New highly efficient two-photon fluorescent dyes

2004 ◽  
Author(s):  
Kevin D. Belfield ◽  
Alma R. Morales ◽  
Sheng Yao ◽  
Allyn Brice ◽  
Joel M. Hales ◽  
...  
Keyword(s):  
Fluorescent Dyes ◽  
Two Photon ◽  
Highly Efficient

Novel 2,1,3-Benzothiadiazole-Based Red-Fluorescent Dyes with Enhanced Two-Photon Absorption Cross-Sections

2006 ◽  
Vol 12 (8) ◽  
pp. 2303-2317 ◽  
Author(s):  
Shin-ichiro Kato ◽  
Taisuke Matsumoto ◽  
Motoyuki Shigeiwa ◽  
Hideki Gorohmaru ◽  
Shuuichi Maeda ◽  
...  
Keyword(s):  
Cross Sections ◽  
Fluorescent Dyes ◽  
Photon Absorption ◽  
Absorption Cross ◽  
Two Photon Absorption ◽  
Two Photon

scholarly journals Highly efficient singlet oxygen generation, two-photon photodynamic therapy and melanoma ablation by rationally designed mitochondria-specific near-infrared AIEgens

2020 ◽  
Vol 11 (9) ◽  
pp. 2494-2503 ◽  
Author(s):  
Zheng Zheng ◽  
Haixiang Liu ◽  
Shaodong Zhai ◽  
Haoke Zhang ◽  
Guogang Shan ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Near Infrared ◽  
Molecular Engineering ◽  
Photon Absorption ◽  
Oxygen Generation ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Singlet Oxygen Generation ◽  
Highly Efficient

Mitochondria-targeted photosensitizers with highly efficient singlet oxygen generation, bright near-infrared AIE and good two-photon absorption are obtained through ingenious molecular engineering for cancer cell-selective photodynamic therapy.

A two-photon AIE fluorophore as a photosensitizer for highly efficient mitochondria-targeted photodynamic therapy

2020 ◽  
Vol 44 (22) ◽  
pp. 9355-9364 ◽  
Author(s):  
Qunshou Kong ◽  
Boxuan Ma ◽  
Tao Yu ◽  
Cheng Hu ◽  
Gaocan Li ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Two Photon ◽  
Highly Efficient ◽  
Targeted Photodynamic Therapy

Nowadays, photodynamic therapy (PDT) has become an effective method for cancer therapy.

Bright and two-photon active red fluorescent dyes that selectively move back and forth between the mitochondria and nucleus upon changing the mitochondrial membrane potential

2018 ◽  
Vol 6 (45) ◽  
pp. 7396-7401 ◽  
Author(s):  
Hitomi Seki ◽  
Shozo Onishi ◽  
Naoya Asamura ◽  
Yasutaka Suzuki ◽  
Jun Kawamata ◽  
...  
Keyword(s):  
Membrane Potential ◽  
Mitochondrial Membrane Potential ◽  
Mitochondrial Membrane ◽  
Fluorescent Dyes ◽  
Two Photon

Pyrene-based two-photon active and bright red emitters that localize between the mitochondria and nucleus in response to changes in the mitochondrial membrane potential.

Fact and Artefact in Confocal Microscopy

1997 ◽  
Vol 11 (4) ◽  
pp. 433-441 ◽  
Author(s):  
T.F. Watson
Keyword(s):  
Fluorescent Dyes ◽  
Numerical Aperture ◽  
Two Photon ◽  
Maximum Resolution ◽  
Index Matching ◽  
Refractive Index Matching ◽  
A Cell ◽  
Investigative Technique ◽  
The Individual ◽  
Combining Information

High-resolution confocal microscopic images may be made of either the surface of a sample or beneath the surface. These images can be likened to optical tomograms, giving thin (> 0.35 μm) slices up to 200 μm below the surface of a transparent tissue: With microscopes running under normal conditions, the optical section thickness will be >1 μm and the effective penetration into enamel and dentin a maximum of 100 μm. For maximum resolution, high-quality, high-numerical-aperture objectives should be used. Refractive index matching of the lens immersion media and the substrate will avoid distortions of images in the optical axis. Such errors could occur when imaging a considerable distance (> 40 μm) into a cell containing water, with an oil immersion objective above the cover slip. Care should be taken in the interpretation of computerized z axis reconstructions made from serial optical sections: Their validity should be checked with equivalent views made with the sample oriented in the same direction as the reconstruction. The use of fluorescent dyes in microscopy is a very powerful investigative technique. It is important that the dyes used not be labile and that they be well-fixed to the materials being examined, or the images may indicate the dye distribution rather than the material to which it is "attached". Multiple labeling experiments must have crossover control experiments to verify the distribution of the individual dyes. Valuable information can often be gained by combining information from both reflection and fluorescence images. Two-photon laser excitation of dyes gives the potential for greater depth penetration and improved resolution.

Amino-Si-rhodamines: A new class of two-photon fluorescent dyes with intrinsic targeting ability for lysosomes

Biomaterials ◽  
2018 ◽  
Vol 158 ◽  
pp. 10-22 ◽  
Author(s):  
Hongxing Zhang ◽  
Jing Liu ◽  
Linfang Wang ◽  
Minjia Sun ◽  
Xiaohan Yan ◽  
...  
Keyword(s):  
Fluorescent Dyes ◽  
New Class ◽  
Two Photon ◽  
Targeting Ability
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