Tolerance analysis of a micro-optical detection unit for fluorescence and absorbance measurements in lab-on-a-chip micro-channels for chromatographic applications

Author(s):  
Sara Van Overmeire ◽  
Heidi Ottevaere ◽  
Gert Desmet ◽  
Hugo Thienpont
2016 ◽  
Vol 2016 (CICMT) ◽  
pp. 000085-000088
Author(s):  
Achraf Ben Amar ◽  
Houssem Eddine Amor ◽  
Hung Cao ◽  
Ammar B. Kouki

Abstract Low temperature co-fired ceramic (LTCC) based microfluidic sensors have been developed for biomedical and environmental sensing systems. This paper introduces a microfluidic chamber based on impedance spectroscopy measurements using LTCC technology for wireless Lab-On-A-Chip (LOC) applications. To overcome the channel sagging during the fabrication process, we used sacrificial carbon tapes as solid inserts, thus guiding the LTCC to follow their shape upon lamination and then formed micro-channels. The measurement chamber was a parallel-plate capacitive structure with 85 μm gap. This platform requires a small fluid sample of less than 4 μL. The sensor formed by the microfluidic channel and capacitance structure was characterized using different dielectric materials such as air, water and acetone. We hereby present the capability of LTCC-based systems in fluid identification by detecting their electrical permittivity using capacitance measurement.


2003 ◽  
Author(s):  
James N. McMullin ◽  
H. Qiao ◽  
Sanket Goel ◽  
S. A. McColman ◽  
A. Grundmann

Author(s):  
Junqing Wu ◽  
Gaurav Soni ◽  
Dazhi Wang ◽  
Carl D. Meinhart

We have developed micropumps for microfluidics that use AC electric fields to drive aqueous fluid motion through micro channels. These pumps operate at relatively low voltages (~5–10Vrms), and high frequencies (~100kHz). They have several distinct advantages over the DC electrokinetic pumps. The low voltages make the pumps well suited for a wide variety of biosensor and “Lab-on-a-Chip” applications (e.g. PCR chip for DNA amplification). The high frequencies minimize electrolysis, so that bubbles do not form on the electrode surfaces, and do not contaminate the working fluid. The pumps can also be used as active valves or precision micro-dispensers.


Sensors ◽  
2014 ◽  
Vol 14 (8) ◽  
pp. 15458-15479 ◽  
Author(s):  
Nuno Pires ◽  
Tao Dong ◽  
Ulrik Hanke ◽  
Nils Hoivik

2012 ◽  
Vol 57 (SI-1 Track-G) ◽  
Author(s):  
F. Sauter ◽  
R. Klemm ◽  
C. Gärtner ◽  
P. Miethe ◽  
S. Henze ◽  
...  

2016 ◽  
Vol 121 ◽  
pp. 05008
Author(s):  
A.D. Avrorin ◽  
A.V. Avrorin ◽  
V.M. Aynutdinov ◽  
R. Bannash ◽  
I.A. Belolaptikov ◽  
...  

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