Image perception by expert readers as a function of patient skin entrance dose levels in digital radiography

2008 ◽  
Author(s):  
T. Lehnert ◽  
H. Korkusuz ◽  
F. Khan ◽  
T. J. Vogl ◽  
M. G. Mack
2018 ◽  
Vol 25 (2) ◽  
pp. 565-569 ◽  
Author(s):  
Christian Dullin ◽  
Jonas Albers ◽  
Giuliana Tromba ◽  
Marie Andrä ◽  
Marco Ramilli ◽  
...  

Due to the complexity of the underlying pathomechanism,in vivomouse lung-disease models continue to be of great importance in preclinical respiratory research. Longitudinal studies following the cause of a disease or evaluating treatment efficacy are of particular interest but challenging due to the small size of the mouse lung and the fast breathing rate. Synchrotron-based in-line phase-contrast computed tomography imaging has been successfully applied in lung research in various applications, but mostly at dose levels that forbid longitudinalin vivostudies. Here, the novel charge-integrating hybrid detector MÖNCH is presented, which enables imaging of mouse lungs at a pixel size of 25 µm, in less than 10 s and with an entrance dose of about 70 mGy, which therefore will allow longitudinal lung disease studies to be performed in mouse models.


2016 ◽  
Vol 21 (4) ◽  
pp. 1327-1333 ◽  
Author(s):  
Ralf Kurt Willy Schulze ◽  
Catrin Cremers ◽  
Heiko Karle ◽  
Hugo de las Heras Gala

Author(s):  
S.D. Barnard ◽  
S.D. Warner

1, 2, 9, 10-tetramethoxyaporphine phosphate (MDL-832) was once considered a potential human antitussive. MDL-832 was administered orally in the diets of Sprague-Dawley rats at dose levels of 0, 5, 10, 20, 40, 80 and 160 mg/kg/day for 3 and 6 months and in gelatin capsules to Beagle dogs at 0, 5, 10, 15, 30 and 60 mg/kg/day for 3, 6 and 12 months. Histopathologic examinations of hematoxylin and eosin-stained cerebellar sections revealed intracytoplasmic brown pigment accumulations in large fusiform neurons (presumably the motor type) of the pons. The pigment granules were found to be PAS-positive, non-acid fast, iron-free, Sudan B-positive and fuchsinophilic. Intraneuronal pigment accumulations were seen in rats after 3 months of treatment at 80 mg but not at 40 mg and after 6 months at 20 mg but not at 10 mg. For dogs the effect was observed after 3 months at 60 mg but not at 30 mg and after 12 months at 10 mg but not at 5 mg.


1974 ◽  
Author(s):  
Peter H. Henry ◽  
Thomas Q. Davis ◽  
Edward J. Engelken ◽  
Richard C. McNee ◽  
Harold N. Keiser ◽  
...  
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