scholarly journals Transcranial LED therapy for cognitive dysfunction in chronic, mild traumatic brain injury: two case reports

2010 ◽  
Author(s):  
Margaret A. Naeser ◽  
Anita Saltmarche ◽  
Maxine H. Krengel ◽  
Michael R. Hamblin ◽  
Jeffrey A. Knight
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Cognitive Dysfunction ◽  
Mild Traumatic Brain Injury ◽  
Case Reports ◽  
Led Therapy

Vestibular, balance, microvascular and white matter neuroimaging characteristics of blast injuries and mild traumatic brain injury: Four case reports

Brain Injury ◽  
2016 ◽  
Vol 30 (12) ◽  
pp. 1501-1514 ◽  
Author(s):  
Ramtilak Gattu ◽  
Faith W. Akin ◽  
Anthony T. Cacace ◽  
Courtney D. Hall ◽  
Owen D. Murnane ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
White Matter ◽  
Mild Traumatic Brain Injury ◽  
Case Reports ◽  
Blast Injuries

Short-term DTI predictors of cognitive dysfunction in mild traumatic brain injury

Brain Injury ◽  
2008 ◽  
Vol 22 (2) ◽  
pp. 115-122 ◽  
Author(s):  
Laura Miles ◽  
Robert I. Grossman ◽  
Glyn Johnson ◽  
James S. Babb ◽  
Leonard Diller ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Cognitive Dysfunction ◽  
Mild Traumatic Brain Injury ◽  
Short Term

scholarly journals Delayed Sequelae Related to Mild Traumatic Brain Injury in Children

2020 ◽  
Vol 7 ◽  
pp. 2333794X2094798
Author(s):  
Akella Chendrasekhar ◽  
Brandon Kuczabski ◽  
Douglas Cohen ◽  
Melissa Grageda ◽  
Daniel Genovese-Scullin ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Injury Severity Score ◽  
Mild Traumatic Brain Injury ◽  
Severity Score ◽  
Injury Severity ◽  
Case Reports ◽  
Residual Effects ◽  
Concussive Injury

Delayed sequelae from mild traumatic brain injury (Glasgow Coma Score at admission >13, TBI) has been documented in case reports however larger studies of these effects are sparse. We undertook a telephone based survey to assess the long term sequelae of TBI. We tracked 100 pediatric TBI patients via our trauma registry for demographic data including age, injury severity, and mechanism of injury. Then we proceeded to contact these patient’s parents via telephone. We asked regarding residual symptoms and signs of concussive injury. Duration out from initial concussive injury ranged from 4 to 68 months. The parents of 66 boys and 34 girls were surveyed. The age of the patients at the time of mild TBI ranged from 1 to 14 years. The injury severity score ranged from 1 to 21. One being the most common Injury severity score. Thirty-three percent of patients had residual effects of concussion at the time of telephone survey. Fourteen percent had memory loss issues, 21% had anxiety/depression issues, 20% had learning disability issues, and 15% had sleep disturbance issues. Duration of time post concussive injury, mechanism, and age did not influence incidence of sequelae. Mild traumatic brain injury has significant long term sequelae. Better identifying characteristics are needed to characterize patients susceptible to long term residual effects of concussion.

scholarly journals Improving Visual Function after Mild Traumatic Brain Injury Using a Vision Therapy Program: Case Reports

2020 ◽  
Vol 10 (12) ◽  
pp. 947
Author(s):  
Mona-Lisa Möller ◽  
Susanna Melkas ◽  
Jan Johansson
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Mild Traumatic Brain Injury ◽  
Case Reports ◽  
Face To Face ◽  
Rehabilitation Professionals ◽  
Therapy Program ◽  
Convergence Insufficiency ◽  
Home Based ◽  
Vision Therapy

This case report describes the outcome of vision therapy for three patients who were referred to therapy due to visual symptoms after mild traumatic brain injury (MTBI). The criterion for inclusion was a high score (>21p) on the Convergence Insufficiency Symptom Survey (CISS) scale. The vision therapy program (VTP) included both face-to-face sessions and home-based tasks. Cases #1 and #2 had a substantial CISS scale evaluation improvement, and case #2 normalized the CISS scale score from 36 to 19. All patients agreed that vision therapy helped them understand their own vision and changes in their vision, which helped their overall recovery after MTBI. Rehabilitation professionals have an important role in screening for vision impairments and treating functional vision challenges after mild traumatic brain injury.

