Direct absorbed dose to water determination based on water calorimetry in scanning proton beam delivery

2010 ◽  
Vol 37 (7Part1) ◽  
pp. 3541-3550 ◽  
Author(s):  
A. Sarfehnia ◽  
B. Clasie ◽  
E. Chung ◽  
H. M. Lu ◽  
J. Flanz ◽  
...  
2013 ◽  
Vol 40 (6Part11) ◽  
pp. 212-212
Author(s):  
R Tosh ◽  
F Bateman ◽  
P Wong ◽  
N Baillie ◽  
B Athar ◽  
...  

2018 ◽  
Vol 41 (2) ◽  
pp. 227-235
Author(s):  
Kumaresh Chandra Paul ◽  
Guenther H Hartmann ◽  
Golam Abu Zakaria

Absorbed dose to water determination in the clinical practice introduces several perturbations factors in ionization chamber dosimetry. Displacement perturbation is one of them, which can be corrected by introducing the chamber-specific quality correction factor (kQ) or by introducing the concept of effective point of measurement (EPOM). The EPOM is the point in the chamber at which the measured dose would be the same as the measuring depth in absence of chamber. The aim of this study was to measure the displacement effect at cylindrical ionization chambers in 6 and 10 MV flat and true photon beams. The percentage of depth doses (PDDs) were considered for determining the shift of EPOM with respect to the well established Roos chamber. The displacement effect obtained a range of 0.25 to 0.57 times r (chamber radius) both in flat and true beams, which disagreed with the TRS-398 protocol recommended constant value of 0.6r.Journal of Bangladesh Academy of Sciences, Vol. 41, No. 2, 227-235, 2017


2010 ◽  
Vol 37 (7Part3) ◽  
pp. 3899-3899
Author(s):  
A Sarfehnia ◽  
B Clasie ◽  
E Chung ◽  
HM Lu ◽  
J Flanz ◽  
...  

Cancers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1889
Author(s):  
Arthur Bongrand ◽  
Charbel Koumeir ◽  
Daphnée Villoing ◽  
Arnaud Guertin ◽  
Ferid Haddad ◽  
...  

Proton therapy (PRT) is an irradiation technique that aims at limiting normal tissue damage while maintaining the tumor response. To study its specificities, the ARRONAX cyclotron is currently developing a preclinical structure compatible with biological experiments. A prerequisite is to identify and control uncertainties on the ARRONAX beamline, which can lead to significant biases in the observed biological results and dose–response relationships, as for any facility. This paper summarizes and quantifies the impact of uncertainty on proton range, absorbed dose, and dose homogeneity in a preclinical context of cell or small animal irradiation on the Bragg curve, using Monte Carlo simulations. All possible sources of uncertainty were investigated and discussed independently. Those with a significant impact were identified, and protocols were established to reduce their consequences. Overall, the uncertainties evaluated were similar to those from clinical practice and are considered compatible with the performance of radiobiological experiments, as well as the study of dose–response relationships on this proton beam. Another conclusion of this study is that Monte Carlo simulations can be used to help build preclinical lines in other setups.


Author(s):  
K. Hohlfeld ◽  
P. Andreo ◽  
O. Mattsson ◽  
J. P. Simoen

This report examines the methods by which absorbed dose to water can be determined for photon radiations with maximum energies from approximately 1 MeV to 50 MeV, the beam qualities most commonly used for radiation therapy. The report is primarily concerned with methods of measurement for photon radiation, but many aspects are also relevant to the dosimetry of other therapeutic beams (high-energy electrons, protons, etc.). It deals with methods that are sufficiently precise and well established to be incorporated into the dosimetric measurement chain as primary standards (i.e., methods based on ionisation, radiation-induced chemical changes, and calorimetry using either graphite or water). The report discusses the primary dose standards used in several national standards laboratories and reviews the international comparisons that have been made. The report also describes the reference conditions that are suitable for establishing primary standards and provides a formalism for determining absorbed dose, including a discussion of correction factors needed under conditions other than those used to calibrate an instrument at the standards laboratory.


2016 ◽  
Vol 43 (7) ◽  
pp. 4085-4092 ◽  
Author(s):  
S. Dufreneix ◽  
A. Ostrowsky ◽  
B. Rapp ◽  
J. Daures ◽  
J. M. Bordy

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