Time-resolved diffuse reflectance and transmittance studies in tissue simulating phantoms: a comparison between theory and experiment

Author(s):  
Sten Madsen ◽  
Michael S. Patterson ◽  
Brian C. Wilson ◽  
Young D. Park ◽  
John D. Moulton ◽  
...  
1997 ◽  
Vol 410-411 ◽  
pp. 81-84 ◽  
Author(s):  
C. Brémard ◽  
G. Buntinx ◽  
G. Coustillier ◽  
G. Ginestet

Author(s):  
Justin Legleiter ◽  
Kathleen A. Burke ◽  
Elizabeth A. Yates

There is great interest in the application of proximal probe techniques to simultaneously image and measure mechancial properties of surfaces with nanoscale spatial resolution. There have been several innovations in generating time-resolved force interaction between the tip and surface while acquiring a tapping mode AFM image. These tip/sample forces contain information regarding mechanical properties of surfaces in an analogous fashion to a force curve experiment. Here, we demonstrate, via simulation, that the maximum and minimum tapping forces change with respect to the Young’s modulus and adhesiveness of a surface, but the roughness of the surfaces has no effect on the tapping forces. Using these changes in tapping forces, we determine the mechanical changes of a lipid membrane after exposure to a huntingtin exon1 (htt exon1) protein with an expanded polyglutamine (polyQ) domain. Expanded polyQ domains in htt is associated with Huntington’s disease, a genetic neurodegenerative disorder. The htt exon1 protein caused regions of increased surface roughness to appear in the lipid membrane, and these areas were associated with decreased elasticity and adhesion to the AFM probe.


2011 ◽  
Vol 20 (1) ◽  
pp. 283 ◽  
Author(s):  
M. Mazurenka ◽  
A. Jelzow ◽  
H. Wabnitz ◽  
D. Contini ◽  
L. Spinelli ◽  
...  

2004 ◽  
Vol 6 (4) ◽  
pp. 193-198 ◽  
Author(s):  
J. P. Da Silva ◽  
L. F. Vieira Ferreira

The photochemistry of biphenyl (BP) was studied on two model solid supports, silicalite and cellulose, using time resolved diffuse reflectance techniques and product degradation analysis. The results showed that the photochemical behaviour of BP depends on the solid support. Ground state absorption spectra indicated a near planar configuration in the ground state. BP triplet state was the only species detected on cellulose, while the radical cation(BP•+)was observed in silicalite. BP is relatively stable in both supports. Prolonged irradiations in cellulose lead to the formation of the three monohydroxybiphenyls, while in silicalite photooxidation products prevailed.


2021 ◽  
Vol 281 ◽  
pp. 119479
Author(s):  
Shaoxiong He ◽  
Chunyang Zhai ◽  
Mamoru Fujitsuka ◽  
Sooyeon Kim ◽  
Mingshan Zhu ◽  
...  

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