Characterization of plasmon-resonant gold nanorods as near-infrared optical contrast agents investigated using a double-integrating sphere system

2005 ◽  
Author(s):  
Amy Oldenburg ◽  
Daniel A. Zweifel ◽  
Chenyang Xu ◽  
Alexander Wei ◽  
Stephen A. Boppart
Keyword(s):  
Contrast Agents ◽  
Gold Nanorods ◽  
Near Infrared ◽  
Integrating Sphere ◽  
Optical Contrast ◽  
Optical Contrast Agents

scholarly journals Optical Scattering Properties of Intralipid Phantom in Presence of Encapsulated Microbubbles

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Homa Assadi ◽  
Raffi Karshafian ◽  
Alexandre Douplik
Keyword(s):  
Contrast Agents ◽  
Volume Concentration ◽  
Optical Scattering ◽  
Imaging Systems ◽  
Integrating Sphere ◽  
Optical Contrast ◽  
Optical Contrast Agents ◽  
Diagnostic Modalities ◽  
Total Transmittance ◽  
Potential Use

In imaging, contrast agents are utilized to enhance sensitivity and specificity of diagnostic modalities. In ultrasound imaging, microbubbles (MBs)—a gas-core shell-encapsulated agent—are used clinically as contrast agents. The working hypothesis of this study is that microbubbles can be employed as an intravascular contrast agent in optical imaging systems. In this work, the interaction of light and microbubbles in a turbid medium (intralipid) was investigated, particularly, the effect of MBs on the reduced scattering and absorption coefficients. Diffuse reflectance (DR) and total transmittance (TT) measurements of highly scattering intralipid suspension (0.5–5%) were measured using spectroscopic integrating sphere system in the absence and presence of Definity microbubbles. The optical properties were computed using the inverse adding doubling (IAD) software. The presence of microbubbles increased DR and decreased TT of intralipid phantoms. In the presence of MBs (0.5% volume concentration), the reflectance of the intralipid phantom increased from 35% to 100%. The reduced scattering coefficient increased significantly (30%) indicating potential use of MBs as optical contrast agents in light based modalities.

scholarly journals Synthesis, functionalization and characterization of rod-shaped gold nanoparticles as potential optical contrast agents

2007 ◽  
Author(s):  
R.G. Rayavarapu ◽  
W. Petersen ◽  
S. Le Gac ◽  
C. Ungureanu ◽  
T.G. van Leeuwen ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Contrast Agents ◽  
Optical Contrast ◽  
Optical Contrast Agents

scholarly journals Synthesis, functionalization, and characterization of rod-shaped gold nanoparticles as potential optical contrast agents

2007 ◽  
Author(s):  
R. G. Rayavarapu ◽  
W. Petersen ◽  
S. Le Gac ◽  
C. Ungureanu ◽  
T. G. van Leeuwen ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Contrast Agents ◽  
Optical Contrast ◽  
Optical Contrast Agents

Cyanine Dyes as Optical Contrast Agents for Ophthalmological Surgery

2011 ◽  
Vol 54 (11) ◽  
pp. 3903-3925 ◽  
Author(s):  
Heinz Langhals ◽  
Ana Varja ◽  
Peter Laubichler ◽  
Marcus Kernt ◽  
Kirsten Eibl ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Cyanine Dyes ◽  
Optical Contrast ◽  
Optical Contrast Agents

Peptide-based optical contrast agents for targeting of intestinal malignancies

2007 ◽  
Author(s):  
Niels Röckendorf ◽  
Jürgen Helfmann ◽  
Naho Fujimoto ◽  
Katrin Wehry ◽  
Mario Bürger ◽  
...  
Keyword(s):  
Contrast Agents ◽  
Optical Contrast ◽  
Optical Contrast Agents
Sign in / Sign up

Export Citation Format

Share Document