Modulation of Photofrin II accumulation in C6 glioma cells by stimulation of beta-adrenergic receptors

1997 ◽  
Author(s):  
Anna C. Croce ◽  
V. Mares ◽  
V. Lisa ◽  
D. Krajci ◽  
Giovanni F. Bottiroli
1983 ◽  
Vol 97 (5) ◽  
pp. 1538-1543 ◽  
Author(s):  
C Hertel ◽  
M Staehelin

The reappearance of beta-adrenergic receptors in C6-glioma cells after desensitization with isoproterenol was studied using the antagonist [3H]CGP-12177. Reappearance had the following properties: (a) it occurred in intact cells only, (b) it was temperature dependent, (c) it required an Na+/H+ gradient, low intracellular Ca2+ activity, and (d) it required ATP, and (e) intact lysosomes. The results suggest endocytosis and recycling of the beta-adrenergic receptor after agonist treatment.


1993 ◽  
Vol 268 (12) ◽  
pp. 8980-8989
Author(s):  
N. Charpentier ◽  
L. Prézeau ◽  
J. Carrette ◽  
R. Bertorelli ◽  
G. Le Cam ◽  
...  

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