Photonic logic gates with simultaneous processing of multiple signals

2012 ◽  
Author(s):  
Vasile Degeratu ◽  
Ştefania Degeratu ◽  
Paul Şchiopu
eLife ◽  
2018 ◽  
Vol 7 ◽  
Author(s):  
Yuchen Liu ◽  
Jianfa Li ◽  
Zhicong Chen ◽  
Weiren Huang ◽  
Zhiming Cai

Natural signaling circuits could be rewired to reprogram cells with pre-determined procedures. However, it is difficult to link cellular signals at will. Here, we describe signal-connectors—a series of RNA devices—that connect one signal to another signal at the translational level. We use them to either repress or enhance the translation of target genes in response to signals. Application of these devices allows us to construct various logic gates and to incorporate feedback loops into gene networks. They have also been used to rewire a native signaling pathway and even to create novel pathways. Furthermore, logical AND gates based on these devices and integration of multiple signals have been used successfully for identification and redirection of the state of cancer cells. Eventually, the malignant phenotypes of cancers have been reversed by rewiring the oncogenic signaling from promoting to suppressing tumorigenesis. We provide a novel platform for redirecting cellular information.


Research ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Mengjiao Pei ◽  
Changjin Wan ◽  
Qiong Chang ◽  
Jianhang Guo ◽  
Sai Jiang ◽  
...  

Associative learning is a critical learning principle uniting discrete ideas and percepts to improve individuals’ adaptability. However, enabling high tunability of the association processes as in biological counterparts and thus integration of multiple signals from the environment, ideally in a single device, is challenging. Here, we fabricate an organic ferroelectric neuromem capable of monadically implementing optically modulated associative learning. This approach couples the photogating effect at the interface with ferroelectric polarization switching, enabling highly tunable optical modulation of charge carriers. Our device acts as a smarter Pavlovian dog exhibiting adjustable associative learning with the training cycles tuned from thirteen to two. In particular, we obtain a large output difference (>103), which is very similar to the all-or-nothing biological sensory/motor neuron spiking with decrementless conduction. As proof-of-concept demonstrations, photoferroelectric coupling-based applications in cryptography and logic gates are achieved in a single device, indicating compatibility with biological and digital data processing.


2016 ◽  
Vol E99.C (2) ◽  
pp. 285-292 ◽  
Author(s):  
Tran THI THU HUONG ◽  
Hiroshi SHIMADA ◽  
Yoshinao MIZUGAKI

Author(s):  
Jiko Raut ◽  
Prithidipa Sahoo

Abstract:: Thiol-containing amino acids and peptides play crucial roles in many physiological processses. For example, Cysteine (Cys) and Homocysteine (Hcy) are considered to be related to a number of health disorders such as renal failure, AIDS, Alzheimer’s and Parkinson’s diseases, atherosclerotic cardiovascular diseases, neutral tube defects, and coronary heart disease. Glutathione (GSH), an important tripeptide with a thiol group, performs vital biological functions that are in-volved in combating oxidative stress and maintaining redox homeostasis. Cysteine also plays important roles in our bodies as an antioxidant, a metal cofactor binder in enzymes, and a protein structure stabilizer by disulfide bond formation in the proteins. Hcy are involved in cellular growth and GSH in redox homeostasis. Hence, the rapid, sensitive, and selective de-tection of such biothiols is of considerable importance and significant interest. Different fluorescent chemosensors have been introduced to develop and improve the detection techniques and accuracy of these biothiols. In this review article we have presented some research works to show a guiding principle for the design of effective chemosensors which are highly sensitive and selective for the detection of particular a group of biothiols in aqueous medium. In line with these develop-ments, the researchers have developed novel chemosensors that signal binding events of these above mentioned biothiols through their optical properties. The binding mechanism and properties have also been established with different theoretical studies. Their applications in the form of colorimetric kit, logic gates, live cell imaging, and quantification from different bi-ological samples have also been developed.


2020 ◽  
Vol 10 (4) ◽  
pp. 369-380
Author(s):  
K. Maji ◽  
K. Mukherjee ◽  
A. Raja

All optical tri-state frequency encoded logic gates NOT and NAND are proposed and numerically investigated using TOAD based interferometric switch for the first time to the best of our knowledge. The optical power spectrum, extinction ratio, contrast ration, and amplified spontaneous noise are calculated to analyze and confirm practical feasibility of the gates. The proposed device works for low switching energy and has high contrast and extinction ratio as indicated in this work.


Author(s):  
Alexey V. Kavokin ◽  
Jeremy J. Baumberg ◽  
Guillaume Malpuech ◽  
Fabrice P. Laussy

Polariton devices offer multiple advantages compared to conventional semiconductor devices. The bosonic nature of exciton polaritons offers opportunity of realisation of polariton lasers: coherent light sources based on bosonic condensates of polaritons. The final state stimulation of any transition feeding a polariton condensate has been used in many proposals such as for terahertz lasers based on polariton lasers. Furthermore, large coherence lengths of exciton-polaritons in microcavities open the way to realisation of polariton transport devices including transistors and logic gates. Being bosonic spin carriers, exciton-polaritons may be used in spintronic devices and polarisation switches. This chapter offers an overview on the existing proposals for polariton devices.


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