In vivo determination of optical properties and fluorophore characteristics of non-melanoma skin cancer

2009 ◽  
Author(s):  
Narasimhan Rajaram ◽  
Dianne Kovacic ◽  
Michael F. Migden ◽  
Jason S. Reichenberg ◽  
Tri H. Nguyen ◽  
...  
Keyword(s):  
Optical Properties ◽  
Skin Cancer ◽  
Non Melanoma Skin Cancer ◽  
Melanoma Skin

scholarly journals Multiple Roles for VEGF in Non-Melanoma Skin Cancer: Angiogenesis and Beyond

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Kelly E. Johnson ◽  
Traci A. Wilgus
Keyword(s):  
Skin Cancer ◽  
Critical Role ◽  
Tumor Development ◽  
Skin Carcinogenesis ◽  
Skin Tumors ◽  
Angiogenic Factor ◽  
Non Melanoma Skin Cancer ◽  
New Treatments ◽  
Melanoma Skin

Vascular endothelial growth factor (VEGF) is known to play a critical role in the development of non-melanoma skin cancers. VEGF is a potent pro-angiogenic factor and it is elevated in mouse and human skin tumors. The use of transgenic and knockout mice has shown that VEGF is essential for tumor development in multiple models of skin carcinogenesis and, until recently, the mechanism of action has been primarily attributed to the induction of angiogenesis. However, additional roles for VEGF have now been discovered. Keratinocytes can respond directly to VEGF, which could influence skin carcinogenesis by altering proliferation, survival, and stemness.In vivostudies have shown that loss of epidermal VEGFR-1 or neuropillin-1 inhibits carcinogenesis, indicating that VEGF can directly affect tumor cells. Additionally, VEGF has been shown to promote tumor growth by recruiting macrophages to skin tumors, which likely occurs through VEGFR-1. Overall, these new studies show that VEGF carries out functions beyond its well-established effects on angiogenesis and highlight the need to consider these alternative activities when developing new treatments for non-melanoma skin cancer.

scholarly journals Detection of Non-Melanoma Skin Cancer by in vivo Fluorescence Imaging with Fluorocoxib A

Neoplasia ◽  
2015 ◽  
Vol 17 (2) ◽  
pp. 201-207 ◽  
Author(s):  
Hyejun Ra ◽  
Emilio González-González ◽  
Md. Jashim Uddin ◽  
Bonnie L. King ◽  
Alex Lee ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Fluorescence Imaging ◽  
In Vivo Fluorescence ◽  
Non Melanoma Skin Cancer ◽  
In Vivo Fluorescence Imaging ◽  
Melanoma Skin

Does surface preparation alter ALA uptake in superficial non-melanoma skin cancer in vivo?

2008 ◽  
Vol 24 (2) ◽  
pp. 72-75 ◽  
Author(s):  
Harry Moseley ◽  
Lorenzo Brancaleon ◽  
Andrea E. Lesar ◽  
James Ferguson ◽  
Sally H. Ibbotson
Keyword(s):  
Skin Cancer ◽  
Surface Preparation ◽  
Non Melanoma Skin Cancer ◽  
Melanoma Skin

Discrimination of non-melanoma skin cancer and keratosis from normal skin tissue in vivo and ex vivo by Raman spectroscopy

2019 ◽  
Vol 100 ◽  
pp. 131-141 ◽  
Author(s):  
Ana Mara Ferreira Lima ◽  
Camila Ribeiro Daniel ◽  
Ricardo Scarparo Navarro ◽  
Benito Bodanese ◽  
Carlos Augusto Pasqualucci ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Skin Cancer ◽  
Ex Vivo ◽  
Normal Skin ◽  
Skin Tissue ◽  
Non Melanoma Skin Cancer ◽  
Melanoma Skin
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