FastCam: Real-Time Implementation of the Lucky Imaging Technique using FPGA

2008 ◽  
Author(s):  
J. Piqueras ◽  
L. Rodriguez-Ramos ◽  
Y. Martin ◽  
J. J. Martinez-Alvarez
Keyword(s):  
Real Time ◽  
Imaging Technique

ITVT-10. Using functional Ultrasound (fUS) for real-time, depth-resolved functional and vascular delineation of brain tumors with micrometer-millisecond precision

2021 ◽  
Vol 23 (Supplement_6) ◽  
pp. vi230-vi230
Author(s):  
Sadaf Soloukey ◽  
Luuk Verhoef ◽  
Frits Mastik ◽  
Bastian Generowicz ◽  
Eelke Bos ◽  
...  
Keyword(s):  
High Resolution ◽  
Real Time ◽  
Cerebral Blood Volume ◽  
Imaging Technique ◽  
Power Doppler ◽  
Ease Of Use ◽  
Frame Rate ◽  
Neurosurgical Procedures ◽  
Vascular Morphology

Abstract BACKGROUND Neurosurgical practice still relies heavily on pre-operatively acquired images to guide tumor resections, a practice which comes with inherent pitfalls such as registration inaccuracy due to brain shift, and lack of real-time functional or morphological feedback. Here we describe functional Ultrasound (fUS) as a new high-resolution, depth-resolved, MRI/CT-registered imaging technique able to detect functional regions and vascular morphology during awake and anesthesized tumor resections. MATERIALS AND METHODS fUS relies on high-frame-rate (HFR) ultrasound, making the technique sensitive to very small motions caused by vascular dynamics (µDoppler) and allowing measurements of changes in cerebral blood volume (CBV) with micrometer-millisecond precision. This opens up the possibility to 1) detect functional response, as CBV-changes reflect changes in metabolism of activated neurons through neurovascular coupling, and 2) visualize in-vivo vascular morphology of pathological and healthy tissue with high resolution at unprecedented depths. During a range of anesthetized and awake neurosurgical procedures we acquired vascular and functional images of brain and spinal cord using conventional ultrasound probes connected to a research acquisition system. Building on Brainlab’s Intra-Operative Navigation modules, we co-registered our intra-operative Power Doppler Images (PDIs) to patient-registered MRI/CT-data in real-time. RESULTS During meningioma and glioma resections, our co-registered PDIs revealed fUS’ ability to visualize the tumor’s feeding vessels and vascular borders in real-time, with a level of detail unprecedented by conventional MRI-sequences. During awake resections, fUS was able to detect distinct, ESM-confirmed functional areas as activated during conventional motor and language tasks. In all cases, images were acquired with micrometer-millisecond (300 µm, 1.5–2.0 ms) precision at imaging depths exceeding 5 cm. CONCLUSION fUS is a new real-time, high-resolution and depth-resolved imaging technique, combining favorable imaging specifications with characteristics such as mobility and ease of use which are uniquely beneficial for a potential image-guided neurosurgical tool.

scholarly journals Real-time visualization of electromagnetic waves propagating in air using live electro-optic imaging technique

2010 ◽  
Vol 18 (10) ◽  
pp. 10029 ◽  
Author(s):  
Atsushi Kanno ◽  
Kiyotaka Sasagawa ◽  
Takahiro Shiozawa ◽  
Masahiro Tsuchiya
Keyword(s):  
Real Time ◽  
Electromagnetic Waves ◽  
Imaging Technique ◽  
Electro Optic ◽  
Real Time Visualization

scholarly journals A Semi-3D Real-Time Imaging Technique for Measuring Bone Cell Deformation Under Fluid Flow

2009 ◽  
Author(s):  
Andrew D. Baik ◽  
X. Lucas Lu ◽  
Bo Huo ◽  
X. Sherry Liu ◽  
Cheng Dong ◽  
...  
Keyword(s):  
Fluid Flow ◽  
Real Time ◽  
Bone Cells ◽  
Imaging Technique ◽  
Shear Loading ◽  
Cell Deformation ◽  
Directional Information ◽  
Biochemical Pathways ◽  
Volume Dilatation ◽  
A Cell

Bone cells respond to fluid shear loading by activating various biochemical pathways, mediating a dynamic process of bone formation and resorption. The whole-cell volume dilatation [1] and regional deformation of intracellular structures [2] may be able to directly activate and modulate relevant biochemical pathways. Therefore, understanding how bone cells deform under fluid flow can help elucidate the fundamental mechanisms by which mechanical stimuli are able to initiate biochemical responses. Most studies on cell deformation have focused only on cell deformation in the plane parallel to the substrate surface. Height-dependent cell deformation has not been well characterized even though it may contribute greatly to mechanotransduction mechanisms. Traditional techniques to obtain this additional height information of a cell-body, such as confocal and deconvolution microscopy, are inherently limited by the timescale under which the deformational information can be visualized. Previous studies have investigated cell adhesion to substrate under flow using a single view side-view imaging technique [3, 4]. In this study, we present a novel technique that is able to image a single cell simultaneously in two orthogonal planes to obtain real-time images of a cell at a millisecond timescale. Thus, the objectives of this study were to: (1) develop an imaging technique to visualize the depth-directional information of a cell simultaneously with the traditional 2D view; (2) map out the strain fields of the cell by image analysis; and (3) investigate the viscoelastic behavior of osteoblasts under steady fluid flow.

scholarly journals Optimization and evaluation of multiple gating beam delivery in a synchrotron-based proton beam scanning system using a real-time imaging technique

2016 ◽  
Vol 32 (7) ◽  
pp. 932-937 ◽  
Author(s):  
Takahiro Yamada ◽  
Naoki Miyamoto ◽  
Taeko Matsuura ◽  
Seishin Takao ◽  
Yusuke Fujii ◽  
...  
Keyword(s):  
Real Time ◽  
Proton Beam ◽  
Imaging Technique ◽  
Scanning System ◽  
Beam Scanning ◽  
Real Time Imaging ◽  
Beam Delivery
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