A difference imaging technique for monitoring real-time changes in morphology within the cell, tissue, and organism spatial domain

2010 ◽  
Author(s):  
E. S. McLamore ◽  
M. Stensberg ◽  
G. Yale ◽  
H. Ochoa-Acuna ◽  
M. Sepulveda ◽  
...  
Keyword(s):  
Real Time ◽  
Imaging Technique ◽  
Spatial Domain ◽  
Cell Tissue ◽  
Time Changes ◽  
Difference Imaging

FastCam: Real-Time Implementation of the Lucky Imaging Technique using FPGA

2008 ◽  
Author(s):  
J. Piqueras ◽  
L. Rodriguez-Ramos ◽  
Y. Martin ◽  
J. J. Martinez-Alvarez
Keyword(s):  
Real Time ◽  
Imaging Technique

ITVT-10. Using functional Ultrasound (fUS) for real-time, depth-resolved functional and vascular delineation of brain tumors with micrometer-millisecond precision

2021 ◽  
Vol 23 (Supplement_6) ◽  
pp. vi230-vi230
Author(s):  
Sadaf Soloukey ◽  
Luuk Verhoef ◽  
Frits Mastik ◽  
Bastian Generowicz ◽  
Eelke Bos ◽  
...  
Keyword(s):  
High Resolution ◽  
Real Time ◽  
Cerebral Blood Volume ◽  
Imaging Technique ◽  
Power Doppler ◽  
Ease Of Use ◽  
Frame Rate ◽  
Neurosurgical Procedures ◽  
Vascular Morphology

Abstract BACKGROUND Neurosurgical practice still relies heavily on pre-operatively acquired images to guide tumor resections, a practice which comes with inherent pitfalls such as registration inaccuracy due to brain shift, and lack of real-time functional or morphological feedback. Here we describe functional Ultrasound (fUS) as a new high-resolution, depth-resolved, MRI/CT-registered imaging technique able to detect functional regions and vascular morphology during awake and anesthesized tumor resections. MATERIALS AND METHODS fUS relies on high-frame-rate (HFR) ultrasound, making the technique sensitive to very small motions caused by vascular dynamics (µDoppler) and allowing measurements of changes in cerebral blood volume (CBV) with micrometer-millisecond precision. This opens up the possibility to 1) detect functional response, as CBV-changes reflect changes in metabolism of activated neurons through neurovascular coupling, and 2) visualize in-vivo vascular morphology of pathological and healthy tissue with high resolution at unprecedented depths. During a range of anesthetized and awake neurosurgical procedures we acquired vascular and functional images of brain and spinal cord using conventional ultrasound probes connected to a research acquisition system. Building on Brainlab’s Intra-Operative Navigation modules, we co-registered our intra-operative Power Doppler Images (PDIs) to patient-registered MRI/CT-data in real-time. RESULTS During meningioma and glioma resections, our co-registered PDIs revealed fUS’ ability to visualize the tumor’s feeding vessels and vascular borders in real-time, with a level of detail unprecedented by conventional MRI-sequences. During awake resections, fUS was able to detect distinct, ESM-confirmed functional areas as activated during conventional motor and language tasks. In all cases, images were acquired with micrometer-millisecond (300 µm, 1.5–2.0 ms) precision at imaging depths exceeding 5 cm. CONCLUSION fUS is a new real-time, high-resolution and depth-resolved imaging technique, combining favorable imaging specifications with characteristics such as mobility and ease of use which are uniquely beneficial for a potential image-guided neurosurgical tool.

scholarly journals GROWTH on S190426c: Real-time Search for a Counterpart to the Probable Neutron Star–Black Hole Merger using an Automated Difference Imaging Pipeline for DECam

2019 ◽  
Vol 881 (1) ◽  
pp. L7 ◽  
Author(s):  
Daniel A. Goldstein ◽  
Igor Andreoni ◽  
Peter E. Nugent ◽  
Mansi M. Kasliwal ◽  
Michael W. Coughlin ◽  
...  
Keyword(s):  
Black Hole ◽  
Neutron Star ◽  
Real Time ◽  
Difference Imaging

scholarly journals Real-time visualization of electromagnetic waves propagating in air using live electro-optic imaging technique

2010 ◽  
Vol 18 (10) ◽  
pp. 10029 ◽  
Author(s):  
Atsushi Kanno ◽  
Kiyotaka Sasagawa ◽  
Takahiro Shiozawa ◽  
Masahiro Tsuchiya
Keyword(s):  
Real Time ◽  
Electromagnetic Waves ◽  
Imaging Technique ◽  
Electro Optic ◽  
Real Time Visualization
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