A poloxamer-polypeptide thermosensitive hydrogel as a cell scaffold and sustained release depot

2016 ◽  
Vol 7 (17) ◽  
pp. 2976-2985 ◽  
Author(s):  
Ji-Yu Lin ◽  
Po-Liang Lai ◽  
Yuan-Kai Lin ◽  
Sydney Peng ◽  
Li-Yu Lee ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Sustained Release ◽  
Biomedical Applications ◽  
Synthesis And Characterization ◽  
Thermosensitive Hydrogel ◽  
Cell Scaffold ◽  
A Cell ◽  
Positively Charged

Herein, we report the synthesis and characterization of a novel positively charged thermosensitive hydrogel prepared from poloxamer (PLX)-poly(l-alanine-lysine) (Lys-Ala-PLX-Ala-Lys) that demonstrates potential in biomedical applications including tissue engineering and drug delivery.

scholarly journals Synthesis and characterization of novel protein nanodots as drug delivery carriers with an enhanced biological efficacy of melatonin in breast cancer cells

RSC Advances ◽  
2021 ◽  
Vol 11 (16) ◽  
pp. 9076-9085
Author(s):  
Kanchan Yadav ◽  
Megha Das ◽  
Nurul Hassan ◽  
Archana Mishra ◽  
Jayeeta Lahiri ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Cancer Cells ◽  
Live Cell Imaging ◽  
Biomedical Applications ◽  
Breast Cancer Cells ◽  
Cell Imaging ◽  
Synthesis And Characterization ◽  
Novel Protein

A novel nanodot-using protein has been synthesized for the live cell imaging and drug delivery of melatonin in breast cancer cells. Its unique properties hold potential for various biomedical applications in the field of bioimaging and drug delivery.

Synthesis and characterization of nano spherical hydroxyapatite for drug delivery and tissue engineering

2009 ◽  
Author(s):  
P. Michael S. L. Shanthi ◽  
M. Ashok ◽  
T. Balasubramanian ◽  
A. P. Uthirakumar
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Synthesis And Characterization

Biodegradable polycaprolactone (PCL) based polymer and composites

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Emily Archer ◽  
Marissa Torretti ◽  
Samy Madbouly
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Ring Opening ◽  
Biomedical Applications ◽  
Drug Delivery Systems ◽  
Food Packaging ◽  
Delivery Systems ◽  
Implantable Devices

Abstract Polycaprolactone (PCL) is a biodegradable polyester that has advantages over other biopolymers, making it an extensively researched polymer. PCL is a hydrophobic, slow-degrading, synthetic polymer making it particularly interesting for the preparation of long-term implantable devices and a variety of drug delivery systems. Recently, PCL has been used for additional applications including food packaging and tissue engineering. In this chapter, the processing methods and characterization of PCL will be discussed. The chapter will summarize the synthesis of poly(α-hydroxy acid) and the ring-opening polymerization of PCL. Discussion on the biodegradability of PCL will be reviewed. The biomedical applications of PCL, such as, drug-delivery systems, medical devices, and tissue engineering will be also summarized. Finally, the chapter will conclude with a characterization section outlining recent studies focusing on PCL based composites and films.

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