Characterization of Early Hepatocellular Carcinoma and High‐Grade Dysplastic Nodules on Contrast‐Enhanced Ultrasound

2020 ◽  
Vol 39 (9) ◽  
pp. 1799-1808
Author(s):  
Pei‐li Fan ◽  
Han‐sheng Xia ◽  
Hong Ding ◽  
Yi Dong ◽  
Ling‐li Chen ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
High Grade ◽  
Contrast Enhanced Ultrasound ◽  
Early Hepatocellular Carcinoma ◽  
Dysplastic Nodules ◽  
Contrast Enhanced

Contrast-enhanced ultrasound features of hepatocellular carcinoma not detected during the screening procedure

2017 ◽  
Vol 55 (08) ◽  
pp. 748-753
Author(s):  
Yi Dong ◽  
Wen-Ping Wang ◽  
Feng Mao ◽  
Christoph Dietrich
Keyword(s):  
Magnetic Resonance Imaging ◽  
Hepatocellular Carcinoma ◽  
Magnetic Resonance ◽  
Screening Procedure ◽  
Arterial Phase ◽  
Contrast Enhanced Ultrasound ◽  
Resonance Imaging ◽  
Contrast Enhanced ◽  
Patients At Risk

Abstract Aim The aim of this retrospective study is to report on the characteristics of contrast-enhanced ultrasound (CEUS) of primarily not detected hepatocellular carcinoma (HCC) during the screening procedure of patients at risk. Methods Sixty-four patients with a finally solitary and histologically proven HCC not detected HCC during the screening procedure were retrospectively analyzed. Most of HCC lesions (90.6 %, 58/64) measured < 20 mm in diameter. All HCC lesions were not detected during the initial screening procedure but suspected using contrast-enhanced magnetic resonance imaging. The final gold standard was biopsy or surgery with histological examination. Results On CEUS, 62/64 (96.8 %) of HCC were characterized as an obviously hyperenhanced lesion in arterial phase, and 41/64 (64.1 %) of HCC were characterized as hypoenhancing lesions in the portal venous and late phases. During the arterial phase of CEUS, 96.8 % of HCC displayed homogeneous hyperenhancement. Knowing the CEUS and magnetic resonance imaging findings, 45/64 (70.3 %) could have been detected using B-mode ultrasound (BMUS). Conclusion BMUS as a screening procedure is generally accepted. Contrast-enhanced imaging modalities have improved detection and characterization of HCC. Homogeneous hyperenhancement during the arterial phase and mild washout are indicative for HCC in liver cirrhosis.

scholarly journals Contrast-Enhanced Ultrasound for the Characterization of Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma

Liver Cancer ◽  
2015 ◽  
Vol 4 (4) ◽  
pp. 241-252 ◽  
Author(s):  
Guang-Jian Liu ◽  
Wei Wang ◽  
Ming-De Lu ◽  
Xiao-Yan Xie ◽  
Hui-Xiong Xu ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Intrahepatic Cholangiocarcinoma ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced
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