Real-time co-registered ultrasound and photoacoustic imaging system based on FPGA and DSP architecture

2011 ◽  
Author(s):  
Umar Alqasemi ◽  
Hai Li ◽  
Andres Aguirre ◽  
Quing Zhu
Keyword(s):  
Real Time ◽  
Imaging System ◽  
Photoacoustic Imaging ◽  
Dsp Architecture

A pilot study of photoacoustic imaging system for improved real-time visualization of neurovascular bundle during radical prostatectomy

The Prostate ◽  
2015 ◽  
Vol 76 (3) ◽  
pp. 307-315 ◽  
Author(s):  
Akio Horiguchi ◽  
Kazuhiro Tsujita ◽  
Kaku Irisawa ◽  
Tadashi Kasamatsu ◽  
Kazuhiro Hirota ◽  
...  
Keyword(s):  
Pilot Study ◽  
Radical Prostatectomy ◽  
Real Time ◽  
Imaging System ◽  
Photoacoustic Imaging ◽  
Neurovascular Bundle ◽  
Real Time Visualization

scholarly journals Towards clinical photoacoustic and ultrasound imaging: Probe improvement and real-time graphical user interface

2020 ◽  
Vol 245 (4) ◽  
pp. 321-329 ◽  
Author(s):  
Jeesu Kim ◽  
Eun-Yeong Park ◽  
Byullee Park ◽  
Wonseok Choi ◽  
Ki J Lee ◽  
...  
Keyword(s):  
User Interface ◽  
Real Time ◽  
Ultrasound Imaging ◽  
Graphical User Interface ◽  
Imaging System ◽  
Photoacoustic Imaging ◽  
Clinical Applications ◽  
Imaging Systems ◽  
Imaging Probe ◽  
Conventional Ultrasound

Photoacoustic imaging is a non-invasive and non-ionizing biomedical technique that has been investigated widely for various clinical applications. By taking the advantages of conventional ultrasound imaging, hand-held operation with a linear array transducer should be favorable for successful clinical translation of photoacoustic imaging. In this paper, we present new key updates contributed to the previously developed real-time clinical photoacoustic and ultrasound imaging system for improving the clinical usability of the system. We developed a seamless image optimization platform, designed a real-time parameter control software with a user-friendly graphical user interface, performed Monte Carlo simulation of the optical fluence in the imaging plane, and optimized the geometry of the imaging probe. The updated system allows optimizing of all imaging parameters while continuously acquiring the photoacoustic and ultrasound images in real-time. The updated system has great potential to be used in a variety of clinical applications such as assessing the malignancy of thyroid cancer, breast cancer, and melanoma. Impact statement Photoacoustic imaging is a promising biomedical imaging modality that can visualize both structural and functional information of biological tissue. Because of its easiness to be integrated with conventional ultrasound imaging systems, numerous studies have been conducted to develop and apply clinical photoacoustic imaging systems. However, most of the systems were not suitable for general-purpose clinical applications due to one of the following reasons: target specific design, immobility, inaccessible operation sequence, and lack of hand-held operation. This study demonstrates a real-time clinical photoacoustic and ultrasound imaging system, which can overcome the limitations of the previous systems for successful clinical translation.

Development of Real-Time 3-D Photoacoustic Imaging System Employing Spherically Curved Array Transducer

2017 ◽  
Vol 64 (8) ◽  
pp. 1223-1233 ◽  
Author(s):  
Ryo Nagaoka ◽  
Takuya Tabata ◽  
Ryo Takagi ◽  
Shin Yoshizawa ◽  
Shin-Ichiro Umemura ◽  
...  
Keyword(s):  
Real Time ◽  
Imaging System ◽  
Photoacoustic Imaging ◽  
Array Transducer ◽  
Curved Array Transducer

Real-Time Photoacoustic Imaging System Based on Phase Contrast Demodulation

2016 ◽  
Vol 53 (7) ◽  
pp. 071701
Author(s):  
张宇 Zhang Yu ◽  
薛月菊 Xue Yueju ◽  
贾金亮 Jia Jinliang ◽  
金晓勇 Jin Xiaoyong ◽  
刘洪山 Liu Hongshan ◽  
...  
Keyword(s):  
Real Time ◽  
Phase Contrast ◽  
Imaging System ◽  
Photoacoustic Imaging

scholarly journals Real-time photoacoustic imaging system for burn diagnosis

2014 ◽  
Vol 19 (8) ◽  
pp. 086013 ◽  
Author(s):  
Taiichiro Ida ◽  
Yasushi Kawaguchi ◽  
Satoko Kawauchi ◽  
Keiichi Iwaya ◽  
Hitoshi Tsuda ◽  
...  
Keyword(s):  
Real Time ◽  
Imaging System ◽  
Photoacoustic Imaging

scholarly journals A Handheld Real-Time Photoacoustic Imaging System for Animal Neurological Disease Models: From Simulation to Realization

