Skeletonization approach for characterization of benign vs. malignant single thyroid nodules using 3D contrast enhanced ultrasound

2011 ◽  
Author(s):  
Filippo Molinari ◽  
Alice Mantovani ◽  
Maurilio Deandrea ◽  
Paolo Limone ◽  
Roberto Garberoglio ◽  
...  
Keyword(s):  
Thyroid Nodules ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced

Contrast-enhanced ultrasound characterization of the vascularity of the rotator cuff tendon: Age- and activity-related changes in the intact asymptomatic rotator cuff

2008 ◽  
Vol 17 (1) ◽  
pp. S96-S100 ◽  
Author(s):  
Jonas R. Rudzki ◽  
Ronald S. Adler ◽  
Russell F. Warren ◽  
Warren R. Kadrmas ◽  
Nikhail Verma ◽  
...  
Keyword(s):  
Rotator Cuff ◽  
Contrast Enhanced Ultrasound ◽  
Rotator Cuff Tendon ◽  
Contrast Enhanced

scholarly journals Diagnostic Value of Contrast-Enhanced Ultrasound Evaluation of Malignant and Benign Solitary Thyroid Nodules

2016 ◽  
Vol 70 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Pēteris Priedītis ◽  
Maija Radziņa ◽  
Ilze Štrumfa ◽  
Zenons Narbuts ◽  
Arturs Ozoliņs ◽  
...  
Keyword(s):  
Contrast Enhancement ◽  
Thyroid Nodules ◽  
Fine Needle Biopsy ◽  
Diagnostic Value ◽  
Contrast Enhanced Ultrasound ◽  
Clinical Value ◽  
Additional Tool ◽  
Ultrasound Evaluation ◽  
Contrast Enhanced ◽  
Benign Nodules

Abstract The aim of the study was to investigate the diagnostic value of contrast-enhanced ultrasound (CEUS) in differentiating benign and malignant thyroid nodules. Thirty-five patients with morphologically proved thyroid nodules (17 malignant; 18 benign), underwent CEUS examination. Five enhancement patterns were evaluated: vascularisation, homogeneity, presence of peripheral rim type enhancement, wash-out rate of the contrast medium, and enhancement using microvascular imaging application. Time-intensity curves (TIC) were analysed in post-processing and defined as three types: slow versus rapid and stable versus rapid biphasic wash-out. Diagnostic value of the listed CEUS parameters was calculated. The results showed medium strength correlation between morphology (benign versus malignant nodule) and type of TIC curve rs = 0.38 (p = 0.021), as well as between mode of contrast enhancement rs = 0.39 (p = 0.022) and wash-out pattern rs =0.39 (p = 0.024). The overall pooled sensitivity of selected diagnostic parameters was 82%, specificity 57%, and accuracy 70%. Malignant nodules were characterised by iso- or hypovascular contrast enhancement and slow wash-out, while benign nodules showed hypervascular enhancement with rapid wash-out TIC curve and rim-like pattern. The CEUS patterns significantly differed between malignant and benign thyroid nodules with high diagnostic accuracy. Thus, CEUS has important clinical value as an additional tool to ultrasound and fine needle biopsy.

Characterization of Single Thyroid Nodules by Contrast-Enhanced 3-D Ultrasound

2010 ◽  
Vol 36 (10) ◽  
pp. 1616-1625 ◽  
Author(s):  
Filippo Molinari ◽  
Alice Mantovani ◽  
Maurilio Deandrea ◽  
Paolo Limone ◽  
Roberto Garberoglio ◽  
...  
Keyword(s):  
Thyroid Nodules ◽  
Contrast Enhanced

scholarly journals Diagnostic Accuracy of Contrast-Enhanced Ultrasound Enhancement Patterns for Thyroid Nodules

2016 ◽  
Vol 22 ◽  
pp. 4755-4764 ◽  
Author(s):  
Yan Zhang ◽  
Yu-kun Luo ◽  
Ming-bo Zhang ◽  
Jie Li ◽  
Junlai Li ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Thyroid Nodules ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced ◽  
Ultrasound Enhancement

scholarly journals Exploring the Value of Radiomics Features Based on B-Mode and Contrast-Enhanced Ultrasound in Discriminating the Nature of Thyroid Nodules

2021 ◽  
Vol 11 ◽  
Author(s):  
Shi Yan Guo ◽  
Ping Zhou ◽  
Yan Zhang ◽  
Li Qing Jiang ◽  
Yong Feng Zhao
Keyword(s):  
Diagnostic Performance ◽  
Thyroid Nodules ◽  
New Technologies ◽  
Statistical Significance ◽  
Characteristic Curve ◽  
Logistic Models ◽  
Contrast Enhanced Ultrasound ◽  
Clinical Value ◽  
Contrast Enhanced ◽  
Significant Difference

BackgroundWith the improvement of ultrasound imaging resolution and the application of various new technologies, the detection rate of thyroid nodules has increased greatly in recent years. However, there are still challenges in accurately diagnosing the nature of thyroid nodules. This study aimed to evaluate the clinical application value of the radiomics features extracted from B-mode ultrasound (B-US) images combined with contrast-enhanced ultrasound (CEUS) images in the differentiation of benign and malignant thyroid nodules by comparing the diagnostic performance of four logistic models.MethodsWe retrospectively collected and ultimately included B-US images and CEUS images of 123 nodules from 123 patients, and then extracted the corresponding radiomics features from these images respectively. Meanwhile, a senior radiologist combined the thyroid imaging reporting and data system (TI-RADS) and the enhancement pattern of the ultrasonography to make a graded diagnosis of the malignancy of these nodules. Next, based on these radiomics features and grades, logistic regression was used to help build the models (B-US radiomics model, CEUS radiomics model, B-US+CEUS radiomics model, and TI-RADS+CEUS model). Finally, the study assessed the diagnostic performance of these radiomics features with a comparison of the area under the curve (AUC) of the receiver operating characteristic curve of four logistic models for predicting the benignity or malignancy of thyroid nodules.ResultsThe AUC in the differential diagnosis of the nature of thyroid nodules was 0.791 for the B-US radiomics model, 0.766 for the CEUS radiomics model, 0.861 for the B-US+CEUS radiomics model, and 0.785 for the TI-RADS+CEUS model. Compared to the TI-RADS+CEUS model, there was no statistical significance observed in AUC between the B-US radiomics model, CEUS radiomics model, B-US+CEUS radiomics model, and TI-RADS+CEUS model (P>0.05). However, a significant difference was observed between the single B-US radiomics model or CEUS radiomics model and B-US+CEUS radiomics model (P<0.05).ConclusionIn our study, the B-US radiomics model, CEUS radiomics model, and B-US+CEUS radiomics model demonstrated similar performance with the TI-RADS+CEUS model of senior radiologists in diagnosing the benignity or malignancy of thyroid nodules, while the B-US+CEUS radiomics model showed better diagnostic performance than single B-US radiomics model or CEUS radiomics model. It was proved that B-US radiomics features and CEUS radiomics features are of high clinical value as the combination of the two had better diagnostic performance.

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