scholarly journals Monte Carlo simulations of absorbed dose in a mouse phantom from 18-fluorine compounds

2007 ◽  
Vol 34 (3) ◽  
pp. 1026-1036 ◽  
Author(s):  
Richard Taschereau ◽  
Arion F. Chatziioannou
Keyword(s):  
Monte Carlo ◽  
Monte Carlo Simulations ◽  
Absorbed Dose ◽  
Fluorine Compounds

scholarly journals A Monte Carlo Determination of Dose and Range Uncertainties for Preclinical Studies with a Proton Beam

Cancers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1889
Author(s):  
Arthur Bongrand ◽  
Charbel Koumeir ◽  
Daphnée Villoing ◽  
Arnaud Guertin ◽  
Ferid Haddad ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Monte Carlo Simulations ◽  
Proton Beam ◽  
Dose Response ◽  
Small Animal ◽  
Absorbed Dose ◽  
Normal Tissue Damage ◽  
Dose Homogeneity ◽  
And Control ◽  
The Impact

Proton therapy (PRT) is an irradiation technique that aims at limiting normal tissue damage while maintaining the tumor response. To study its specificities, the ARRONAX cyclotron is currently developing a preclinical structure compatible with biological experiments. A prerequisite is to identify and control uncertainties on the ARRONAX beamline, which can lead to significant biases in the observed biological results and dose–response relationships, as for any facility. This paper summarizes and quantifies the impact of uncertainty on proton range, absorbed dose, and dose homogeneity in a preclinical context of cell or small animal irradiation on the Bragg curve, using Monte Carlo simulations. All possible sources of uncertainty were investigated and discussed independently. Those with a significant impact were identified, and protocols were established to reduce their consequences. Overall, the uncertainties evaluated were similar to those from clinical practice and are considered compatible with the performance of radiobiological experiments, as well as the study of dose–response relationships on this proton beam. Another conclusion of this study is that Monte Carlo simulations can be used to help build preclinical lines in other setups.

3D Absorbed Dose Calculations Based on SPECT: Evaluation for 111-In/90-Y Therapy using Monte Carlo Simulations

2003 ◽  
Vol 18 (1) ◽  
pp. 99-107 ◽  
Author(s):  
Michael Ljungberg ◽  
Eric Frey ◽  
Katarina Sjögreen ◽  
Xiaowei Liu ◽  
Yuni Dewaraja ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Monte Carlo Simulations ◽  
Absorbed Dose ◽  
Dose Calculations

In vivo measurements for biokinetic and monte carlo simulations of absorbed dose in paediatric patients using radiopharmaceuticals

2016 ◽  
Vol 32 ◽  
pp. 229-230 ◽  
Author(s):  
J. Costa ◽  
P.Teles ◽  
R. Parafita ◽  
A. Canudo ◽  
D.C. Costa ◽  
...  
Keyword(s):  
Monte Carlo ◽  
Monte Carlo Simulations ◽  
Absorbed Dose ◽  
In Vivo Measurements ◽  
Paediatric Patients
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