Fat tissue histological study at NIR laser treatment of the skin in vivo

2011 ◽  
Author(s):  
Irina Y. Yanina ◽  
Valery V. Tuchin ◽  
Nikita A. Navolokin ◽  
Olga V. Matveeva ◽  
Alla B. Bucharskaya ◽  
...  
Author(s):  
Irina Yu. Yanina ◽  
Valery V. Tuchin ◽  
Nikita A. Navolokin ◽  
Olga V. Matveeva ◽  
Alla B. Bucharskaya ◽  
...  

2015 ◽  
Author(s):  
I. Y. Yanina ◽  
Yu. I. Svenskaya ◽  
N. A. Navolokin ◽  
O. V. Matveeva ◽  
A. B. Bucharskaya ◽  
...  

2012 ◽  
Vol 17 (5) ◽  
pp. 058002 ◽  
Author(s):  
Irina Yu. Yanina ◽  
Valery V. Tuchin ◽  
Nikita A. Navolokin ◽  
Olga V. Matveeva ◽  
Alla B. Bucharskaya ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-13 ◽  
Author(s):  
Karima Bensiameur-Touati ◽  
Ghouti Kacimi ◽  
El-Mehdi Haffaf ◽  
Sihem Berdja ◽  
Souhila Aouichat-Bouguerra

Context. Nigella sativa seeds are usually used as traditional medicine for a wide range of therapeutic purposes. Objective. To investigate the subacute toxicity of NS aqueous extract and select its lowest dose to study its antidiabetic effect. Methods. 5 AqE.NS doses (2, 6.4, 21, 33, and 60 g/Kg) were daily administered to mice by gavage. Biochemical parameters measurements and histological study of the liver and the kidney were performed after 6 weeks of supplementation. Thereafter, and after inducing diabetes by alloxan, rats were treated by 2 g/Kg of AqE.NS during 8 weeks. Metabolic parameters were measured on sera. A horizontal electrophoresis of plasmatic lipoprotein was conducted. Glycogen, total lipids, and triglycerides were measured in the liver. TBARS were evaluated on adipose tissue, liver, and pancreas. Results. AqE.NS showed no variation in urea and albumin at the 5 doses, but hepatotoxicity from 21 g/Kg was confirmed by histopathological observations of the liver. In diabetic rats, AqE.NS significantly decreased glycemia, TG, T-cholesterol, LDL-c, and TBARS and showed a restored insulinemia and a significant increase in HDL-c. Results on the liver indicated a decrease in lipids and a possible glycogenogenesis. Conclusion. AqE.NS showed its safety at low doses and its evident antihyperglycemic, antihyperlipidemic, and antioxidant effect.


Author(s):  
Xiaoming He ◽  
Shawn Mcgee ◽  
James E. Coad ◽  
Paul A. Iaizzo ◽  
David J. Swanlund ◽  
...  

In this paper, we report on the characterization of microwave therapy of normal porcine kidneys both in vitro and in vivo. This technology is being developed for eventual use in the treatment of small renal cell carcinoma (RCC) by minimally invasive procedures. During experiments, microwave energy was applied through an interstitial microwave probe (Urologix, Plymouth, MN) to the kidney cortex with occasional involvement of the kidney medulla. The thermal histories at several locations were recorded. After treatment, the kidneys were bisected and small tissue slices were cut out at approximately the same depth as the thermal probes. The tissue slices were further processed for histological study. Both cellular injury and the area of microvascular stasis were quantitatively evaluated by histology. Absolute rate kinetic models of cellular injury and vascular stasis were developed and fit to this data. A 3-D finite element thermal model based on the Pennes Bioheat equation was developed and solved using a commercial software package (ANSYS, V5.7). The Specific Absorption Rate (SAR) of the microwave probe was measured experimentally in tissue equivalent gel-like solution. The thermal model was first validated by the measured in vitro thermal histories. It was then used to determine the blood perfusion term in vivo.


2000 ◽  
Vol 88 (3) ◽  
pp. 881-887 ◽  
Author(s):  
Gale B. Carey

This study examined the influence of energy expenditure and energy intake on cellular mechanisms regulating adipose tissue metabolism. 1 Twenty-four swine were assigned to restricted-fed sedentary, restricted-fed exercise-trained, full-fed sedentary, or full-fed exercise-trained groups. After 3 mo of treatment, adipocytes were isolated and adipocyte size, adenosine A1 receptor characteristics, and lipolytic sensitivity were measured. Swine were infused with epinephrine during which adipose tissue extracellular adenosine, plasma fatty acids, and plasma glycerol were measured. Results revealed that adipocytes isolated from restricted-fed exercised swine had a smaller diameter, a lower number of A1 receptors, and a greater sensitivity to lipolytic stimulation, compared with adipocytes from full-fed exercised swine. Extracellular adenosine levels were transiently increased on infusion of epinephrine in adipose tissue of restricted-fed exercised but not full-fed exercised swine. These results suggest a role for adenosine in explaining the discrepancy between in vitro and in vivo lipolysis findings and underscore the notion that excess energy intake dampens the lipolytic sensitivity of adipocytes to β-agonists and adenosine, even if accompanied by exercise training.


2021 ◽  
Author(s):  
Jun Yang ◽  
Lin Sun ◽  
Shuhan Hui ◽  
Peng Zhang ◽  
Jian Li ◽  
...  

A new type of Ag@SnS2 was established with Ag decorated on SnS2 surface for improved photothermal conversion capability. Ag@SnS2 exhibited a robust in vitro antibacterial effect and in vivo wound disinfection under NIR laser irradiation.


1980 ◽  
Vol 26 (1) ◽  
pp. 66-68 ◽  
Author(s):  
C R Vogt ◽  
J C Liao ◽  
A Y Sun

Abstract We have developed a simple, sensitive, and accurate method for the determination of chloroform in rat blood, brain, kidney, liver, and fat. The detection limit is 2.5 ng of chloroform per gram of tissue. Studies of in vivo distribution of chloroform in rat blood and target tissues after intragastric intubation of chloroform/water show that the amount of chloroform accumulated in the different tissues increases with increasing doses. Fat tissue contains the greatest amount of chloroform. The accumulation of chloroform in rat blood and target tissues seems to be maximum 1.5 h after administration, and the apparent chloroform concentration is almost at baseline value 8 h later.


Sign in / Sign up

Export Citation Format

Share Document