scholarly journals Improvements in Gulf War Illness Symptoms After Near-Infrared Transcranial and Intranasal Photobiomodulation: Two Case Reports

2019 ◽  
Vol 184 (9-10) ◽  
pp. e568-e574 ◽  
Author(s):  
Linda L Chao
Keyword(s):  
Traumatic Brain Injury ◽  
At Risk ◽  
Brain Injury ◽  
Cognitive Dysfunction ◽  
Musculoskeletal Pain ◽  
Near Infrared ◽  
Case Reports ◽  
Gulf War ◽  
Gulf War Illness ◽  
Us Veterans

Abstract At least one-fourth of US veterans who served in the 1990–1991 Gulf War (GW) are affected by the chronic symptomatic illness known as Gulf War illness (GWI). This condition typically includes some combination of fatigue, headaches, cognitive dysfunction, musculoskeletal pain, and respiratory, gastrointestinal and dermatologic complaints. To date, effective treatments for GWI have been elusive. Photobiomodulation (PBM) describes the non-pharmacological, non-thermal use of light to stimulate, heal, and protect tissue that has either been injured, is degenerating, or else is at risk of dying. Significant benefits have been reported following application of transcranial PBM to humans with acute stoke, traumatic brain injury (TBI), and dementia. This report describes the first documentation of improved GWI symptoms in two GW veterans following 12 weeks of PBM treatments.

scholarly journals Iron Metabolism Disorders for Cognitive Dysfunction After Mild Traumatic Brain Injury

2021 ◽  
Vol 15 ◽  
Author(s):  
Suna Huang ◽  
Su Li ◽  
Hua Feng ◽  
Yujie Chen
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Cognitive Dysfunction ◽  
Mild Traumatic Brain Injury ◽  
Neurological Diseases ◽  
Nerve Fibers ◽  
Iron Deposition ◽  
Neural Cells ◽  
Initial Symptoms

Traumatic brain injury (TBI) is one of the most harmful forms of acute brain injury and predicted to be one of the three major neurological diseases that cause neurological disabilities by 2030. A series of secondary injury cascades often cause cognitive dysfunction of TBI patients leading to poor prognosis. However, there are still no effective intervention measures, which drive us to explore new therapeutic targets. In this process, the most part of mild traumatic brain injury (mTBI) is ignored because its initial symptoms seemed not serious. Unfortunately, the ignored mTBI accounts for 80% of the total TBI, and a large part of the patients have long-term cognitive dysfunction. Iron deposition has been observed in mTBI patients and accompanies the whole pathological process. Iron accumulation may affect long-term cognitive dysfunction from three pathways: local injury, iron deposition induces tau phosphorylation, the formation of neurofibrillary tangles; neural cells death; and neural network damage, iron deposition leads to axonal injury by utilizing the iron sensibility of oligodendrocytes. Thus, iron overload and metabolism dysfunction was thought to play a pivotal role in mTBI pathophysiology. Cerebrospinal fluid-contacting neurons (CSF-cNs) located in the ependyma have bidirectional communication function between cerebral–spinal fluid and brain parenchyma, and may participate in the pathway of iron-induced cognitive dysfunction through projected nerve fibers and transmitted factor, such as 5-hydroxytryptamine, etc. The present review provides an overview of the metabolism and function of iron in mTBI, and to seek a potential new treatment target for mTBI with a novel perspective through combined iron and CSF-cNs.

scholarly journals White matter correlates of cognitive dysfunction after mild traumatic brain injury

Neurology ◽  
2014 ◽  
Vol 83 (6) ◽  
pp. 494-501 ◽  
Author(s):  
I. D. Croall ◽  
C. J. A. Cowie ◽  
J. He ◽  
A. Peel ◽  
J. Wood ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
White Matter ◽  
Cognitive Dysfunction ◽  
Mild Traumatic Brain Injury
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