TU-EF-210-05: A Fast and Efficient Method for Determining Coagulation Temperatures of Tissue-Mimicking Thermal Therapy Gel Phantoms: Validated by Magnetic Resonance Thermometry

2015 ◽  
Vol 42 (6Part34) ◽  
pp. 3625-3625
Author(s):  
P Brodin ◽  
A Partanen ◽  
P Asp ◽  
C Branch ◽  
C Guha ◽  
...  
2017 ◽  
Vol 28 (4) ◽  
pp. 525-533 ◽  
Author(s):  
Danilo Silva ◽  
Mayur Sharma ◽  
Rupa Juthani ◽  
Antonio Meola ◽  
Gene H. Barnett

2021 ◽  
Vol 57 (14) ◽  
pp. 1770-1773
Author(s):  
S. A. Amali S. Subasinghe ◽  
Jonathan Romero ◽  
Cassandra L. Ward ◽  
Matthew D. Bailey ◽  
Donna R. Zehner ◽  
...  

The complexes described here serve as contrast agents for magnetic resonance imaging thermometry.


2017 ◽  
Vol 62 (5) ◽  
pp. 1831-1847 ◽  
Author(s):  
M M Paulides ◽  
R M C Mestrom ◽  
G Salim ◽  
B B Adela ◽  
W C M Numan ◽  
...  

2016 ◽  
Vol 13 (1) ◽  
pp. 15-22 ◽  
Author(s):  
David B. Comber ◽  
E. Bryn Pitt ◽  
Hunter B. Gilbert ◽  
Matthew W. Powelson ◽  
Emily Matijevich ◽  
...  

Abstract BACKGROUND: The recently developed magnetic resonance imaging–guided laser-induced thermal therapy offers a minimally invasive alternative to craniotomies performed for tumor resection or for amygdalohippocampectomy to control seizure disorders. Current laser-induced thermal therapies rely on linear stereotactic trajectories that mandate twist-drill entry into the skull and potentially long approaches traversing healthy brain. The use of robotically driven, telescoping, curved needles has the potential to reduce procedure invasiveness by tailoring trajectories to the curved shape of the ablated structure and by enabling access through natural orifices. OBJECTIVE: To investigate the feasibility of using a concentric tube robot to access the hippocampus through the foramen ovale to deliver thermal therapy and thereby provide a percutaneous treatment for epilepsy without drilling the skull. METHODS: The skull and both hippocampi were segmented from dual computed tomography/magnetic resonance image volumes for 10 patients. For each of the 20 hippocampi, a concentric tube robot was designed and optimized to traverse a trajectory from the foramen ovale to and through the hippocampus from head to tail. RESULTS: Across all 20 cases, the mean distances (errors) between the hippocampus medial axis and backbone of the needle were 0.55, 1.11, and 1.66 mm for the best, mean, and worst case, respectively. CONCLUSION: These curvilinear trajectories would provide accurate transforamenal delivery of an ablation probe to typical hippocampus volumes. This strategy has the potential both to decrease the invasiveness of the procedure and to increase the completeness of hippocampal ablation.


2021 ◽  
Author(s):  
Kelsey D Cobourn ◽  
Imazul Qadir ◽  
Islam Fayed ◽  
Hepzibha Alexander ◽  
Chima O Oluigbo

Abstract BACKGROUND Commercial magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) systems utilize a generalized Arrhenius model to estimate the area of tissue damage based on the power and time of ablation. However, the reliability of these estimates in Vivo remains unclear. OBJECTIVE To determine the accuracy and precision of the thermal damage estimate (TDE) calculated by commercially available MRgLITT systems using the generalized Arrhenius model. METHODS A single-center retrospective review of pediatric patients undergoing MRgLITT for lesional epilepsy was performed. The area of each lesion was measured on both TDE and intraoperative postablation, postcontrast T1 magnetic resonance images using ImageJ. Lesions requiring multiple ablations were excluded. The strength of the correlation between TDE and postlesioning measurements was assessed via linear regression. RESULTS A total of 32 lesions were identified in 19 patients. After exclusion, 13 pairs were available for analysis. Linear regression demonstrated a strong correlation between estimated and actual ablation areas (R2 = .97, P < .00001). The TDE underestimated the area of ablation by an average of 3.92% overall (standard error (SE) = 4.57%), but this varied depending on the type of pathologic tissue involved. TDE accuracy and precision were highest in tubers (n = 3), with average underestimation of 2.33% (SE = 0.33%). TDE underestimated the lesioning of the single hypothalamic hamartoma in our series by 52%. In periventricular nodular heterotopias, TDE overestimated ablation areas by an average of 13% (n = 2). CONCLUSION TDE reliability is variably consistent across tissue types, particularly in smaller or periventricular lesions. Further investigation is needed to understand the accuracy of this emerging minimally invasive technique.


PLoS ONE ◽  
2012 ◽  
Vol 7 (4) ◽  
pp. e35509 ◽  
Author(s):  
Brett Z. Fite ◽  
Yu Liu ◽  
Dustin E. Kruse ◽  
Charles F. Caskey ◽  
Jeffrey H. Walton ◽  
...  

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