. Turitskaya ◽  
S. N. Lukashev ◽  
V. P. Lyashenko ◽  
G. G. Sidorenko
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
High Frequency ◽  
White Male ◽  
Posterior Hypothalamus ◽  
Male Rats ◽  
Neuronal System ◽  
Rat Hypothalamus ◽  
The Central Nervous System ◽  
Chronic Caffeine

One of the factors of the environment which essentially shifts homeostasis is diets which contain caffeine. The aim of the study was to find out the basic characteristics of background electrical activity of trophotrophic and ergotrophic zones of the hypothalamus in conditions of chronic caffeine alimentation. Experiments were carried out on non-linear white male rats. The first group consisted of control animals (n = 22). The second group (n = 24) was represented by the animals that were given pure caffeine in an amount of 150 mg/kg/day with their meal. The registration on a electrohypothalamogram was carried out in conditions of acute experiment, every 2 weeks for 12 weeks. The spectral (mkV2) and the normalized power (%) of electrohypothalamogram waves were analyzed within the common frequency band. The analysis of the results allowed us to establish a certain specificity of the reaction of the neuronal system of the trophotropic and ergotropic zones of the rat hypothalamus to the effect of chronic caffeine alimentation. The main difference in the reactive state of electrophysiological indices in the trophotrophic zone of rats is the lack of a typical desynchronization from the 4th to the 8th week of the study and the hypersynchronization after 12 weeks of the experiment. The most probable mechanism that explains the results obtained is the ultra-powerful GABA-ergic modulation of this zone, the main energy-accumulating center. Perhaps, this powerful inhibitory resource in this cerebral locus is the main stress-limiting factor that makes this zone of the central nervous system of rats less sensitive to caffeine exposure. Instead, under the influence of chronic caffeine load in the ergotropic zone of the hypothalamus, after 6 weeks of the experiment desynchronous high-frequency rhythms dominated. During the subsequent time of the experiment, we observed a decrease in both low-frequency and high-frequency components of the electrohypothalamogram of this zone. This gives reason to assume that the key component of the neurophysiological response of the posterior hypothalamus of rats to the caffeine ration is the powerful glutamatergic effects on the pre-synaptic and post-synaptic neurons under conditions of reactive exhaustion of local neurosynthetics. Caffeine depletion of the hypothalamic neurotransmission at the end of the experiment is replaced by an effective adaptive ergotropic restoration of neurosynthetic activity in this locus of the central nervous system of rats. Thus, caffeine has a powerful activating effect on the ergotropic function of the posterior hypothalamus of rats. Such a difference in the chronic effect of caffeine on the trophotropic and ergotropic zone of the rat hypothalamus is primarily due to the different mediator support of these zones underlying their physiological purpose. GABA is the main mediator of the trophotropic zone and the main neurotransmitter of its synchronous activity. At the same time, neurotransmitter support of the ergotropic zone is represented by glutamate, which, along with other agents, implements its desynchronous activity. Since caffeine stimulates excitation, activating the pathways traditionally associated with motivational and motor reactions in the brain, it can be assumed that this explains the fact of a more powerful influence of caffeine precisely on the ergotrophic zone of the hypothalamus.

Sign in / Sign up

Export Citation Format

Share Document