Luminescence image analyzers for biological microchips

A microcomputer-based measuring device for biological research

Canadian Journal of Zoology ◽

10.1139/z81-221 ◽

1981 ◽

Vol 59 (8) ◽

pp. 1611-1614 ◽

Cited By ~ 51

Author(s):

W. Gary Sprules ◽

L. Blair Holtby ◽

Gerald Griggs

Keyword(s):

Data Storage ◽

Biological Research ◽

Fish Scale ◽

Body Proportions ◽

Measuring Device ◽

Storage And Retrieval ◽

Phytoplankton Size ◽

Image Analyzers ◽

Associated Data ◽

Size Data

As an inexpensive, more versatile alternative to the Coulter counter and image analyzers for the acquisition of size data in biological research, a semiautomated measuring device with associated data storage and retrieval capabilities has been developed. It can be used for measurement of such diverse characters as zooplankton body size and helmet lengths, phytoplankton size, fish scale measurements, fish egg diameters, and general taxonomic features such as body proportions and inter-setule distances. Any organism, or part thereof, which can be scaled to the device's range of approximately 1–7 cm can be quickly and accurately counted and (or) measured.

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Spatial Reconstruction of the Bone Trabecular Network. A Simple Algorithm for the Leitz TAS+ and Related Image Analyzers

Journal of Histotechnology ◽

10.1179/his.1988.11.3.133 ◽

1988 ◽

Vol 11 (3) ◽

pp. 133-136 ◽

Cited By ~ 1

Author(s):

Daniel Chappard ◽

Muriel Petitjean ◽

Sabine Palle ◽

Laurence Vico ◽

Christian Alexandre

Keyword(s):

Simple Algorithm ◽

Spatial Reconstruction ◽

Trabecular Network ◽

Image Analyzers

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Optical properties of fluorochromes promising for use in biological microchips

Molecular Biology ◽

10.1007/bf02759650 ◽

2000 ◽

Vol 34 (2) ◽

pp. 266-271 ◽

Cited By ~ 5

Author(s):

E. Yu. Kotova ◽

E. Ya. Kreindlin ◽

V. E. Barsky ◽

A. D. Mirzabekov

Keyword(s):

Optical Properties ◽

Biological Microchips

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Analysis of NAT2 point mutations with biological microchips

Molecular Biology ◽

10.1134/s0026893307040206 ◽

2007 ◽

Vol 41 (4) ◽

pp. 656-664 ◽

Cited By ~ 2

Author(s):

Zh. M. Kozhekbaeva ◽

A. S. Glotov ◽

O. A. Gra ◽

I. V. Goldenkova-Pavlova ◽

S. A. Bruskin ◽

...

Keyword(s):

Point Mutations ◽

Biological Microchips

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Biological microchips – a new level of laboratory research

Analytics ◽

10.22184/2227-572x.2017.36.5.76.86 ◽

2017 ◽

pp. 76-86

Author(s):

O.V. Lastochkina ◽

P.V. Gorelov

Keyword(s):

Laboratory Research ◽

Biological Microchips

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Luminescence video analyzer of biological microchips

Journal of Optical Technology ◽

10.1364/jot.73.000864 ◽

2006 ◽

Vol 73 (12) ◽

pp. 864

Author(s):

L. S. Agroskin ◽

P. S. Parfenov ◽

I. Ya. Barskiĭ ◽

Yu. M. Voronin ◽

V. E. Barskiĭ

Keyword(s):

Biological Microchips

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Maximizing Precision in Quantitative Autoradiographic Determination of Tissue Tracer Concentration Using Exposure Optimization

Journal of Cerebral Blood Flow & Metabolism ◽

10.1038/jcbfm.1986.85 ◽

1986 ◽

Vol 6 (4) ◽

pp. 499-504 ◽

Cited By ~ 5

Author(s):

James L. Lear

Keyword(s):

Blood Flow ◽

Cerebral Blood Flow ◽

Optical Density ◽

Digital Image ◽

Precise Determination ◽

Tracer Concentration ◽

Image Analyzers

The relationships between tissue tracer concentrations, length of time of tissue contact with film, and the darkness of resulting autoradiographic images were explored. Operational equations were then developed relating ranges of film darkening to the ranges of tracer concentration contained within the sections. These equations were solved and used to define ranges of optical density that are optimal for precise determination of tracer concentration using digital image analyzers. The solutions indicated that optimal optical densities are a function of the range of tracer concentrations in the sections. For autoradiograms of typical cerebral blood flow and metabolism tracers, exposure should be controlled to produce images that are significantly less dark than what is generally considered pleasing to the eye.

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