Spatial resolution and scanning time in the optical tomography of absorbing 'phantoms' under multiple scattering conditions

2000 ◽  
Vol 30 (1) ◽  
pp. 78-80 ◽  
Author(s):  
E V Malikov ◽  
V M Petnikova ◽  
D A Chursin ◽  
Vladimir V Shuvalov ◽  
I V Shutov
Keyword(s):  
Multiple Scattering ◽  
Spatial Resolution ◽  
Optical Tomography ◽  
Scanning Time

scholarly journals Optimal Analysis Method for Dynamic Contrast-Enhanced Diffuse Optical Tomography

2011 ◽  
Vol 2011 ◽  
pp. 1-13 ◽  
Author(s):  
Michael Ghijsen ◽  
Yuting Lin ◽  
Mitchell Hsing ◽  
Orhan Nalcioglu ◽  
Gultekin Gulsen
Keyword(s):  
Spatial Resolution ◽  
Animal Studies ◽  
Imaging Modality ◽  
A Priori ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Dynamic Contrast Enhanced ◽  
Promising Tool ◽  
Reconstruction Methods ◽  
Contrast Enhanced

Diffuse Optical Tomography (DOT) is an optical imaging modality that has various clinical applications. However, the spatial resolution and quantitative accuracy of DOT is poor due to strong photon scatting in biological tissue. Structurala prioriinformation from another high spatial resolution imaging modality such as Magnetic Resonance Imaging (MRI) has been demonstrated to significantly improve DOT accuracy. In addition, a contrast agent can be used to obtain differential absorption images of the lesion by using dynamic contrast enhanced DOT (DCE-DOT). This produces a relative absorption map that consists of subtracting a reconstructed baseline image from reconstructed images in which optical contrast is included. In this study, we investigated and compared different reconstruction methods and analysis approaches for regular endogenous DOT and DCE-DOT with and without MR anatomicala prioriinformation for arbitrarily-shaped objects. Our phantom and animal studies have shown that superior image quality and higher accuracy can be achieved using DCE-DOT together with MR structurala prioriinformation. Hence, implementation of a combined MRI-DOT system to image ICG enhancement can potentially be a promising tool for breast cancer imaging.

scholarly journals Hierarchical Bayesian estimation improves depth accuracy and spatial resolution of diffuse optical tomography

2012 ◽  
Vol 20 (18) ◽  
pp. 20427 ◽  
Author(s):  
Takeaki Shimokawa ◽  
Takashi Kosaka ◽  
Okito Yamashita ◽  
Nobuo Hiroe ◽  
Takashi Amita ◽  
...  
Keyword(s):  
Bayesian Estimation ◽  
Spatial Resolution ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Hierarchical Bayesian ◽  
Hierarchical Bayesian Estimation

Improving spatial resolution and contrast in ultrasound modulated optical tomography

2012 ◽  
Author(s):  
N. T. Huynh ◽  
H. Ruan ◽  
M. L. Mather ◽  
B. R. Hayes-Gill ◽  
S. P. Morgan
Keyword(s):  
Spatial Resolution ◽  
Optical Tomography

scholarly journals Spatial resolution in depth for time-resolved diffuse optical tomography using short source-detector separations

2014 ◽  
Vol 6 (1) ◽  
pp. 1 ◽  
Author(s):  
Agathe Puszka ◽  
Laura Di Sieno ◽  
Alberto Dalla Mora ◽  
Antonio Pifferi ◽  
Davide Contini ◽  
...  
Keyword(s):  
Spatial Resolution ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Time Resolved

scholarly journals Towards atomic resolution in sodium titanate nanotubes using near-edge X-ray-absorption fine-structure spectromicroscopy combined with multichannel multiple-scattering calculations

2012 ◽  
Vol 3 ◽  
pp. 789-797 ◽  
Author(s):  
Carla Bittencourt ◽  
Peter Krüger ◽  
Maureen J Lagos ◽  
Xiaoxing Ke ◽  
Gustaaf Van Tendeloo ◽  
...  
Keyword(s):  
Fine Structure ◽  
Multiple Scattering ◽  
Spatial Resolution ◽  
Sodium Titanate ◽  
Titanate Nanotubes ◽  
Theoretical Modelling ◽  
Hydroxyl Groups ◽  
X Ray ◽  
Absorption Fine ◽  
X Ray Absorption

Recent advances in near-edge X-ray-absorption fine-structure spectroscopy coupled with transmission X-ray microscopy (NEXAFS–TXM) allow large-area mapping investigations of individual nano-objects with spectral resolution up to E/ΔE = 104 and spatial resolution approaching 10 nm. While the state-of-the-art spatial resolution of X-ray microscopy is limited by nanostructuring process constrains of the objective zone plate, we show here that it is possible to overcome this through close coupling with high-level theoretical modelling. Taking the example of isolated bundles of hydrothermally prepared sodium titanate nanotubes ((Na,H)TiNTs) we are able to unravel the complex nanoscale structure from the NEXAFS–TXM data using multichannel multiple-scattering calculations, to the extent of being able to associate specific spectral features in the O K-edge and Ti L-edge with oxygen atoms in distinct sites within the lattice. These can even be distinguished from the contribution of different hydroxyl groups to the electronic structure of the (Na,H)TiNTs.

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