In vivo measurements of blood vessels’ distribution in non-melanoma skin cancer by dynamic optical coherence tomography - a new quantitative measure?

2017 ◽  
Vol 24 (1) ◽  
pp. 123-128 ◽  
Author(s):  
V. Sigsgaard ◽  
L. Themstrup ◽  
P. Theut Riis ◽  
J. Olsen ◽  
G. B. Jemec
Keyword(s):  
Optical Coherence Tomography ◽  
Skin Cancer ◽  
Blood Vessels ◽  
Quantitative Measure ◽  
Optical Coherence ◽  
In Vivo Measurements ◽  
Non Melanoma Skin Cancer ◽  
Melanoma Skin

Optical coherence tomography for presurgical margin assessment of non-melanoma skin cancer - a practical approach

2013 ◽  
Vol 22 (8) ◽  
pp. 547-551 ◽  
Author(s):  
Seyed Arash Alawi ◽  
Monika Kuck ◽  
Caroline Wahrlich ◽  
Sebastian Batz ◽  
Gordon McKenzie ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Skin Cancer ◽  
Practical Approach ◽  
Optical Coherence ◽  
Margin Assessment ◽  
Non Melanoma Skin Cancer ◽  
Melanoma Skin

Histological correlates of optical coherence tomography in non-melanoma skin cancer

2012 ◽  
Vol 19 (1) ◽  
pp. e10-e19 ◽  
Author(s):  
Andrew John Coleman ◽  
Thomas James Richardson ◽  
Guy Orchard ◽  
Ayesha Uddin ◽  
Min Joo Choi ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Skin Cancer ◽  
Optical Coherence ◽  
Non Melanoma Skin Cancer ◽  
Melanoma Skin

Assessment of Optical Coherence Tomography Imaging in the Diagnosis of Non-Melanoma Skin Cancer and Benign Lesions Versus Normal Skin

2009 ◽  
Vol 35 (6) ◽  
pp. 965-972 ◽  
Author(s):  
METTE MOGENSEN ◽  
THOMAS MARTINI JOERGENSEN ◽  
BIRGIT MEINCKE NÜRNBERG ◽  
HANAN AHMAD MORSY ◽  
JAKOB B. THOMSEN ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Skin Cancer ◽  
Normal Skin ◽  
Optical Coherence ◽  
Benign Lesions ◽  
Tomography Imaging ◽  
Non Melanoma Skin Cancer ◽  
Optical Coherence Tomography Imaging ◽  
Melanoma Skin

scholarly journals Multiple Roles for VEGF in Non-Melanoma Skin Cancer: Angiogenesis and Beyond

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Kelly E. Johnson ◽  
Traci A. Wilgus
Keyword(s):  
Skin Cancer ◽  
Critical Role ◽  
Tumor Development ◽  
Skin Carcinogenesis ◽  
Skin Tumors ◽  
Angiogenic Factor ◽  
Non Melanoma Skin Cancer ◽  
New Treatments ◽  
Melanoma Skin

Vascular endothelial growth factor (VEGF) is known to play a critical role in the development of non-melanoma skin cancers. VEGF is a potent pro-angiogenic factor and it is elevated in mouse and human skin tumors. The use of transgenic and knockout mice has shown that VEGF is essential for tumor development in multiple models of skin carcinogenesis and, until recently, the mechanism of action has been primarily attributed to the induction of angiogenesis. However, additional roles for VEGF have now been discovered. Keratinocytes can respond directly to VEGF, which could influence skin carcinogenesis by altering proliferation, survival, and stemness.In vivostudies have shown that loss of epidermal VEGFR-1 or neuropillin-1 inhibits carcinogenesis, indicating that VEGF can directly affect tumor cells. Additionally, VEGF has been shown to promote tumor growth by recruiting macrophages to skin tumors, which likely occurs through VEGFR-1. Overall, these new studies show that VEGF carries out functions beyond its well-established effects on angiogenesis and highlight the need to consider these alternative activities when developing new treatments for non-melanoma skin cancer.

Sign in / Sign up

Export Citation Format

Share Document