Coherent detection of diffusely scattered light for extending depth using multiply scattered low coherence interferometry

2011 ◽  
Author(s):  
Michael Giacomelli ◽  
Adam Wax
Keyword(s):  
Scattered Light ◽  
Coherent Detection ◽  
Low Coherence ◽  
Low Coherence Interferometry

High angle phase modulated low coherence interferometry for path length resolved Doppler measurements of multiply scattered light

2008 ◽  
Vol 281 (3) ◽  
pp. 494-498 ◽  
Author(s):  
Babu Varghese ◽  
Vinayakrishnan Rajan ◽  
Ton G. Van Leeuwen ◽  
Wiendelt Steenbergen
Keyword(s):  
Path Length ◽  
Scattered Light ◽  
High Angle ◽  
Low Coherence ◽  
Low Coherence Interferometry

scholarly journals Nuclear Morphology Measurements with Angle-Resolved Low Coherence Interferometry For Application To Cell Biology And Early Cancer Detection

2011 ◽  
Vol 34 (5) ◽  
pp. 207-222 ◽  
Author(s):  
Adam Wax ◽  
Kevin J. Chalut
Keyword(s):  
Cell Biology ◽  
Cellular Structure ◽  
Structural Changes ◽  
Structural Information ◽  
Imaging Techniques ◽  
Scattered Light ◽  
Chemotherapeutic Agents ◽  
Low Coherence ◽  
Quantitative Measurements ◽  
Low Coherence Interferometry

The study of intact, living cells using non-invasive optical spectroscopic methods offers the opportunity to assess cellular structure and organization in a way that is not possible with commonly used cell biology imaging techniques. We have developed a novel spectroscopic technique for diagnosing disease at the cellular level based on using low-coherence interferometry (LCI) to detect the angular distribution of scattered light. Angle-resolved LCI (a/LCI) combines the ability of LCI to isolate scattering from sub-surface tissue layers with the ability of light scattering spectroscopy to obtain structural information on sub-wavelength scales. In application to examining cellular structure, a/LCI enables quantitative measurements of changes in the size and texture of cell nuclei. These quantitative measurements are characteristic of different pathological states. The capabilities of a/LCI were demonstrated using a clinical system that can be applied in endoscopic surveillance of esophageal tissue, producing high sensitivity and specificity for detecting dysplastic tissuesin vivo. Experiments within vitrocell samples also show the utility of a/LCI in observing structural changes due to environmental stimuli as well as detecting apoptosis due to chemotherapeutic agents.

Fringe-Distortion-Correction for Polarized Low-Coherence Interferometry With Phosphor-Based LED

2019 ◽  
Vol 37 (14) ◽  
pp. 3557-3562
Author(s):  
Rundong Wang ◽  
Shuang Wang ◽  
Junfeng Jiang ◽  
Kun Liu ◽  
Xue Wang ◽  
...  
Keyword(s):  
Distortion Correction ◽  
Low Coherence ◽  
Low Coherence Interferometry

Light source for low-coherence interferometry surface diagnostics

2011 ◽  
Author(s):  
Zdeněk Buchta ◽  
Bretislav Mikel ◽  
Simon Rerucha ◽  
Josef Lazar ◽  
Ondrej Cip
Keyword(s):  
Light Source ◽  
Low Coherence ◽  
Low Coherence Interferometry ◽  
Surface Diagnostics

scholarly journals Cellular Organization and Substructure Measured Using Angle-Resolved Low-Coherence Interferometry

2002 ◽  
Vol 82 (4) ◽  
pp. 2256-2264 ◽  
Author(s):  
Adam Wax ◽  
Changhuei Yang ◽  
Vadim Backman ◽  
Kamran Badizadegan ◽  
Charles W. Boone ◽  
...  
Keyword(s):  
Cellular Organization ◽  
Low Coherence ◽  
Low Coherence Interferometry

A wide angle low coherence interferometry based eye length optometer

2015 ◽  
Author(s):  
Alexander Meadway ◽  
John Siegwart ◽  
Christine Wildsoet ◽  
Thomas Norton ◽  
Yuhua Zhang
Keyword(s):  
Wide Angle ◽  
Low Coherence ◽  
Low Coherence Interferometry
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