New 1000x1000 frame transfer CCD camera for high-speed high-fidelity digital imaging

1997 ◽  
Author(s):  
David J. Litwiller
Keyword(s):  
Digital Imaging ◽  
High Speed ◽  
Ccd Camera ◽  
High Fidelity

High-speed brightfield 3-D imaging and 3-D image analysis of thick and overlapped cell clusters in cytological preparations

1994 ◽  
Vol 52 ◽  
pp. 218-219
Author(s):  
Robert W. Mackin
Keyword(s):  
Image Analysis ◽  
High Speed ◽  
Three Dimensional ◽  
Image Data ◽  
Ccd Camera ◽  
Objective Lens ◽  
Array Processor ◽  
Vaginal Smears ◽  
Low Contrast ◽  
Computer Controlled

This paper presents two advances towards the automated three-dimensional (3-D) analysis of thick and heavily-overlapped regions in cytological preparations such as cervical/vaginal smears. First, a high speed 3-D brightfield microscope has been developed, allowing the acquisition of image data at speeds approaching 30 optical slices per second. Second, algorithms have been developed to detect and segment nuclei in spite of the extremely high image variability and low contrast typical of such regions. The analysis of such regions is inherently a 3-D problem that cannot be solved reliably with conventional 2-D imaging and image analysis methods.High-Speed 3-D imaging of the specimen is accomplished by moving the specimen axially relative to the objective lens of a standard microscope (Zeiss) at a speed of 30 steps per second, where the stepsize is adjustable from 0.2 - 5μm. The specimen is mounted on a computer-controlled, piezoelectric microstage (Burleigh PZS-100, 68/μm displacement). At each step, an optical slice is acquired using a CCD camera (SONY XC-11/71 IP, Dalsa CA-D1-0256, and CA-D2-0512 have been used) connected to a 4-node array processor system based on the Intel i860 chip.

Five-Dimensional Microscopy using Widefield-Deconvolution: Practical Considerations and Biological Applications

1996 ◽  
Vol 54 ◽  
pp. 268-269
Author(s):  
W.F. Marshall ◽  
K. Oegema ◽  
J. Nunnari ◽  
A.F. Straight ◽  
D.A. Agard ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
High Speed ◽  
Laser Scanning ◽  
Ccd Camera ◽  
Image Plane ◽  
Time Lapse ◽  
Laser Scanning Confocal Microscopy ◽  
Three Dimensions ◽  
Excitation Light ◽  
Cooled Ccd

The ability to image cells in three dimensions has brought about a revolution in biological microscopy, enabling many questions to be asked which would be inaccessible without this capability. There are currently two major methods of three dimensional microscopy: laser-scanning confocal microscopy and widefield-deconvolution microscopy. The method of widefield-deconvolution uses a cooled CCD to acquire images from a standard widefield microscope, and then computationally removes out of focus blur. Using such a scheme, it is easy to acquire time-lapse 3D images of living cells without killing them, and to do so for multiple wavelengths (using computer-controlled filter wheels). Thus, it is now not only feasible, but routine, to perform five dimensional microscopy (three spatial dimensions, plus time, plus wavelength).Widefield-deconvolution has several advantages over confocal microscopy. The two main advantages are high speed of acquisition (because there is no scanning, a single optical section is acquired at a time by using a cooled CCD camera) and the use of low excitation light levels Excitation intensity can be much lower than in a confocal microscope for three reasons: 1) longer exposures can be taken since the entire 512x512 image plane is acquired in parallel, so that dwell time is not an issue, 2) the higher quantum efficiently of a CCD detect over those typically used in confocal microscopy (although this is expected to change due to advances in confocal detector technology), and 3) because no pinhole is used to reject light, a much larger fraction of the emitted light is collected. Thus we can typically acquire images with thousands of photons per pixel using a mercury lamp, instead of a laser, for illumination. The use of low excitation light is critical for living samples, and also reduces bleaching. The high speed of widefield microscopy is also essential for time-lapse 3D microscopy, since one must acquire images quickly enough to resolve interesting events.

The bright future of digital imaging in scanning electron microscopy

1993 ◽  
Vol 51 ◽  
pp. 768-769
Author(s):  
M. T. Postek ◽  
A. E. Vladar
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Digital Imaging ◽  
High Speed ◽  
High Performance ◽  
Mass Storage ◽  
Analog To Digital ◽  
Central Processing ◽  
Digital Imaging Technology ◽  
Scanning Electron

One of the major advancements applied to scanning electron microscopy (SEM) during the past 10 years has been the development and application of digital imaging technology. Advancements in technology, notably the availability of less expensive, high-density memory chips and the development of high speed analog-to-digital converters, mass storage and high performance central processing units have fostered this revolution. Today, most modern SEM instruments have digital electronics as a standard feature. These instruments, generally have 8 bit or 256 gray levels with, at least, 512 × 512 pixel density operating at TV rate. In addition, current slow-scan commercial frame-grabber cards, directly applicable to the SEM, can have upwards of 12-14 bit lateral resolution permitting image acquisition at 4096 × 4096 resolution or greater. The two major categories of SEM systems to which digital technology have been applied are:In the analog SEM system the scan generator is normally operated in an analog manner and the image is displayed in an analog or "slow scan" mode.

scholarly journals Getting High: High Fidelity Simulation of High Granularity Calorimeters with High Speed

