Synthesis and characterization of nano spherical hydroxyapatite for drug delivery and tissue engineering

Author(s):  
P. Michael S. L. Shanthi ◽  
M. Ashok ◽  
T. Balasubramanian ◽  
A. P. Uthirakumar
2016 ◽  
Vol 7 (17) ◽  
pp. 2976-2985 ◽  
Author(s):  
Ji-Yu Lin ◽  
Po-Liang Lai ◽  
Yuan-Kai Lin ◽  
Sydney Peng ◽  
Li-Yu Lee ◽  
...  

Herein, we report the synthesis and characterization of a novel positively charged thermosensitive hydrogel prepared from poloxamer (PLX)-poly(l-alanine-lysine) (Lys-Ala-PLX-Ala-Lys) that demonstrates potential in biomedical applications including tissue engineering and drug delivery.


2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Lei Xiang ◽  
Wenguo Cui

Abstract During the past decades, photo-crosslinked gelatin hydrogel (methacrylated gelatin, GelMA) has gained a lot of attention due to its remarkable application in the biomedical field. It has been widely used in cell transplantation, cell culture and drug delivery, based on its crosslinking to form hydrogels with tunable mechanical properties and excellent bio-compatibility when exposed to light irradiation to mimic the micro-environment of native extracellular matrix (ECM). Because of its unique biofunctionality and mechanical tenability, it has also been widely applied in the repair and regeneration of bone, heart, cornea, epidermal tissue, cartilage, vascular, peripheral nerve, oral mucosa, and skeletal muscle et al. The purpose of this review is to summarize the recent application of GelMA in drug delivery and tissue engineering field. Moreover, this review article will briefly introduce both the development of GelMA and the characterization of GelMA. Finally, we discuss the challenges and future development prospects of GelMA as a tissue engineering material and drug or gene delivery carrier, hoping to contribute to accelerating the development of GelMA in the biomedical field. Graphical abstract


2021 ◽  
Vol 32 (5) ◽  
pp. 1924-1950
Author(s):  
Amir Ghaderpour ◽  
Zohreh Hoseinkhani ◽  
Reza Yarani ◽  
Sina Mohammadiani ◽  
Farshid Amiri ◽  
...  

RSC Advances ◽  
2021 ◽  
Vol 11 (16) ◽  
pp. 9076-9085
Author(s):  
Kanchan Yadav ◽  
Megha Das ◽  
Nurul Hassan ◽  
Archana Mishra ◽  
Jayeeta Lahiri ◽  
...  

A novel nanodot-using protein has been synthesized for the live cell imaging and drug delivery of melatonin in breast cancer cells. Its unique properties hold potential for various biomedical applications in the field of bioimaging and drug delivery.


2020 ◽  
Vol 21 (8) ◽  
pp. 3332-3341 ◽  
Author(s):  
Richard M. England ◽  
Jennifer I. Moss ◽  
Anders Gunnarsson ◽  
Jeremy S. Parker ◽  
Marianne B. Ashford

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