Stochastic reconstruction of incomplete data sets using Gibbs priors in positron emission tomography

1992 ◽  
Author(s):  
Chin-Tu Chen ◽  
Oscar H. Kapp ◽  
Wing H. Wong
Keyword(s):  
Positron Emission Tomography ◽  
Incomplete Data ◽  
Emission Tomography ◽  
Data Sets ◽  
Stochastic Reconstruction ◽  
Positron Emission

Improved Image Interpretation with Registered Thoracic CT and Positron Emission Tomography Data Sets

2002 ◽  
Vol 178 (4) ◽  
pp. 939-944 ◽  
Author(s):  
Suzanne L. Aquino ◽  
Jane C. Asmuth ◽  
Richard H. Moore ◽  
Steven B. Weise ◽  
Alan J. Fischman
Keyword(s):  
Positron Emission Tomography ◽  
Image Interpretation ◽  
Emission Tomography ◽  
Data Sets ◽  
Positron Emission Tomography Data ◽  
Thoracic Ct ◽  
Positron Emission ◽  
Tomography Data

scholarly journals Analysis of PET Neurofunctional Mapping Studies

1995 ◽  
Vol 15 (3) ◽  
pp. 492-504 ◽  
Author(s):  
John R. Votaw ◽  
Hengli H. Li
Keyword(s):  
Positron Emission Tomography ◽  
Region Of Interest ◽  
Functional Mapping ◽  
Emission Tomography ◽  
Data Sets ◽  
Statistical Uncertainty ◽  
Positron Emission

In this work, we present a method for analyzing positron emission tomography (PET) functional mapping experiments. The method is useful for identifying statistically significant differences between two PET data sets. First, uniform-variance Z-images are created and then the statistical uncertainty in region-of-interest values are calculated using a previously published method. The Z-images are calculated from the emission sinograms only

scholarly journals Validation of the Three-Dimensional Acquisition Mode in Positron Emission Tomography for the Quantitation of [18F]Fluoro-DOPA Uptake in the Human Striata

1998 ◽  
Vol 18 (9) ◽  
pp. 951-959 ◽  
Author(s):  
Régine Trébossen ◽  
Bernard Bendriem ◽  
Maria-Joao Ribeiro ◽  
Anne Fontaine ◽  
Vincent Frouin ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Scatter Correction ◽  
Three Dimensional ◽  
Input Function ◽  
Graphical Analysis ◽  
Emission Tomography ◽  
Data Sets ◽  
Positron Emission ◽  
3D Pet ◽  
Dopa Uptake

Three-dimensional (3D) positron emission tomography (PET) is attractive for [18F]fluoro-DOPA studies, since the sensitivity improvement is maximal for radioactive sources located in central planes, which is usually the case for the human striata. However, the image quantitation in that mode must be assessed because of the nearly threefold increase in scattered coincidences. We report the results of [18F]fluoro-DOPA studies performed on six normal volunteers. Each one was scanned in the 3D and two-dimensional(2D) modes on the same tomograph. The quantitation in the 3D and 2D modes was compared for a Patlak graphical analysis with the occipital counts as the input function (Ki) and a striatooccipital ratio analysis. We find that, in 3D PET, a scatter correction is required to preserve the same quantitation as in 2D PET. When the 3D data sets are corrected for scatter, the quantitation of the [18F]fluoro-DOPA uptake, using the Patlak analysis, is similar in the 2D and 3D acquisition modes. Conversely, analysis of the striatooccipital ratio leads to higher values in 3D PET because of a better in-plane resolution. Finally, using the 3D mode, the dose injected to the subjects can be reduced by a factor greater than 1.5 without any loss in accuracy compared to the 2D mode.

Positron Emission Tomography [15O]Water Studies with Short InterScan Interval for Single-Subject and Group Analysis: Influence of Background Subtraction

1998 ◽  
Vol 18 (4) ◽  
pp. 433-444 ◽  
Author(s):  
Jolanta Chmielowska ◽  
Robert C. Coghill ◽  
Jose-Marie Maisog ◽  
Richard E. Carson ◽  
Peter Herscovitch ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Group Analysis ◽  
Normal Subjects ◽  
Brain Regions ◽  
Emission Tomography ◽  
Single Subject ◽  
Data Sets ◽  
Positron Emission ◽  
Group Data ◽  
Residual Radioactivity

Use of short interscan interval [15O]water positron emission tomography (PET) studies reduces the overall study duration and may allow an increased number of scans for single-subject analysis of unique cases (e.g., stroke). The purpose of this study was to examine how subtraction of residual radioactivity from the previous injection (corrected scan) compared to nonsubtraction (uncorrected scan) in a PET short interscan interval (6 minutes) study affects single-subject and group data analysis using a motor activation task. Two currently widely used analytic strategies, Worsley's method and the SPM technique, were applied. Excellent agreement between activation maps obtained from corrected and uncorrected data sets was obtained both in single-subject analyses performed on data sets from the six normal subjects and three stroke (subcortical infarct) patients, and in group analysis (six normal subjects) within a particular statistical method. The corrected and uncorrected data were very similar in the (1) number of activated brain regions; (2) size of clusters of activated brain voxels; (3) Talairach coordinates of the activated region; and (4) t or Z value of the peak intensity for every significantly activated motor brain structure (both for large activations such as in motor cortex and small activations such as in putamen and thalamus). [15O]Water PET data obtained with a short interscan interval (6 minutes) produce similar results whether or not the background is subtracted. Thus, if injection dose and timing are constant, one can achieve the advantage of a short interscan interval without the added complexity of correcting for background radioactivity.

Positron Emission Tomography of Cocaine Binding Sites on the Dopamine Transporter

1994 ◽  
Author(s):  
Bertha K. Madras ◽  
◽  
David R. Elmaleh ◽  
Peter C. Meltzer ◽  
Anna Y. Liung ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Dopamine Transporter ◽  
Binding Sites ◽  
Emission Tomography ◽  
Positron Emission
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