Magnetic resonance thermometry for monitoring photothermal effects of interstitial laser irradiation

2012 ◽  
Author(s):  
Jessica Goddard ◽  
Jessnie Jose ◽  
Daniel Figueroa ◽  
Kelvin Le ◽  
Hong Liu ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Laser Irradiation ◽  
Magnetic Resonance Thermometry ◽  
Interstitial Laser ◽  
Photothermal Effects

scholarly journals Magnetic resonance thermometry using a GdIII-based contrast agent

2021 ◽  
Vol 57 (14) ◽  
pp. 1770-1773
Author(s):  
S. A. Amali S. Subasinghe ◽  
Jonathan Romero ◽  
Cassandra L. Ward ◽  
Matthew D. Bailey ◽  
Donna R. Zehner ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agent ◽  
Contrast Agents ◽  
Resonance Imaging ◽  
Magnetic Resonance Thermometry

The complexes described here serve as contrast agents for magnetic resonance imaging thermometry.

A printed Yagi–Uda antenna for application in magnetic resonance thermometry guided microwave hyperthermia applicators

2017 ◽  
Vol 62 (5) ◽  
pp. 1831-1847 ◽  
Author(s):  
M M Paulides ◽  
R M C Mestrom ◽  
G Salim ◽  
B B Adela ◽  
W C M Numan ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Thermometry ◽  
Microwave Hyperthermia

scholarly journals Magnetic Resonance Thermometry at 7T for Real-Time Monitoring and Correction of Ultrasound Induced Mild Hyperthermia

PLoS ONE ◽  
2012 ◽  
Vol 7 (4) ◽  
pp. e35509 ◽  
Author(s):  
Brett Z. Fite ◽  
Yu Liu ◽  
Dustin E. Kruse ◽  
Charles F. Caskey ◽  
Jeffrey H. Walton ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Real Time ◽  
Real Time Monitoring ◽  
Mild Hyperthermia ◽  
Magnetic Resonance Thermometry

Polydopamine may be easily functionalized with a range of nanomaterials for synergistic cancer therapy, in addition to its exceptional photothermal effects

2021 ◽  
Author(s):  
Moataz Dowaidar
Keyword(s):  
Magnetic Resonance ◽  
Cancer Therapy ◽  
Cancer Treatment ◽  
Large Scale ◽  
Diagnosis And Treatment ◽  
Self Healing ◽  
Adhesive Properties ◽  
Uniform Size ◽  
Photothermal Treatment ◽  
Photothermal Effects

This review carefully reviewed recent polydopamine (PDA) research, including targeted therapy and cancer synergistic medications. Recent breakthroughs in photothermal treatment coupled with complex therapies such as gene therapy, radiation, and especially immunotherapy were highlighted. Due to their exceptional biocompatibility, degradability, low toxicity and high photothermal conversion efficiency, facile oxidative self-polymerization of dopamine can create PDA and serve as an excellent nanocarrier or photothermal cancer treatment agent. Due to its high adhesive capacity, PDA may be easily functionalized with a range of nanomaterials for synergistic cancer therapy, in addition to its exceptional photothermal effects. Although PDA-based multifunctional nanoplatforms have gained interest for synergistic cancer therapy, such as chemo-photothermal treatment and photodynamic-photothermal treatment, discovering novel uses for PDA remains tough. First, despite its easy and mild process of synthesis, large-scale synthesis with uniform size and thickness is challenging owing to the absence of consistent quality control standards. Second, due to the strong adhesive properties of PDA, multifunctional nanoplatforms are prone to aggregating in a solution. Third, to improve PDA's clinical application, its safety should be fully researched. Before being deployed in clinical settings, PDA-based multifunctional systems need additional research. A PDA-based multifunctional platform for better synergistic cancer treatment is a forward-looking strategy. In particular, PDA-based immunotherapy systems will remain a research center.Besides immunotherapy, in recent years, the integration of cancer diagnosis and treatment has gained a lot of publicity. Polyphenols have been proven to suppress tumor development and interact with metals such as Fe3+, Pt4+, Cu2+, etc (MPNs). MPNs are biocompatible, functional, pH-responsive and can escape endosomes. PDA has the potential to develop MPNs with contrasting magnetic resonance agents like gadolinium due to the enormous quantity of catechol groups on its surface, allowing magnetic resonance imaging. Polyphenols also have tumor-inhibiting effects, and PDA's photothermal activity can ablate tumors. Consequently, PDA-based MPNs might be a promising way to integrate diagnosis and treatment. Moreover, polydopamine can crosslink acrylamide and other polymers to form anticancer and antibacterial hydrogels. Increasing the stickiness of polydopamine hydrogels is now underway, paving the path for self-adhesive bioelectronics hydrogels. Bioelectron self-adhesion and other capabilities such as self-healing, transparency, and bacterio-toxicity may be supplied to polydopamine hydrogels by altering phenolquinone's redox process. A prospective future trend is using self-adhesive polydopamine hydrogels with current bioelectronic materials. We think that polydopamine hydrogels will eventually advance from skin patches to implantable integrated bioelectronics.

