Lateral resolution and imaging depth of shifted position-diffuse reflectance imaging

2021 ◽  
Author(s):  
Moritz Spath ◽  
Martin Hohmann ◽  
Florian Stelzle ◽  
Florian Klampfl
Keyword(s):  
Diffuse Reflectance ◽  
Lateral Resolution ◽  
Imaging Depth ◽  
Diffuse Reflectance Imaging

scholarly journals Towards shifted position-diffuse reflectance imaging of anatomically correctly scaled human microvasculature

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Moritz Späth ◽  
Martin Hohmann ◽  
Clemens Roider ◽  
Benjamin Lengenfelder ◽  
Florian Stelzle ◽  
...  
Keyword(s):  
Diffuse Reflectance ◽  
Optical Methods ◽  
Reference Image ◽  
Core Diameter ◽  
Non Invasive ◽  
Evaluation Algorithm ◽  
Examination Methods ◽  
Illumination Wavelength ◽  
Diffuse Reflectance Imaging ◽  
Reflectance Data

Abstract Due to significant advantages, the trend in the field of medical technology is moving towards minimally or even non-invasive examination methods. In this respect, optical methods offer inherent benefits, as does diffuse reflectance imaging (DRI). The present study attempts to prove the suitability of DRI—when implemented alongside a suitable setup and data evaluation algorithm—to derive information from anatomically correctly scaled human capillaries (diameter: $$10\,\upmu \hbox {m}$$ 10 μ m , length: $$45\,\upmu \hbox {m}$$ 45 μ m ) by conducting extensive Monte–Carlo simulations and by verifying the findings through laboratory experiments. As a result, the method of shifted position-diffuse reflectance imaging (SP-DRI) is established by which average signal modulations of up to 5% could be generated with an illumination wavelength of $$\lambda =424\,\hbox {nm}$$ λ = 424 nm and a core diameter of the illumination fiber of $$50\,\upmu \hbox {m}$$ 50 μ m . No reference image is needed for this technique. The present study reveals that the diffuse reflectance data in combination with the SP-DRI normalization are suitable to localize human capillaries within turbid media.

scholarly journals Non-contact time-resolved diffuse reflectance imaging at null source-detector separation

2011 ◽  
Vol 20 (1) ◽  
pp. 283 ◽  
Author(s):  
M. Mazurenka ◽  
A. Jelzow ◽  
H. Wabnitz ◽  
D. Contini ◽  
L. Spinelli ◽  
...  
Keyword(s):  
Contact Time ◽  
Diffuse Reflectance ◽  
Time Resolved ◽  
Diffuse Reflectance Imaging

In vivo 783-channel diffuse reflectance imaging system and its application

2007 ◽  
Vol 46 (23) ◽  
pp. 5991 ◽  
Author(s):  
Joon-Mo Yang ◽  
Yong-Hui Han ◽  
Gilwon Yoon ◽  
Byung Soo Ahn ◽  
Byung-Cheon Lee ◽  
...  
Keyword(s):  
Diffuse Reflectance ◽  
Imaging System ◽  
Diffuse Reflectance Imaging
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