Effect of alkaline environment on Ti3C2Tx-MXene etching

2021 ◽  
Author(s):  
Yunhan Sun ◽  
qingxiu jia ◽  
Jian Yang
Keyword(s):  
Alkaline Environment

Synthesis, Characterization and in-vitro drug release studies of a macromolecular prodrug of Didanosine.

2010 ◽  
Vol 2 (2) ◽  
Author(s):  
Neeraj Agrawal ◽  
M.J. Chandrasekar ◽  
U.V. Sara ◽  
Rohini A.
Keyword(s):  
Drug Release ◽  
Drug Level ◽  
Drug Release Profile ◽  
Sustained Drug Release ◽  
In Vitro Drug Release ◽  
Alkaline Environment ◽  
Stomach Acid ◽  
Release Studies ◽  
Macromolecular Prodrug

A macromolecular prodrug of didanosine (ddI) for oral administration was synthesized and evaluated for in-vitro drug release profile. Didanosine was first coupled to 2-hydroxy ethyl methacrylate (HEMA) through a succinic spacer to form HEMA-Suc-ddI monomeric conjugate which was subsequently polymerized to yield Poly(HEMA-Suc-ddI) conjugate. The structures of the synthesized compounds were characterized by FT-IR, Mass and 1H-NMR spectroscopy. The prodrug was subjected for in-vitro drug release studies in buffers of pH 1.2 and 7.4 mimicking the upper and lower GIT. The results showed that the drug release from the polymeric backbone takes place in a sustained manner over a period of 24 h and the amount of drug released was comparatively higher at pH 7.4 indicating that the drug release takes place predominantly at the alkaline environment of the lower GIT rather than at the acidic environment of the upper GIT. This pH dependent sustained drug release behavior of the prodrug may be capable of reducing the dose limiting toxicities by maintaining the plasma drug level within the therapeutic range and increasing t1/2 of ddI. Moreover, the bioavailability of the drug should be improved as the prodrug releases ddI predominantly in the alkaline environment which will reduce the degradation of ddI in the stomach acid.

Facile synthesis of hexagonal α-Co(OH)2 nanosheets and their superior activity in selective reduction of nitrocompounds

2021 ◽  
Author(s):  
Jiahui Guo ◽  
Xueqing Feng ◽  
Songrui Wang ◽  
Qikang Wu ◽  
Shanshan Lv ◽  
...  
Keyword(s):  
Cetyltrimethylammonium Bromide ◽  
Selective Reduction ◽  
Cobalt Hydroxide ◽  
Facile Synthesis ◽  
Alkaline Environment ◽  
Favorable Conditions

A novel hexagonal α-cobalt hydroxide nanosheets are synthesized through 2-methylimidazole induced hydrolysis strategy with cetyltrimethylammonium bromide (CTAB) as surfactant. The weak alkaline environment provides favorable conditions for the formation of...

scholarly journals Studies on separation and properties of lumbrokinase in Pheretima praepinguis

2016 ◽  
Vol 11 ◽  
pp. S106-S109
Author(s):  
Tang Mei ◽  
Liu Cao ◽  
Liang Zi ◽  
Gong Mingfu ◽  
Hu Die
Keyword(s):  
High Temperature ◽  
Enzymatic Activity ◽  
Enzymatic Properties ◽  
Temperature Adaptation ◽  
Plate Method ◽  
Salting Out ◽  
Effect Of Ph ◽  
Alkaline Environment ◽  
Method Effect ◽  
Wide Range

The purpose of this study was to separate lumbrokinase in Pheretima praepinguis and examine its enzymatic properties. With P. praepinguis as material, lumbrokinase was separated with the salting out method. Lumbrokinase activity was measured with casein medium plate method. Effect of pH and temperature on lumbrokinase activity was studied. Results of lumbrokinase separated from P. praepinguis was relatively high. Lumbrokinase activity in neutral or slightly alkaline environment was higher. Lumbrokinase had tolerance ability to high temperature, with highly enzymatic activity under 60°C and wide range of temperature adaptation. 