Sensors ◽  
2018 ◽  
Vol 18 (11) ◽  
pp. 4081 ◽  
Author(s):  
Yu-Hang Liu ◽  
Yu Xu ◽  
Lun-De Liao ◽  
Kim Chan ◽  
Nitish Thakor
Keyword(s):  
Real Time ◽  
Neurological Disease ◽  
Cerebral Blood Volume ◽  
Soft Tissues ◽  
Imaging System ◽  
Photoacoustic Imaging ◽  
Maximum Intensity Projection ◽  
Disease Models ◽  
Depth Information ◽  
Functional Impairments

This article provides a guide to design and build a handheld, real-time photoacoustic (PA) imaging system from simulation to realization for animal neurological disease models. A pulsed laser and array-based ultrasound (US) platform were utilized to develop the system for evaluating vascular functions in rats with focal ischemia or subcutaneous tumors. To optimize the laser light delivery, finite element (FE)-based simulation models were developed to provide information regarding light propagation and PA wave generation in soft tissues. Besides, simulations were also conducted to evaluate the ideal imaging resolution of the US system. As a result, a PA C-scan image of a designed phantom in 1% Lipofundin was reconstructed with depth information. Performance of the handheld PA system was tested in an animal ischemia model, which revealed that cerebral blood volume (CBV) changes at the cortical surface could be monitored immediately after ischemia induction. Another experiment on subcutaneous tumors showed the anomalous distribution of the total hemoglobin concentration (HbT) and oxygen saturation (SO2), while 3D and maximum intensity projection (MIP) PA images of the subcutaneous tumors are also presented in this article. Overall, this system shows promise for monitoring disease progression in vascular functional impairments.

scholarly journals Characterization of a Fiber Bundle-Based Real-Time Ultrasound/Photoacoustic Imaging System and Its In Vivo Functional Imaging Applications

Micromachines ◽  
2019 ◽  
Vol 10 (12) ◽  
pp. 820
Author(s):  
He Leng ◽  
Yuhling Wang ◽  
De-Fu Jhang ◽  
Tsung-Sheng Chu ◽  
Chia-Hui Tsao ◽  
...  
Keyword(s):  
User Interface ◽  
Real Time ◽  
In Vivo Imaging ◽  
Fiber Bundle ◽  
Imaging System ◽  
Structural Information ◽  
Photoacoustic Imaging ◽  
Numerical Aperture ◽  
Biological Tissues

Photoacoustic (PA) imaging is an attractive technology for imaging biological tissues because it can capture both functional and structural information with satisfactory spatial resolution. Current commercially available PA imaging systems are limited by their bulky size or inflexible user interface. We present a new handheld real-time ultrasound/photoacoustic imaging system (HARP) consisting of a detachable, high-numerical-aperture (NA) fiber bundle-based illumination system integrated with an array-based ultrasound (US) transducer and a data acquisition platform. In this system, different PA probes can be used for different imaging applications by switching the transducers and the corresponding jackets to combine the fiber pads and transducer into a single probe. The intuitive user interface is a completely programmable MATLAB-based platform. In vitro phantom experiments were conducted to test the imaging performance of the developed PA system. Furthermore, we demonstrated (1) in vivo brain vasculature imaging, (2) in vivo imaging of real-time stimulus-evoked cortical hemodynamic changes during forepaw electrical stimulation, and (3) in vivo imaging of real-time cerebral pharmacokinetics in rats using the developed PA system. The overall purpose of this design concept for a customizable US/PA imaging system is to help overcome the diverse challenges faced by medical researchers performing both preclinical and clinical PA studies.

A Photoacoustic Imaging System with Optimized Real-Time Parallel Reconstruction

2013 ◽  
Vol 30 (10) ◽  
pp. 100702
Author(s):  
Ting Feng ◽  
Jie Yuan ◽  
Yao Yu ◽  
Yu Zhou ◽  
Guan Xu
Keyword(s):  
Real Time ◽  
Imaging System ◽  
Photoacoustic Imaging ◽  
Parallel Reconstruction
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