A Mueller polarimetric imaging system for biomedical applications

Author(s):  
Blandine Laude ◽  
Antonello De Martino ◽  
Gilles Le Naour ◽  
Catherine Genestie ◽  
Andre Nazac ◽  
...  
Author(s):  
B. Laude ◽  
A. De Martino ◽  
G. Le Naour ◽  
C. Genestie ◽  
A. Nazac ◽  
...  

Micromachines ◽  
2020 ◽  
Vol 11 (9) ◽  
pp. 861
Author(s):  
Elizabeth E. Niedert ◽  
Chenghao Bi ◽  
Georges Adam ◽  
Elly Lambert ◽  
Luis Solorio ◽  
...  

A microrobot system comprising an untethered tumbling magnetic microrobot, a two-degree-of-freedom rotating permanent magnet, and an ultrasound imaging system has been developed for in vitro and in vivo biomedical applications. The microrobot tumbles end-over-end in a net forward motion due to applied magnetic torque from the rotating magnet. By turning the rotational axis of the magnet, two-dimensional directional control is possible and the microrobot was steered along various trajectories, including a circular path and P-shaped path. The microrobot is capable of moving over the unstructured terrain within a murine colon in in vitro, in situ, and in vivo conditions, as well as a porcine colon in ex vivo conditions. High-frequency ultrasound imaging allows for real-time determination of the microrobot’s position while it is optically occluded by animal tissue. When coated with a fluorescein payload, the microrobot was shown to release the majority of the payload over a 1-h time period in phosphate-buffered saline. Cytotoxicity tests demonstrated that the microrobot’s constituent materials, SU-8 and polydimethylsiloxane (PDMS), did not show a statistically significant difference in toxicity to murine fibroblasts from the negative control, even when the materials were doped with magnetic neodymium microparticles. The microrobot system’s capabilities make it promising for targeted drug delivery and other in vivo biomedical applications.


2016 ◽  
Vol 21 (7) ◽  
pp. 076006 ◽  
Author(s):  
Rui Zhang ◽  
Liangliang Zhang ◽  
Tong Wu ◽  
Ruixue Wang ◽  
Shasha Zuo ◽  
...  

Sensors ◽  
2019 ◽  
Vol 19 (7) ◽  
pp. 1692 ◽  
Author(s):  
José A. Gutiérrez-Gutiérrez ◽  
Arturo Pardo ◽  
Eusebio Real ◽  
José M. López-Higuera ◽  
Olga M. Conde

Prototyping hyperspectral imaging devices in current biomedical optics research requires taking into consideration various issues regarding optics, imaging, and instrumentation. In summary, an ideal imaging system should only be limited by exposure time, but there will be technological limitations (e.g., actuator delay and backlash, network delays, or embedded CPU speed) that should be considered, modeled, and optimized. This can be achieved by constructing a multiparametric model for the imaging system in question. The article describes a rotating-mirror scanning hyperspectral imaging device, its multiparametric model, as well as design and calibration protocols used to achieve its optimal performance. The main objective of the manuscript is to describe the device and review this imaging modality, while showcasing technical caveats, models and benchmarks, in an attempt to simplify and standardize specifications, as well as to incentivize prototyping similar future designs.


2007 ◽  
Author(s):  
Keiji Umetani ◽  
Makito Kobatake ◽  
Akira Yamamoto ◽  
Takenori Yamashita ◽  
Shigeki Imai

2015 ◽  
Vol 52 (4) ◽  
pp. 1112-1128 ◽  
Author(s):  
George C. Giakos ◽  
Suman Shrestha ◽  
Tannaz Farrahi ◽  
Jeff Petermann ◽  
Aditi Deshpande ◽  
...  

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