Enhancing time-domain optical mammography by relocating optodes

2009 ◽  
Author(s):  
Yiwen Ma ◽  
Jingyi Wang ◽  
Feng Gao ◽  
Fang Yang ◽  
Huijuan Zhao ◽  
...  
Keyword(s):  
Time Domain ◽  
Optical Mammography

Time-domain scanning optical mammography: I. Recording and assessment of mammograms of 154 patients

2005 ◽  
Vol 50 (11) ◽  
pp. 2429-2449 ◽  
Author(s):  
Dirk Grosenick ◽  
K Thomas Moesta ◽  
Michael Möller ◽  
Jörg Mucke ◽  
Heidrun Wabnitz ◽  
...  
Keyword(s):  
Time Domain ◽  
Optical Mammography

Optical mammography in the time domain up to 1060 nm: from tests on healthy women to initial data for monitoring neoadjuvant chemotherapy

2021 ◽  
Author(s):  
Giulia Maffeis ◽  
Edoardo Ferocino ◽  
Alberto Dalla Mora ◽  
Rinaldo Cubeddu ◽  
Antonio Pifferi ◽  
...  
Keyword(s):  
Neoadjuvant Chemotherapy ◽  
Initial Data ◽  
Time Domain ◽  
Optical Mammography ◽  
Healthy Women ◽  
The Time Domain

Time-domain optical mammography: results on phantoms, healthy volunteers, and patients

1998 ◽  
Author(s):  
H. Rinneberg ◽  
D. Grosenick ◽  
H. Wabnitz ◽  
H. Danlewski ◽  
K. Moesta ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Time Domain ◽  
Optical Mammography

An efficient Jacobian scaling method for time-domain optical mammography

2010 ◽  
Vol 8 (2) ◽  
pp. 206-209
Author(s):  
马艺闻 Yiwen Ma ◽  
高峰 Feng Gao ◽  
阮平巧 Pingqiao Ruan ◽  
杨芳 Fang Yang ◽  
赵会娟 Huijuan Zhao
Keyword(s):  
Time Domain ◽  
Scaling Method ◽  
Optical Mammography

Time-Domain Optical Mammography SoftScan: Initial Results

2005 ◽  
Vol 12 (10) ◽  
pp. 1355
Author(s):  
Xavier Intes ◽  
Salim Djeziri ◽  
Zahia Ichalalene ◽  
Niculae Mincu ◽  
Yong Wang ◽  
...  
Keyword(s):  
Time Domain ◽  
Optical Mammography ◽  
Initial Results

Time-Domain Optical Mammography SoftScan

2005 ◽  
Vol 12 (8) ◽  
pp. 934-947 ◽  
Author(s):  
Xavier Intes
Keyword(s):  
Time Domain ◽  
Optical Mammography

Scanning Time-domain Optical Mammography: Detection and Characterization of Breast Tumors In Vivo

2005 ◽  
Vol 4 (5) ◽  
pp. 483-496 ◽  
Author(s):  
Herbert Rinneberg ◽  
Dirk Grosenick ◽  
K. Thomas Moesta ◽  
Jörg Mucke ◽  
Bernd Gebauer ◽  
...  
Keyword(s):  
Time Domain ◽  
Near Infrared ◽  
Strong Light ◽  
New Techniques ◽  
Optical Mammography ◽  
Scanning Time ◽  
Nir Light ◽  
Tissue Scattering

Optical mammography is one of several new techniques for breast cancer detection and characterization presently under development for clinical use that provide information other than morphologic, in particular on the biochemical and metabolic state of normal and diseased tissue. In breast tissue, scattering of red to near infrared (NIR) light dominates absorption and NIR light may penetrate several centimeters through the breast. Optical mammography avoids the use of ionizing radiation and offers the power of diffuse optical spectroscopy. However, because of strong light scattering, spatial resolution of optical mammography is generally low. The paper reviews the results of a clinical study on scanning time-domain optical mammography comprising 154 patients carrying a total of 102 carcinomas validated by histology. Ninety two of these tumors were detected in optical mammograms retrospectively and for 87 of the detected tumors optical properties and tissue parameters were derived. In addition developments on instrumentation and data analysis are covered and possible improvements of optical mammography are briefly discussed.

Detection and characterization of breast tumours by time-domain scanning optical mammography

2008 ◽  
Vol 16 (2) ◽  
Author(s):  
H. Rinneberg ◽  
D. Grosenick ◽  
K. Moesta ◽  
H. Wabnitz ◽  
J. Mucke ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Time Domain ◽  
Breast Tissue ◽  
Photon Density ◽  
Optical Mammography ◽  
Scanning Time ◽  
Model Following ◽  
Number Of Patients ◽  
Photon Density Waves ◽  
Qualitative Measure

AbstractThe paper gives a short overview of various methods of optical mammography, emphasizing scanning time-domain mammography. The results of a clinical study on time-domain optical mammography are reviewed, comprising 154 patients carrying a total of 102 carcinomas validated by histology. A visibility score attributed to each carcinoma as qualitative measure of tumour detectability indicates acceptable sensitivity but poor specificity for discrimination between malignant and benign lesions. Likewise, a multi-variate statistical analysis yields sensitivity and specificity between 80% and 85% for tumour detection and discrimination with respect to normal (healthy) breast tissue, but values less than 70% for discrimination between malignant and benign breast lesions, being too low to be of clinical relevance. For 87 of the 88 tumours detected retrospectively in both projection optical mammograms, optical properties and tissue parameters were derived based on the diffraction of photon density waves by a spherical inhomogeneity as forward model. Following injection of a bolus of indocyanine green as non-targeted absorbing contrast agent, dynamic contrast-enhanced time-domain optical mammography was carried out on a small number of patients, but no differences in wash-out kinetics of indocyanine green between tumours and healthy breast tissue were observed.

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