Depth-dependent displacement sensitivity analysis and the influence of Doppler angle for quantitative assessment of mechanical properties using phase-sensitive spectral domain optical coherence tomography

2016 ◽  
Author(s):  
Gillian Lynch ◽  
Hrebesh Subhash ◽  
Sergey Alexandrov ◽  
Martin Leahy
Keyword(s):  
Mechanical Properties ◽  
Sensitivity Analysis ◽  
Optical Coherence Tomography ◽  
Quantitative Assessment ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Doppler Angle ◽  
Displacement Sensitivity ◽  
Phase Sensitive

Use of common path phase sensitive spectral domain optical coherence tomography for refractive index measurements

2011 ◽  
Vol 50 (25) ◽  
pp. E7 ◽  
Author(s):  
Yogesh Verma ◽  
Purnananda Nandi ◽  
K. Divakar Rao ◽  
Mrinalini Sharma ◽  
Pradeep Kumar Gupta
Keyword(s):  
Optical Coherence Tomography ◽  
Refractive Index ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Common Path ◽  
Phase Sensitive

Monitoring small changes in blood hematocrit using phase sensitive spectral domain optical coherence tomography

2010 ◽  
Author(s):  
Venu G. R. Manne ◽  
Ravi Kiran Manapuram ◽  
Narendran Sudheendran ◽  
Kirill V. Larin
Keyword(s):  
Optical Coherence Tomography ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Phase Sensitive

scholarly journals Feasibility of spectral-domain phase-sensitive optical coherence tomography for middle ear vibrometry

2012 ◽  
Vol 17 (6) ◽  
pp. 060505 ◽  
Author(s):  
Hrebesh M. Subhash ◽  
Anh Nguyen-Huynh ◽  
Ruikang K. Wang ◽  
Steven L. Jacques ◽  
Niloy Choudhury ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Middle Ear ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Phase Sensitive ◽  
Domain Phase

scholarly journals Determining elastic properties of skin by measuring surface waves from an impulse mechanical stimulus using phase-sensitive optical coherence tomography

2011 ◽  
Vol 9 (70) ◽  
pp. 831-841 ◽  
Author(s):  
Chunhui Li ◽  
Guangying Guan ◽  
Roberto Reif ◽  
Zhihong Huang ◽  
Ruikang K. Wang
Keyword(s):  
Mechanical Properties ◽  
Optical Coherence Tomography ◽  
Surface Wave ◽  
Surface Waves ◽  
Disease Diagnosis ◽  
Optical Coherence ◽  
Measuring Surface ◽  
Phase Velocity Dispersion ◽  
Phase Sensitive

The mechanical properties of skin are important tissue parameters that are useful for understanding skin patho-physiology, which can aid disease diagnosis and treatment. This paper presents an innovative method that employs phase-sensitive spectral-domain optical coherence tomography (PhS-OCT) to characterize the biomechanical properties of skin by measuring surface waves induced by short impulses from a home-made shaker. Experiments are carried out on single and double-layer agar–agar phantoms, of different concentrations and thickness, and on in vivo human skin, at the forearm and the palm. For each experiment, the surface wave phase-velocity dispersion curves were calculated, from which the elasticity of each layer of the sample was determined. It is demonstrated that the experimental results agree well with previous work. This study provides a novel combination of PhS-OCT technology with a simple and an inexpensive mechanical impulse surface wave stimulation that can be used to non-invasively evaluate the mechanical properties of skin in vivo , and may offer potential use in clinical situations.

Sign in / Sign up

Export Citation Format

Share Document