Characterization of laser-induced thermal response of nanoshells for cancer treatment using magnetic-resonance temperature imaging

2007 ◽  
Author(s):  
Andrew M. Elliott ◽  
R. J. Stafford ◽  
Jon Schwartz ◽  
James Wang ◽  
Anil M. Shetty ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Cancer Treatment ◽  
Thermal Response ◽  
Temperature Imaging ◽  
Magnetic Resonance Temperature Imaging

Laser-induced thermal response and characterization of nanoparticles for cancer treatment using magnetic resonance thermal imaging

2007 ◽  
Vol 34 (7) ◽  
pp. 3102-3108 ◽  
Author(s):  
Andrew M. Elliott ◽  
R. Jason Stafford ◽  
Jon Schwartz ◽  
James Wang ◽  
Anil M. Shetty ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Cancer Treatment ◽  
Thermal Imaging ◽  
Thermal Response

Referenceless magnetic resonance temperature imaging using Gaussian process modeling

2017 ◽  
Vol 44 (7) ◽  
pp. 3545-3555 ◽  
Author(s):  
Joshua P. Yung ◽  
David Fuentes ◽  
Christopher J MacLellan ◽  
Florian Maier ◽  
Yannis Liapis ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Gaussian Process ◽  
Process Modeling ◽  
Temperature Imaging ◽  
Magnetic Resonance Temperature Imaging ◽  
Gaussian Process Modeling

scholarly journals Transcranial Magnetic Resonance Imaging– Guided Focused Ultrasound Surgery of Brain Tumors

Neurosurgery ◽  
2010 ◽  
Vol 66 (2) ◽  
pp. 323-332 ◽  
Author(s):  
Nathan McDannold ◽  
Greg T. Clement ◽  
Peter Black ◽  
Ferenc Jolesz ◽  
Kullervo Hynynen
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Focused Ultrasound ◽  
Resonance Imaging ◽  
Ultrasound Surgery ◽  
Temperature Imaging ◽  
Focused Ultrasound Surgery ◽  
Brain Surface ◽  
Magnetic Resonance Temperature Imaging ◽  
The Brain

Abstract OBJECTIVE This work evaluated the clinical feasibility of transcranial magnetic resonance imaging–guided focused ultrasound surgery. METHODS Transcranial magnetic resonance imaging–guided focused ultrasound surgery offers a potential noninvasive alternative to surgical resection. The method combines a hemispherical phased-array transducer and patient-specific treatment planning based on acoustic models with feedback control based on magnetic resonance temperature imaging to overcome the effects of the cranium and allow for controlled and precise thermal ablation in the brain. In initial trials in 3 glioblastoma patients, multiple focused ultrasound exposures were applied up to the maximum acoustic power available. Offline analysis of the magnetic resonance temperature images evaluated the temperature changes at the focus and brain surface. RESULTS We found that it was possible to focus an ultrasound beam transcranially into the brain and to visualize the heating with magnetic resonance temperature imaging. Although we were limited by the device power available at the time and thus seemed to not achieve thermal coagulation, extrapolation of the temperature measurements at the focus and on the brain surface suggests that thermal ablation will be possible with this device without overheating the brain surface, with some possible limitation on the treatment envelope. CONCLUSION Although significant hurdles remain, these findings are a major step forward in producing a completely noninvasive alternative to surgical resection for brain disorders.

TU-A-9A-04: Development of a Thermally Stable Phantom for Photoacoustic and Magnetic Resonance Temperature Imaging

2014 ◽  
Vol 41 (6Part26) ◽  
pp. 447-448
Author(s):  
K Dextraze ◽  
C MacLellan ◽  
T Mitcham ◽  
M Melancon ◽  
R Bouchard
Keyword(s):  
Magnetic Resonance ◽  
Thermally Stable ◽  
Temperature Imaging ◽  
Magnetic Resonance Temperature Imaging

scholarly journals Magnetic Resonance-Guided Laser Induced Thermal Therapy for Glioblastoma Multiforme: A Review

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Sarah E. Norred ◽  
Jacqueline Anne Johnson
Keyword(s):  
Glioblastoma Multiforme ◽  
Magnetic Resonance ◽  
Tumor Tissue ◽  
State Of The Art ◽  
Invasive Approach ◽  
Temperature Imaging ◽  
Current State ◽  
Clinical Challenge ◽  
Potential Applications ◽  
Magnetic Resonance Temperature Imaging

Magnetic resonance-guided laser induced thermotherapy (MRgLITT) has become an increasingly relevant therapy for tumor ablation due to its minimally invasive approach and broad applicability across many tissue types. The current state of the art applies laser irradiation via cooled optical fiber applicators in order to generate ablative heat and necrosis in tumor tissue. Magnetic resonance temperature imaging (MRTI) is used concurrently with this therapy to plan treatments and visualize tumor necrosis. Though application in neurosurgery remains in its infancy, MRgLITT has been found to be a promising therapy for many types of brain tumors. This review examines the current use of MRgLITT with regard to the special clinical challenge of glioblastoma multiforme and examines the potential applications of next-generation nanotherapy specific to the treatment of glioblastoma.

scholarly journals Estimating nanoparticle optical absorption with magnetic resonance temperature imaging and bioheat transfer simulation

2013 ◽  
Vol 30 (1) ◽  
pp. 47-55 ◽  
Author(s):  
Christopher J. MacLellan ◽  
David Fuentes ◽  
Andrew M. Elliott ◽  
Jon Schwartz ◽  
John D. Hazle ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Optical Absorption ◽  
Bioheat Transfer ◽  
Temperature Imaging ◽  
Magnetic Resonance Temperature Imaging
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