Optochemical sensor based on screenprinted fluorescent sensorspots surrounded by organic photodiodes for multianalyte detection

2010 ◽  
Author(s):  
E. Kraker ◽  
B. Lamprecht ◽  
A. Haase ◽  
G. Jakopic ◽  
T. Abel ◽  
...  
Keyword(s):  
Multianalyte Detection ◽  
Optochemical Sensor

Simultaneous Multianalyte Detection with a Nanometer-Scale Pore

2001 ◽  
Vol 73 (10) ◽  
pp. 2268-2272 ◽  
Author(s):  
John J. Kasianowicz ◽  
Sarah E. Henrickson ◽  
Howard H. Weetall ◽  
Baldwin Robertson
Keyword(s):  
Nanometer Scale ◽  
Multianalyte Detection

Study of the performance of an optochemical sensor for ammonia

1996 ◽  
Vol 320 (2-3) ◽  
pp. 235-243 ◽  
Author(s):  
Martina Trinkel ◽  
Wolfgang Trettnak ◽  
Franz Reininger ◽  
Roman Benes ◽  
Paul O'Leary ◽  
...  
Keyword(s):  
Optochemical Sensor

Surface-plasmon-resonance-based array biosensors for multianalyte detection

1998 ◽  
Author(s):  
Michael J. O'Brien II ◽  
Victor H. Perez-Luna ◽  
Leonard M. Tender ◽  
Mark Edmunds ◽  
Ben Lascelles ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Multianalyte Detection

Novel color standards for digital color analysis of optochemical sensor arrays

Talanta ◽  
2019 ◽  
Vol 197 ◽  
pp. 638-644 ◽  
Author(s):  
Andrey V. Kalinichev ◽  
Nadezhda V. Pokhvishcheva ◽  
Maria A. Peshkova
Keyword(s):  
Sensor Arrays ◽  
Color Analysis ◽  
Optochemical Sensor

scholarly journals Silicon-based Biosensors for Rapid Detection of Protein or Nucleic Acid Targets

2001 ◽  
Vol 47 (10) ◽  
pp. 1894-1900 ◽  
Author(s):  
Robert Jenison ◽  
Helen La ◽  
Ayla Haeberli ◽  
Rachel Ostroff ◽  
Barry Polisky
Keyword(s):  
Thin Film ◽  
Nucleic Acid ◽  
Interferon Γ ◽  
Wild Type ◽  
Signal To Noise ◽  
Cytokine Detection ◽  
Apparent Color ◽  
Multianalyte Detection ◽  
A Charge ◽  
Silicon Based

Abstract Background: We developed a silicon-based biosensor that generates visual, qualitative results or quantitative results for the detection of protein or nucleic acid targets in a multiplex format. Methods: Capture probes were immobilized either passively or covalently on the optically coated surface of the biosensor. Intermolecular interactions of the immobilized capture probe with specific target molecules were transduced into a molecular thin film. Thin films were generated by enzyme-catalyzed deposition in the vicinity of the surface-bound target. The increased thickness on the surface changed the apparent color of the biosensor by altering the interference pattern of reflected light. Results: Cytokine detection was achieved in a 40-min multiplex assay. Detection limits were 4 ng/L for interleukin (IL)-6, 31 ng/L for IL1-β, and 437 ng/L for interferon-γ. In multianalyte experiments, cytokines were specifically detected with signal-to-noise ratios ranging from 15 to 80. With a modified optical surface, specificity was also demonstrated in a nucleic acid array with unambiguous discrimination of single-base changes in a 15-min assay. For homozygous wild-type and homozygous mutant samples, signal-to-noise ratios of ∼100 were observed. Heterozygous samples yielded approximately equivalent signals for wild-type and mutant capture probes. Conclusions: The thin-film biosensor allows rapid, sensitive, and specific detection of protein or nucleic acid targets in an array format with results read visually or quantified with a charge-coupled device camera. This biosensor is suited for multianalyte detection in clinical diagnostic assays.

Optical PMMA chip for multianalyte detection

2007 ◽  
Author(s):  
F. Baldini ◽  
A. Carloni ◽  
R. Falciai ◽  
A. Giannetti ◽  
A. Mencaglia ◽  
...  
Keyword(s):  
Multianalyte Detection

scholarly journals Electric field induced surface-enhanced Raman spectroscopy for multianalyte detection

2015 ◽  
Vol 17 (11) ◽  
pp. 7095-7099 ◽  
Author(s):  
Sumeet Walia ◽  
Aditya K. Shah ◽  
Paul R. Stoddart ◽  
Madhu Bhaskaran ◽  
Sharath Sriram
Keyword(s):  
Raman Spectroscopy ◽  
Electric Field ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Multianalyte Detection ◽  
Sers Sensing

This work demonstrates the ability to detect and isolate an analyte from a multianalyte mixture by SERS sensing.

Fluorescence-based optochemical sensor on flexible foils

2012 ◽  
Author(s):  
Sandeep Kalathimekkad ◽  
Jeroen Missinne ◽  
Juan Diego Arias Espinoza ◽  
Bram Van Hoe ◽  
Erwin Bosman ◽  
...  
Keyword(s):  
Flexible Foils ◽  
Optochemical Sensor
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