Application of Raman spectroscopy for the detection of colored tattoo inks in tissues: preliminary phantom study

2021 ◽  
Author(s):  
Filip Sadura ◽  
Maciej S. Wrobel ◽  
Katarzyna Karpienko
Materials ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3147
Author(s):  
Filip Sadura ◽  
Maciej S. Wróbel ◽  
Katarzyna Karpienko

Due to the increasing popularity of tattoos among the general population, to ensure their safety and quality, there is a need to develop reliable and rapid methods for the analysis of the composition of tattoo inks, both in the ink itself and in already existing tattoos. This paper presents the possibility of using Raman spectroscopy to examine tattoo inks in biological materials. We have developed optical tissue phantoms mimicking the optical scattering coefficient typical for human dermis as a substitute for an in vivo study. The material employed herein allows for mimicking the tattoo-making procedure. We investigated the effect of the scattering coefficient of the matrix in which the ink is located, as well as its chemical compositions on the spectra. Raman surface line scanning has been carried out for each ink in the skin phantom to establish the spatial gradient of ink concentration distribution. This ensures the ability to detect miniature concentrations for a tattoo margin assessment. An analysis and comparison of the spectra of the inks and the tattooed inks in the phantoms are presented. We recommend the utilization of Raman spectroscopy as a screening method to enforce the tattoo ink safety legislations as well as an early medical diagnostic screening tool.


2018 ◽  
Vol 187 (2) ◽  
pp. 596-601 ◽  
Author(s):  
Marta Manso ◽  
Sofia Pessanha ◽  
Mauro Guerra ◽  
Uwe Reinholz ◽  
Cláudia Afonso ◽  
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2005 ◽  
Vol 126 ◽  
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L. Hennet ◽  
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Author(s):  
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Keyword(s):  

1981 ◽  
Vol 42 (C6) ◽  
pp. C6-776-C6-778
Author(s):  
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A. Fontana ◽  
G. Mariotto ◽  
F. Rocca ◽  
M. P. Fontana

1983 ◽  
Vol 44 (C10) ◽  
pp. C10-501-C10-503 ◽  
Author(s):  
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J. F. Rabolt

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