Poster - Thur Eve - 64: A Water Calorimetry-Based Dosimetry Standard for Direct Measurement of Absolute Absorbed Dose in Scanning Proton Beam Delivery

2010 ◽  
Vol 37 (7Part3) ◽  
pp. 3899-3899
Author(s):  
A Sarfehnia ◽  
B Clasie ◽  
E Chung ◽  
HM Lu ◽  
J Flanz ◽  
...  
2010 ◽  
Vol 37 (7Part1) ◽  
pp. 3541-3550 ◽  
Author(s):  
A. Sarfehnia ◽  
B. Clasie ◽  
E. Chung ◽  
H. M. Lu ◽  
J. Flanz ◽  
...  

Cancers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1889
Author(s):  
Arthur Bongrand ◽  
Charbel Koumeir ◽  
Daphnée Villoing ◽  
Arnaud Guertin ◽  
Ferid Haddad ◽  
...  

Proton therapy (PRT) is an irradiation technique that aims at limiting normal tissue damage while maintaining the tumor response. To study its specificities, the ARRONAX cyclotron is currently developing a preclinical structure compatible with biological experiments. A prerequisite is to identify and control uncertainties on the ARRONAX beamline, which can lead to significant biases in the observed biological results and dose–response relationships, as for any facility. This paper summarizes and quantifies the impact of uncertainty on proton range, absorbed dose, and dose homogeneity in a preclinical context of cell or small animal irradiation on the Bragg curve, using Monte Carlo simulations. All possible sources of uncertainty were investigated and discussed independently. Those with a significant impact were identified, and protocols were established to reduce their consequences. Overall, the uncertainties evaluated were similar to those from clinical practice and are considered compatible with the performance of radiobiological experiments, as well as the study of dose–response relationships on this proton beam. Another conclusion of this study is that Monte Carlo simulations can be used to help build preclinical lines in other setups.


2016 ◽  
Vol 32 (7) ◽  
pp. 932-937 ◽  
Author(s):  
Takahiro Yamada ◽  
Naoki Miyamoto ◽  
Taeko Matsuura ◽  
Seishin Takao ◽  
Yusuke Fujii ◽  
...  

2017 ◽  
Vol 123 ◽  
pp. S115
Author(s):  
M. Belosi ◽  
R. Van der Meer ◽  
P. Garcia de Acilu Laa ◽  
A. Bolsi ◽  
D. Weber ◽  
...  
Keyword(s):  

2011 ◽  
Vol 38 (6Part35) ◽  
pp. 3853-3853
Author(s):  
K Kraus ◽  
E Heath ◽  
U Oelfke

2013 ◽  
Vol 40 (6Part11) ◽  
pp. 212-212
Author(s):  
R Tosh ◽  
F Bateman ◽  
P Wong ◽  
N Baillie ◽  
B Athar ◽  
...  

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