Simultaneous depth-resolved imaging of sub-nanometer scale ossicular vibrations and morphological features of the human-cadaver middle ear with spectral-domain phase-sensitive optical coherence tomography

2012 ◽  
Author(s):  
Hrebesh M. Subhash ◽  
Anh Nguyen-Huynh ◽  
Ruikang K. Wang ◽  
Steven L. Jacques ◽  
Alfred L. Nuttall
Keyword(s):  
Optical Coherence Tomography ◽  
Middle Ear ◽  
Morphological Features ◽  
Spectral Domain ◽  
Nanometer Scale ◽  
Optical Coherence ◽  
Human Cadaver ◽  
Phase Sensitive ◽  
Domain Phase

scholarly journals Feasibility of spectral-domain phase-sensitive optical coherence tomography for middle ear vibrometry

2012 ◽  
Vol 17 (6) ◽  
pp. 060505 ◽  
Author(s):  
Hrebesh M. Subhash ◽  
Anh Nguyen-Huynh ◽  
Ruikang K. Wang ◽  
Steven L. Jacques ◽  
Niloy Choudhury ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Middle Ear ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Phase Sensitive ◽  
Domain Phase

scholarly journals Morphological Predictive Features on Spectral-Domain Optical Coherence Tomography for Visual Outcomes in Neovascular Age-Related Macular Degeneration Treated with Ranibizumab

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Georges Azar ◽  
Benjamin Wolff ◽  
Flore De Bats ◽  
Jeremie Halfon ◽  
Mate Streho ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Morphological Features ◽  
Age Related Macular Degeneration ◽  
Spectral Domain ◽  
Prognostic Indicators ◽  
Optical Coherence ◽  
Multicentric Study ◽  
Age Related ◽  
Sd Oct

Purpose. To identify spectral-domain optical coherence tomography (SD-OCT) predictive morphological features for the outcome of Ranibizumab therapy for neovascular age-related macular degeneration (AMD). Methods. This is a retrospective multicentric study that involved 64 eyes with naïve AMD. Patients who received three monthly intravitreal injections of Ranibizumab were stratified into (1) “responders” [≥ 5 letters gain on Early Treatment Diabetic Retinopathy Study (ETDRS) scale] and (2) “nonresponders” (< 5 letters gain). Best-corrected visual acuity (BCVA) and SD-OCT morphological features were compared at baseline and one month after three consecutive injections of Ranibizumab. Univariate and multivariate analyses were carried out to correlate these morphological features with the change in BCVA. Results. Among the 64 patients enrolled, 40 (62.5%) were “responders” and 24 (37.5%) “nonresponders”. Age, sex, and BCVA were comparable between both groups. A multivariate correlational analysis found that subfoveal choroidal thickness (SFCT) and the presence of pigment epithelial detachment (PED) > 250 μm at baseline were two independent prognostic indicators of final BCVA. No other SD-OCT morphological studied features seem to affect final BCVA after Ranibizumab treatment. Conclusion. SFCT and the presence of PED > 250 μm are two significant biomarkers that may predict improvement after Ranibizumab therapy for AMD. These markers may guide ophthalmologists' treatment decision under financial constraints and limited time.

Use of common path phase sensitive spectral domain optical coherence tomography for refractive index measurements

2011 ◽  
Vol 50 (25) ◽  
pp. E7 ◽  
Author(s):  
Yogesh Verma ◽  
Purnananda Nandi ◽  
K. Divakar Rao ◽  
Mrinalini Sharma ◽  
Pradeep Kumar Gupta
Keyword(s):  
Optical Coherence Tomography ◽  
Refractive Index ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Common Path ◽  
Phase Sensitive

Monitoring small changes in blood hematocrit using phase sensitive spectral domain optical coherence tomography

2010 ◽  
Author(s):  
Venu G. R. Manne ◽  
Ravi Kiran Manapuram ◽  
Narendran Sudheendran ◽  
Kirill V. Larin
Keyword(s):  
Optical Coherence Tomography ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Phase Sensitive
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