Tracking contrast agents using real-time 2D photoacoustic imaging system for cardiac applications

2009 ◽  
Author(s):  
Ragnar Olafsson ◽  
Leonardo Montilla ◽  
Pier Ingram ◽  
Russell S. Witte
Keyword(s):  
Contrast Agents ◽  
Real Time ◽  
Imaging System ◽  
Photoacoustic Imaging

A pilot study of photoacoustic imaging system for improved real-time visualization of neurovascular bundle during radical prostatectomy

The Prostate ◽  
2015 ◽  
Vol 76 (3) ◽  
pp. 307-315 ◽  
Author(s):  
Akio Horiguchi ◽  
Kazuhiro Tsujita ◽  
Kaku Irisawa ◽  
Tadashi Kasamatsu ◽  
Kazuhiro Hirota ◽  
...  
Keyword(s):  
Pilot Study ◽  
Radical Prostatectomy ◽  
Real Time ◽  
Imaging System ◽  
Photoacoustic Imaging ◽  
Neurovascular Bundle ◽  
Real Time Visualization

Modification of a commercially available photoacoustic imaging system for the use of 1064nm and 532nm wavelengths to assess photoacoustic contrast agents

2013 ◽  
Author(s):  
Andrew Heinmiller ◽  
Kimberly Homan ◽  
Stanislav Emelianov ◽  
Adam Cole ◽  
Sanjiv Gambhir ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Imaging System ◽  
Photoacoustic Imaging

scholarly journals Towards clinical photoacoustic and ultrasound imaging: Probe improvement and real-time graphical user interface

2020 ◽  
Vol 245 (4) ◽  
pp. 321-329 ◽  
Author(s):  
Jeesu Kim ◽  
Eun-Yeong Park ◽  
Byullee Park ◽  
Wonseok Choi ◽  
Ki J Lee ◽  
...  
Keyword(s):  
User Interface ◽  
Real Time ◽  
Ultrasound Imaging ◽  
Graphical User Interface ◽  
Imaging System ◽  
Photoacoustic Imaging ◽  
Clinical Applications ◽  
Imaging Systems ◽  
Imaging Probe ◽  
Conventional Ultrasound

Photoacoustic imaging is a non-invasive and non-ionizing biomedical technique that has been investigated widely for various clinical applications. By taking the advantages of conventional ultrasound imaging, hand-held operation with a linear array transducer should be favorable for successful clinical translation of photoacoustic imaging. In this paper, we present new key updates contributed to the previously developed real-time clinical photoacoustic and ultrasound imaging system for improving the clinical usability of the system. We developed a seamless image optimization platform, designed a real-time parameter control software with a user-friendly graphical user interface, performed Monte Carlo simulation of the optical fluence in the imaging plane, and optimized the geometry of the imaging probe. The updated system allows optimizing of all imaging parameters while continuously acquiring the photoacoustic and ultrasound images in real-time. The updated system has great potential to be used in a variety of clinical applications such as assessing the malignancy of thyroid cancer, breast cancer, and melanoma. Impact statement Photoacoustic imaging is a promising biomedical imaging modality that can visualize both structural and functional information of biological tissue. Because of its easiness to be integrated with conventional ultrasound imaging systems, numerous studies have been conducted to develop and apply clinical photoacoustic imaging systems. However, most of the systems were not suitable for general-purpose clinical applications due to one of the following reasons: target specific design, immobility, inaccessible operation sequence, and lack of hand-held operation. This study demonstrates a real-time clinical photoacoustic and ultrasound imaging system, which can overcome the limitations of the previous systems for successful clinical translation.

Development of Real-Time 3-D Photoacoustic Imaging System Employing Spherically Curved Array Transducer

2017 ◽  
Vol 64 (8) ◽  
pp. 1223-1233 ◽  
Author(s):  
Ryo Nagaoka ◽  
Takuya Tabata ◽  
Ryo Takagi ◽  
Shin Yoshizawa ◽  
Shin-Ichiro Umemura ◽  
...  
Keyword(s):  
Real Time ◽  
Imaging System ◽  
Photoacoustic Imaging ◽  
Array Transducer ◽  
Curved Array Transducer

scholarly journals Contrast agents for photoacoustic imaging: a review of stem cell tracking

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Soorya James ◽  
Kai Neuhaus ◽  
Mary Murphy ◽  
Martin Leahy
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Contrast Agents ◽  
Real Time ◽  
Cell Tracking ◽  
Spinal Cord Injuries ◽  
Photoacoustic Imaging ◽  
Heart Diseases ◽  
Biodistribution Studies ◽  
Migration Pathways

AbstractWith the advent of stem cell therapy for spinal cord injuries, stroke, burns, macular degeneration, heart diseases, diabetes, rheumatoid arthritis and osteoarthritis; the need to track the survival, migration pathways, spatial destination and differentiation of transplanted stem cells in a clinical setting has gained increased relevance. Indeed, getting regulatory approval to use these therapies in the clinic depends on biodistribution studies. Although optoacoustic imaging (OAI) or photoacoustic imaging can detect functional information of cell activities in real-time, the selection and application of suitable contrast agents is essential to achieve optimal sensitivity and contrast for sensing at clinically relevant depths and can even provide information about molecular activity. This review explores OAI methodologies in conjunction with the specific application of exogenous contrast agents in comparison to other imaging modalities and describes the properties of exogenous contrast agents for quantitative and qualitative monitoring of stem cells. Specific characteristics such as biocompatibility, the absorption coefficient, and surface functionalization are compared and how the labelling efficiency translates to both short and long-term visualization of mesenchymal stem cells is explored. An overview of novel properties of recently developed optoacoustic contrast agents and their capability to detect disease and recovery progression in clinical settings is provided which includes newly developed exogenous contrast agents to monitor stem cells in real-time for multimodal sensing.

Real-Time Photoacoustic Imaging System Based on Phase Contrast Demodulation

2016 ◽  
Vol 53 (7) ◽  
pp. 071701
Author(s):  
张宇 Zhang Yu ◽  
薛月菊 Xue Yueju ◽  
贾金亮 Jia Jinliang ◽  
金晓勇 Jin Xiaoyong ◽  
刘洪山 Liu Hongshan ◽  
...  
Keyword(s):  
Real Time ◽  
Phase Contrast ◽  
Imaging System ◽  
Photoacoustic Imaging

scholarly journals Real-time photoacoustic imaging system for burn diagnosis

2014 ◽  
Vol 19 (8) ◽  
pp. 086013 ◽  
Author(s):  
Taiichiro Ida ◽  
Yasushi Kawaguchi ◽  
Satoko Kawauchi ◽  
Keiichi Iwaya ◽  
Hitoshi Tsuda ◽  
...  
Keyword(s):  
Real Time ◽  
Imaging System ◽  
Photoacoustic Imaging
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