Assessing the connective tissue of the human tympanic membrane by PSOCT-based local retardation imaging

2021 ◽  
Author(s):  
Svea Steuer ◽  
Jonas Golde ◽  
Steffen Oßmann ◽  
Lars Kirsten ◽  
Joseph Morgenstern ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Tympanic Membrane ◽  
Human Tympanic Membrane

scholarly journals Imaging birefringent tissue in the human tympanic membrane by polarization-sensitive optical coherence tomography

2020 ◽  
Vol 238 ◽  
pp. 04008
Author(s):  
Svea Steuer ◽  
Jonas Golde ◽  
Steffen Ossmann ◽  
Lars Kirsten ◽  
Joseph Morgenstern ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Optical Coherence Tomography ◽  
Connective Tissue ◽  
Tympanic Membrane ◽  
Imaging Technique ◽  
Diagnostic Methods ◽  
Middle Ear Surgery ◽  
Optical Coherence ◽  
Ear Surgery ◽  
Human Tympanic Membrane

Acousto-mechanical properties of the human tympanic membrane mainly depend on the connective tissue in its layered structure. Using polarization-sensitive optical coherence tomography, a depth-resolved imaging technique which provides additional tissue specific contrast, polarization changes of the birefringent layers in the human tympanic membrane were detected. By depicting estimated local retardances, distinguishing different tissue types was possible. This suggests the ability to image pathological alterations of the connective tissue with PSOCT, which extends the conventional diagnostic methods in middle ear surgery.

Viscoelastic Properties of Human Tympanic Membrane

2006 ◽  
Vol 35 (2) ◽  
pp. 305-314 ◽  
Author(s):  
Tao Cheng ◽  
Chenkai Dai ◽  
Rong Z. Gan
Keyword(s):  
Tympanic Membrane ◽  
Viscoelastic Properties ◽  
Human Tympanic Membrane

Mapping the Young's modulus distribution of the human tympanic membrane by microindentation

2019 ◽  
Vol 378 ◽  
pp. 75-91 ◽  
Author(s):  
Huiyang Luo ◽  
Fang Wang ◽  
Chen Cheng ◽  
Don U. Nakmali ◽  
Rong Z. Gan ◽  
...  
Keyword(s):  
Tympanic Membrane ◽  
Young’S Modulus ◽  
Young's Modulus ◽  
Human Tympanic Membrane

scholarly journals Application of Multispectral Imaging in the Human Tympanic Membrane

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Tien Tran Van ◽  
Mi Lu Thi Thao ◽  
Linh Bui Mai Quynh ◽  
Cat Phan Ngoc Khuong ◽  
Linh Huynh Quang
Keyword(s):  
Tympanic Membrane ◽  
Middle Ear ◽  
Multispectral Imaging ◽  
Biological Tissues ◽  
Image Features ◽  
Surrounding Tissue ◽  
Surrounding Area ◽  
Boundary Determination ◽  
Intensity Images ◽  
Human Tympanic Membrane

Multispectral imaging has recently shown good performance in determining information about physiology, morphology, and composition of tissue. In the endoscopy field, many researches have shown the ability to apply multispectral or narrow-band images in surveying vascular structure based on the interaction of light wavelength with tissue composition. However, there has been no mention to assess the contrast between other components in the middle ear such as the tympanic membrane, malleus, and the surrounding area. Using CT, OCT, or ODT can clearly describe the tympanic membrane structure; nevertheless, these approaches are expensive, more complex, and time-consuming and are not suitable for most common middle ear diagnoses. Here, we show the potential of using the multispectral imaging technique to enhance the contrast of the tympanic membrane compared to the surrounding tissue. The optical absorption and scattering of biological tissues constituents are not the same at different wavelengths. In this pilot study, multiwavelength images of the tympanic membrane were captured by using the otoscope with LED light source at three distinct spectral regions: 450 nm, 530 nm, and 630 nm. Subsequently, analyses of the intensity images as well as the histogram of these images point out that the 630 nm illumination image features an evident contrast in the intensity of the tympanic membrane and malleus compared to the surrounding area. Analysis of such images could facilitate the boundary determination and segmentation of the tympanic membrane (TM) with high precision.

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