Fourier Transform Infrared (FTIR) Study of Thermal Stability in Vinylidene Fluoride Copolymers.

1985 ◽  
Author(s):  
S. K. Ahuja ◽  
S. Bailey Hiergesell ◽  
A. DeLuca ◽  
R. Finsterwalder ◽  
G. Scilla ◽  
...  
Keyword(s):  
Thermal Stability ◽  
Fourier Transform ◽  
Vinylidene Fluoride ◽  
Fourier Transform Infrared ◽  
Ftir Study

scholarly journals ONCE DAILY IMMEDIATE-AND EXTENDED-RELEASE BILAYER TABLETS OF ETORICOXIB: A STUDY ON THE RELEASE KINETICS

2019 ◽  
pp. 230-235
Author(s):  
BIBASWAN MISHRA ◽  
BISWARANJAN MOHANTY
Keyword(s):  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Fourier Transform Infrared Spectroscopy ◽  
Extended Release ◽  
Fourier Transform Infrared ◽  
Once Daily ◽  
N Value ◽  
Ftir Study ◽  
Bilayer Tablets ◽  
Bilayer Tablet

Objective: In the present work, the main objective was to develop bilayer extended release matrix tablets of etoricoxib by providing a loading dose followed by maintenance dose that expected to improve the therapeutic efficacy of the medication with less toxic effect. Methods: Bilayer tablets of etoricoxib was developed successfully with the meticulous proportion of release controlling Hydroxy propyl methyl cellulose K100 (HPMC K100) and lactose. The tablets were prepared by wet granulation technique. Granules for immediate layer and extended layer for different formulations were prepared separately. The formulations were developed and evaluations were performed to examine the parameters that affect the in vitro performance of the tablets. The drug-excipient compatibility was ensured by Fourier transform infrared spectroscopy (FTIR) study. Results: The values of physical parameters of all formulations were found within appreciable limit. Formulation containing HPMC K 100 and lactose in the proportion of 2:1 in the extended release layer was able to release 26.22% of drug in 15 min and shown a steady release of drug for an extended period of 12 h. The dissolution data was put in Korsemeyer–Peppas model in order to find out n value, which describes the drug release mechanism. The n-value of different formulations were found to be variable. The Fourier transform infrared spectroscopy (FTIR) study revealed absence of any other new peaks and also no differences in the positions of the absorption bands in the bilayer tablet F8 that indicate the lack of significant interactions between etoricoxib and other excipients. Conclusion: It had been concluded that once daily immediate-and extended release bilayer tablet of etoricoxib can be formulated with profound physical characteristics and dissolution properties. This resulted in reducing the daily dose and thus minimise the cardiovascular toxicity of etoricoxib.

Production and characterization of boron nitride-doped nanofiber mats created through electrospinning

2016 ◽  
Vol 47 (6) ◽  
pp. 993-1005 ◽  
Author(s):  
Yasemin Cakmak ◽  
M Fatih Canbolat ◽  
Enes Cakmak ◽  
Mehmet Dayik
Keyword(s):  
Thermal Stability ◽  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Thermogravimetric Analysis ◽  
Boron Nitride ◽  
Fourier Transform Infrared Spectroscopy ◽  
Fourier Transform Infrared ◽  
Electrospinning Method ◽  
The Fourier Transform ◽  
Nanofiber Mats

The aim of this study was to produce advanced nanofiber mats by adding boron nitride to poly (ɛ-caprolactone) polymer using an electrospinning method and to characterize the resultant structures. Pure poly (ɛ-caprolactone) nanofiber mats and boron nitride-doped nanofiber mats prepared at different concentrations were compared. The morphological structures of the nanofiber mats were examined under a scanning electron microscope, spectroscopic analyses were conducted using Fourier transform infrared spectroscopy, and thermal stability was analyzed using a thermogravimetric analysis method. Successful electrospinning of boron nitride-doped nanofibers at lower voltages was achieved. The thermogravimetric analysis test found that the thermal stability of boron nitride-doped nanofiber mats is higher than that of pure nanofibers, which suggests that the produced composite material could be preferable in applications involving insulation and high temperature. On the other hand, the Fourier transform infrared spectroscopy results indicated that no chemical reaction occurred between boron nitride and the poly (ɛ-caprolactone) nanofibers.

A Fourier Transform Infrared (FTIR) Study of the Reaction of Triethoxysilane (TES) and Bis[3-triethoxysilylpropyl]tetrasulfane (TESPT) with the Surface of Amorphous Silica

2004 ◽  
Vol 108 (11) ◽  
pp. 3563-3572 ◽  
Author(s):  
Michelle Marrone ◽  
Tania Montanari ◽  
Guido Busca ◽  
Lucia Conzatti ◽  
Giovanna Costa ◽  
...  
Keyword(s):  
Fourier Transform ◽  
Amorphous Silica ◽  
Fourier Transform Infrared ◽  
Ftir Study
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