scholarly journals Spatial resolution of ultrasound-modulated optical tomography used for the detection of absorbing and scattering objects in thick scattering media

2010 ◽  
Author(s):  
Guy Rousseau ◽  
Alain Blouin ◽  
Jean-Pierre Monchalin
Keyword(s):  
Spatial Resolution ◽  
Optical Tomography ◽  
Scattering Media

scholarly journals Optimal Analysis Method for Dynamic Contrast-Enhanced Diffuse Optical Tomography

2011 ◽  
Vol 2011 ◽  
pp. 1-13 ◽  
Author(s):  
Michael Ghijsen ◽  
Yuting Lin ◽  
Mitchell Hsing ◽  
Orhan Nalcioglu ◽  
Gultekin Gulsen
Keyword(s):  
Spatial Resolution ◽  
Animal Studies ◽  
Imaging Modality ◽  
A Priori ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Dynamic Contrast Enhanced ◽  
Promising Tool ◽  
Reconstruction Methods ◽  
Contrast Enhanced

Diffuse Optical Tomography (DOT) is an optical imaging modality that has various clinical applications. However, the spatial resolution and quantitative accuracy of DOT is poor due to strong photon scatting in biological tissue. Structurala prioriinformation from another high spatial resolution imaging modality such as Magnetic Resonance Imaging (MRI) has been demonstrated to significantly improve DOT accuracy. In addition, a contrast agent can be used to obtain differential absorption images of the lesion by using dynamic contrast enhanced DOT (DCE-DOT). This produces a relative absorption map that consists of subtracting a reconstructed baseline image from reconstructed images in which optical contrast is included. In this study, we investigated and compared different reconstruction methods and analysis approaches for regular endogenous DOT and DCE-DOT with and without MR anatomicala prioriinformation for arbitrarily-shaped objects. Our phantom and animal studies have shown that superior image quality and higher accuracy can be achieved using DCE-DOT together with MR structurala prioriinformation. Hence, implementation of a combined MRI-DOT system to image ICG enhancement can potentially be a promising tool for breast cancer imaging.

Spatial resolution and scanning time in the optical tomography of absorbing 'phantoms' under multiple scattering conditions

2000 ◽  
Vol 30 (1) ◽  
pp. 78-80 ◽  
Author(s):  
E V Malikov ◽  
V M Petnikova ◽  
D A Chursin ◽  
Vladimir V Shuvalov ◽  
I V Shutov
Keyword(s):  
Multiple Scattering ◽  
Spatial Resolution ◽  
Optical Tomography ◽  
Scanning Time

Optical Tomography With a Least Square Finite Element Formulation of the Collimated Irradiation in Frequency Domain

2010 ◽  
Author(s):  
Olivier Balima ◽  
Joan Boulanger ◽  
Andre´ Charette ◽  
Daniel Marceau
Keyword(s):  
Finite Element ◽  
Optical Properties ◽  
Frequency Domain ◽  
Complex Geometry ◽  
Numerical Study ◽  
Optical Tomography ◽  
Least Square ◽  
Finite Element Formulation ◽  
Element Formulation ◽  
Scattering Media

This paper presents a numerical study of optical tomography in frequency domain for the reconstruction of optical properties of scattering and absorbing media with collimated irradiation light sources. The forward model is a least square finite element formulation of the collimated irradiation problem where the intensity is separated into its collimated and scattered parts. This model does not use any empirical stabilization and moreover the collimated source direction is taken into account. The inversion uses a gradient type minimization method where the gradient is computed through an adjoint formulation. Scaling is used to avoid numerical round errors, as the output readings at detectors are very low. Numerical reconstructions of optical properties of absorbing and scattering media with simulated data (noised and noise-free) are achieved in a complex geometry with satisfactory results. The results show that complex geometries are well handled with the proposed method.

scholarly journals Hierarchical Bayesian estimation improves depth accuracy and spatial resolution of diffuse optical tomography

2012 ◽  
Vol 20 (18) ◽  
pp. 20427 ◽  
Author(s):  
Takeaki Shimokawa ◽  
Takashi Kosaka ◽  
Okito Yamashita ◽  
Nobuo Hiroe ◽  
Takashi Amita ◽  
...  
Keyword(s):  
Bayesian Estimation ◽  
Spatial Resolution ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Hierarchical Bayesian ◽  
Hierarchical Bayesian Estimation

Use of backprojection algorithms of filtered shadows for optical tomography of strongly scattering media

2001 ◽  
Author(s):  
Alexander G. Kalintsev ◽  
Alexander B. Konovalov ◽  
Olga V. Kravtsenyuk ◽  
Igor I. Kutuzov ◽  
Oleg V. Lyamtsev ◽  
...  
Keyword(s):  
Optical Tomography ◽  
Scattering Media

Improving spatial resolution and contrast in ultrasound modulated optical tomography

2012 ◽  
Author(s):  
N. T. Huynh ◽  
H. Ruan ◽  
M. L. Mather ◽  
B. R. Hayes-Gill ◽  
S. P. Morgan
Keyword(s):  
Spatial Resolution ◽  
Optical Tomography
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