scholarly journals Complexing power of hydro-soluble degradation products from γirradiated polyvinylchloride: influence on Eu(OH)3(s) solubility and Eu(III) speciation in neutral to alkaline environment

2017 ◽  
Vol 105 (8) ◽  
Author(s):  
Pascal E. Reiller ◽  
Elodie Fromentin ◽  
Muriel Ferry ◽  
Adeline Dannoux-Papin ◽  
Hawa Badji ◽  
...  
Keyword(s):  
Oxidation State ◽  
Alkaline Hydrolysis ◽  
Degradation Products ◽  
Alkaline Environment ◽  
Hydrolysis Of

AbstractThe complexing power of hydrosoluble degradation products (HDPs) from an alkaline hydrolysis of a 10 MGy γ-irradiated polyvinylchloride is studied. The complexation of Eu(III), as an analogue of lanthanide and actinide radionuclides at their +III oxidation state for oxygen containing functions, is evidenced both from the increasing of Eu(OH)

scholarly journals Synergistic Excitation Mechanism of CaO-SiO2-Al2O3-SO3 Quaternary Active Cementitious System

2021 ◽  
Vol 8 ◽  
Author(s):  
Fusheng Niu ◽  
Yukun An ◽  
Jinxia Zhang ◽  
Wen Chen ◽  
Shengtao He
Keyword(s):  
Blast Furnace ◽  
Blast Furnace Slag ◽  
Steel Slag ◽  
Cementitious Materials ◽  
Test Block ◽  
Hydration Reaction ◽  
Alkaline Environment ◽  
Granulated Blast Furnace Slag ◽  
Cementitious System ◽  
Furnace Slag

In this study, the influence of steel slag (SS) content on the strength of the cementitious materials was investigated. The quaternary active cementitious material (CaO-SiO2-Al2O3-SO3) was prepared using various proportions of steel slag (SS), granulated blast furnace slag (BFS), and desulfurized gypsum (DG). The mechanism of synergistic excitation hydration of the cementitious materials was examined using various techniques such as X-ray diffraction (XRD), scanning electron microscopy (SEM) and Fourier transform infrared spectrometry (FTIR). The strength of the mortar test block was initially increased and decreased later with the increase of the SS content. Mortar test block with 20% steel slag, 65% granulated blast furnace slag, and 15% desulfurized gypsum with 0.35 water-binder ratio showed the highest compressive strength of 57.3 MPa on 28 days. The free calcium oxide (f-CaO) in the SS reacted with water and produced calcium hydroxide (Ca(OH)2) which created an alkaline environment. Under the alkaline environment, the alkali-activated reaction occurred with BFS. In the early stage of hydration reaction, calcium silicate hydrate (C-S-H) gel and fibrous hydration product ettringite (AFt) crystals were formed, which provided early strength to the cementitious materials. As the hydration reaction progressed, the interlocked growth of C-S-H gel and AFt crystals continued and promoted the increase of the strength of the cementitious system.

Photocatalytic Oxidation of Arsenic(III) by Hydrothermal Synthesized TiO2 Loaded on Activated Carbon Fiber

2013 ◽  
Vol 631-632 ◽  
pp. 176-180 ◽  
Author(s):  
Ying Hao Xie ◽  
Zhan Chang Pan ◽  
Zhi Gang Wei ◽  
Wei Lin Feng ◽  
Jun Hui Zuo ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Activated Carbon ◽  
Carbon Fiber ◽  
Hydrothermal Method ◽  
Photocatalytic Oxidation ◽  
Catalytic Efficiency ◽  
Activated Carbon Fiber ◽  
Acidic Environment ◽  
Effect Of Ph ◽  
Alkaline Environment

In this paper, nano TiO2 loaded on activated carbon fiber(ACF) was prepared by hydrothermal method as TiO2/ACF photocatalytic.The material crystal structure, the superficial appearance of catalyst, were analyzed and measured by XRD and SEM images.Moreover, it used for photocatalytic oxidation As(Ⅲ).The effect of pH on the oxidation of As(Ⅲ) was studied. The oxidation of As(Ⅲ) efficiency increasing markedly with pH, and the catalytic efficiency is much higher in the alkaline environment than in the acidic environment.

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