Interstitial Laser Irradiation for Bladder Cancer

1986 ◽  
pp. 524-526
Author(s):  
H. Washida ◽  
M. Tsugaya ◽  
N. Nirao ◽  
H. Sakagami ◽  
Y. Iwase ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Laser Irradiation ◽  
Interstitial Laser

Magnetic Resonance Thermometry: An Emerging Three-Dimensional Temperature Diagnostic Technique

2019 ◽  
Author(s):  
Michael J. Benson ◽  
Mattias Cooper ◽  
Bret P. Van Poppel ◽  
Christopher J. Elkins
Keyword(s):  
Temperature Field ◽  
Data Analysis ◽  
Magnetic Resonance ◽  
Data Processing ◽  
Water Channel ◽  
Three Dimensional ◽  
Diagnostic Technique ◽  
The Other ◽  
Temperature Measurements ◽  
Magnetic Resonance Thermometry

Abstract Magnetic Resonance Thermometry (MRT) is a developing diagnostic technique that leverages advanced medical technologies to accurately measure the temperature of a fluid flow within and around complex geometries. The full three-dimensional temperature field obtained by MRT can be used to analyze heat transfer characteristics and potentially investigate thermal boundary layers near arbitrarily complex surfaces. This technique requires neither optical nor physical accessibility, thereby enabling a wide range of engineering applications. This paper describes the current state of the art for MRT measurement, detailing turbulent water channel tests, materials selection, scanning parameters, data analysis of time-averaged temperature measurements, and uncertainty estimates. The purpose of this work was to evaluate and refine the MRT technique to increase the accuracy of temperature measurements and minimize the error in fully turbulent flow measurements. In the present study, a plate with a vertical cylinder extending from both of its sides was placed between two channels, and a diagonal hole was drilled through the cylinder from one side of the plate to the other. This enabled fluid from one channel to mix with the fluid in the other. This experiment studied the mixing of two fluids at different temperatures. The upstream temperatures of each fluid were measured with thermocouples. Both flows were fully turbulent, and the colder temperature channel had a Reynolds number of 11,800. Tests were run with four different fluid temperatures for calibration and to determine any temperature dependence of measurements. Three-dimensional temperature field measurements are reported and details about data processing and procedures to conduct the experiments are provided. This work resulted in several notable improvements to MRT experimental methods. The test section and water channel were designed to limit the effects of thermal expansion in the stereolithography materials used for manufacturing the complex internal flow geometry. Multiple echo scans were used to minimize the effects of magnetic field drift commonly observed in extended scanning periods in MRI systems. Data analysis techniques were used to quantify expansion effects for both hot and cold flow cases. To quantify measurement uncertainty, the standard deviation of the mean was calculated at each data point across different scan numbers and confidence intervals established using a student t-test. An improved data processing code was used to filter data resulting in increased measurement accuracy and reduced uncertainty to less than 1 °C for most of the domain. Future work will further refine the experimental techniques to improve scanning procedures, employ high conductivity ceramics and larger geometries with relevant applications, and simplify data processing methods to generate full-field flow temperature data.

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