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Erik Buhmann ◽  
Sascha Diefenbacher ◽  
Engin Eren ◽  
Frank Gaede ◽  
Gregor Kasieczka ◽  
...  
Keyword(s):  
Particle Physics ◽  
High Speed ◽  
Deep Neural Networks ◽  
High Fidelity ◽  
High Fidelity Simulation ◽  
Physical Processes ◽  
Electromagnetic Showers ◽  
Information Bottleneck ◽  
First Time ◽  
Processing Network

AbstractAccurate simulation of physical processes is crucial for the success of modern particle physics. However, simulating the development and interaction of particle showers with calorimeter detectors is a time consuming process and drives the computing needs of large experiments at the LHC and future colliders. Recently, generative machine learning models based on deep neural networks have shown promise in speeding up this task by several orders of magnitude. We investigate the use of a new architecture—the Bounded Information Bottleneck Autoencoder—for modelling electromagnetic showers in the central region of the Silicon-Tungsten calorimeter of the proposed International Large Detector. Combined with a novel second post-processing network, this approach achieves an accurate simulation of differential distributions including for the first time the shape of the minimum-ionizing-particle peak compared to a full Geant4 simulation for a high-granularity calorimeter with 27k simulated channels. The results are validated by comparing to established architectures. Our results further strengthen the case of using generative networks for fast simulation and demonstrate that physically relevant differential distributions can be described with high accuracy.

Vocal Fold Vibratory Characteristics in Normal Female Speakers From High-Speed Digital Imaging

2012 ◽  
Vol 26 (2) ◽  
pp. 239-253 ◽  
Author(s):  
Kartini Ahmad ◽  
Yuling Yan ◽  
Diane M. Bless
Keyword(s):  
Digital Imaging ◽  
Vocal Fold ◽  
High Speed ◽  
Normal Female

Towards A Multi-FPGA Infrared Simulator

2007 ◽  
Vol 4 (4) ◽  
pp. 343-355 ◽  
Author(s):  
Vinay Sriram ◽  
David Kearney
Keyword(s):  
Homeland Security ◽  
Reconfigurable Computing ◽  
High Speed ◽  
High Performance ◽  
Large Scale ◽  
Computation Time ◽  
Ccd Camera ◽  
Hardware Acceleration ◽  
Limiting Factor ◽  
Scene Simulation

High speed infrared (IR) scene simulation is used extensively in defense and homeland security to test sensitivity of IR cameras and accuracy of IR threat detection and tracking algorithms used commonly in IR missile approach warning systems (MAWS). A typical MAWS requires an input scene rate of over 100 scenes/second. Infrared scene simulations typically take 32 minutes to simulate a single IR scene that accounts for effects of atmospheric turbulence, refraction, optical blurring and charge-coupled device (CCD) camera electronic noise on a Pentium 4 (2.8GHz) dual core processor [7]. Thus, in IR scene simulation, the processing power of modern computers is a limiting factor. In this paper we report our research to accelerate IR scene simulation using high performance reconfigurable computing. We constructed a multi Field Programmable Gate Array (FPGA) hardware acceleration platform and accelerated a key computationally intensive IR algorithm over the hardware acceleration platform. We were successful in reducing the computation time of IR scene simulation by over 36%. This research acts as a unique case study for accelerating large scale defense simulations using a high performance multi-FPGA reconfigurable computer.

scholarly journals Relation between Voice Quality and Pathological Vibratory Patterns Using High-Speed Digital Imaging.

1999 ◽  
Vol 102 (3) ◽  
pp. 354-367 ◽  
Author(s):  
Mamiko Miyaji ◽  
Yoshitake Iwamoto ◽  
Makoto Oda ◽  
Seiji Niimi
Keyword(s):  
Digital Imaging ◽  
High Speed ◽  
Voice Quality

Estimation of glottal area function using stereo-endoscopic high-speed digital imaging

2010 ◽  
Author(s):  
Hiroshi Imagawa ◽  
Ken-Ichi Sakakibara ◽  
Isao T. Tokuda ◽  
Mamiko Otsuka ◽  
Niro Tayama
Keyword(s):  
Digital Imaging ◽  
High Speed ◽  
Area Function

A Two-Dimensional Surface Profile Imaging Technique Based on Heterodyne Interferometer

2005 ◽  
Vol 295-296 ◽  
pp. 477-482
Author(s):  
K.W. Wang ◽  
Z.J. Cai ◽  
Li Jiang Zeng
Keyword(s):  
High Speed ◽  
Imaging Technique ◽  
Surface Profile ◽  
Ccd Camera ◽  
Measurement Range ◽  
Interference Signal ◽  
Two Dimensional ◽  
Step Method ◽  
Heterodyne Interferometer ◽  
Dimensional Surface

A two-dimensional surface profile imaging technique based on heterodyne interferometer is proposed. A piezo translator vibrated grating is used to generate a heterodyne signal. A high speed CCD camera is used to extract the interference signal using a five step method. The uncertainty in the displacement measurement is approximately 0.035 µm within a measurement range of 1.7 µm, confirming the two dimensional heterodyne interferometer is valid for measuring the surface profile. The method is also available for low coherence heterodyne interferometer due to the optical frequency shifts caused by the vibration of grating independent on the wavelength.

A High Fidelity Roll Dependent Aerodynamic Model for a Long Range, High Speed Missile

2022 ◽  
Author(s):  
Bradley T. Burchett ◽  
Justin L. Paul ◽  
Joseph D. Vasile ◽  
Joshua Bryson
Keyword(s):  
Long Range ◽  
High Speed ◽  
High Fidelity ◽  
Aerodynamic Model
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