Analysis of the metabolic and oxygen status of 3D neurospheres from iPSCs using FLIM / PLIM methods

2021 ◽  
Author(s):  
Alena Kashirina ◽  
Ekaterina D. Momotyuk ◽  
Evgeniya Bukina ◽  
Erdem B. Dashinimaev ◽  
Ekaterina A. Vorotelyak ◽  
...  
Keyword(s):  
Oxygen Status

scholarly journals Analytical complex for study of the oxygen status of tissues of the human organism

2020 ◽  
Vol 1695 ◽  
pp. 012065
Author(s):  
M S Mazing ◽  
A Yu Zaitceva ◽  
Yu Ya Kislyakov ◽  
V V Davydov ◽  
N S Kondakov ◽  
...  
Keyword(s):  
Human Organism ◽  
Oxygen Status

scholarly journals Correlation between arterial and venous blood gas analysis parameters in patients with acute exacerbation of chronic obstructive pulmonary disease

2012 ◽  
Vol 140 (7-8) ◽  
pp. 436-440 ◽  
Author(s):  
Milos Novovic ◽  
Vesna Topic
Keyword(s):  
Acute Exacerbation ◽  
Venous Blood ◽  
Chronic Obstructive ◽  
Blood Gas ◽  
Obstructive Pulmonary Disease ◽  
Acute Exacerbation Of Copd ◽  
Arterial Blood ◽  
Exacerbation Of Copd ◽  
Venous Blood Gas ◽  
Oxygen Status

Introduction. Arterial blood gas (ABG) analyses have an important role in the assessment and monitoring of the metabolic and oxygen status of patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). Arterial puncture could have a lot of adverse effects, while sampling of venous blood is simpler and is not so invasive. Objective. The aim of this study was to evaluate whether venous blood gas (VBG) values of pH, partial pressure of carbon dioxide (PCO2), partial oxygen pressure (PO2), bicarbonate (HCO3), and venous and arterial blood oxygen saturation (SO2) can reliably predict ABG levels in patients with acute exacerbation of COPD. Methods. Forty-seven patients with a prior diagnosis of COPD were included in this prospective study. The patients with acute exacerbation of this disease were examined at the General Hospital EMS Department in Prijepolje. ABG samples were taken immediately after venous sampling, and both were analyzed. Results. The Pearson correlation coefficients between arterial and venous parameters were 0.828, 0.877, 0.599, 0.896 and 0.312 for pH, PCO2, PO2, HCO3 and SO2, respectively. The statistically significant correlation between arterial and venous pH, PCO2 and HCO3, values was found in patients with acute exacerbation of COPD (p<0.001). Conclusion. When we cannot provide arterial blood for analysis, venous values of the pH, Pv,CO2 and HCO3 parameters can be an alternative to their arterial equivalents in the interpretation of the metabolic status in patients with acute exacerbation of COPD, while the values of venous Pv,O2 and Sv,O2 cannot be used as predictors in the assessment of oxygen status of such patients.

2029 Noninvasive detection of tumour's oxygen status using diffuse optical tomography

2009 ◽  
Vol 7 (2) ◽  
pp. 160
Author(s):  
A. Maslennikova ◽  
A. Orlova ◽  
G. Golubjatnikov ◽  
V. Kamensky ◽  
V. Plekhanov ◽  
...  
Keyword(s):  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Noninvasive Detection ◽  
Oxygen Status

scholarly journals Immunologic Consequences of Hypoxia during Critical Illness

2016 ◽  
Vol 125 (1) ◽  
pp. 237-249 ◽  
Author(s):  
Harmke D. Kiers ◽  
Gert-Jan Scheffer ◽  
Johannes G. van der Hoeven ◽  
Holger K. Eltzschig ◽  
Peter Pickkers ◽  
...  
Keyword(s):  
Immune Responses ◽  
Signaling Pathways ◽  
Daily Practice ◽  
Innate Immune ◽  
Protective Effects ◽  
Innate Immune Responses ◽  
Downstream Signaling ◽  
Pathogen Clearance ◽  
Pharmacologic Modulation ◽  
Oxygen Status

Abstract Hypoxia and immunity are highly intertwined at clinical, cellular, and molecular levels. The prevention of tissue hypoxia and modulation of systemic inflammation are cornerstones of daily practice in the intensive care unit. Potentially, immunologic effects of hypoxia may contribute to outcome and represent possible therapeutic targets. Hypoxia and activation of downstream signaling pathways result in enhanced innate immune responses, aimed to augment pathogen clearance. On the other hand, hypoxia also exerts antiinflammatory and tissue-protective effects in lymphocytes and other tissues. Although human data on the net immunologic effects of hypoxia and pharmacologic modulation of downstream pathways are limited, preclinical data support the concept of tailoring the immune response through modulation of the oxygen status or pharmacologic modulation of hypoxia-signaling pathways in critically ill patients.

A field versus laboratory study of blood oxygen status in normoxic crabs at different temperatures

1996 ◽  
Vol 74 (3) ◽  
pp. 423-430 ◽  
Author(s):  
J.-C. Massabuau ◽  
J. Forgue
Keyword(s):  
Wide Spectrum ◽  
Venous Blood ◽  
Carcinus Maenas ◽  
Blood Oxygen ◽  
Arterial Blood ◽  
Field Versus ◽  
Partial Pressures ◽  
Different Temperatures ◽  
Head Pressure ◽  
Oxygen Status

The blood oxygen status of two species of active crabs (Carcinus maenas and Necora puber) was studied in the field and compared with the results of previous laboratory experiments performed on a wide spectrum of physiologically different water-breathers. The aim was to determine whether, as in the laboratory, the functioning of the O2 supply system in the field could be based on maintaining the arterial [Formula: see text] in the low range, 1–3 kPa. The O2 partial pressures and concentrations in the arterial and venous blood, arterial blood pH, and blood respiratory pigment concentration were measured in normoxic water at various temperatures ranging from 10 to 20 °C and in various seasons. In the field, [Formula: see text] values in normoxic C. maenas and N. puber were in the low range, 1–3 kPa, independently of temperature, season, and blood haemocyanin concentration. It is concluded that in the field as in the laboratory, [Formula: see text] values mainly in the low range provide a head pressure sufficient to meet O2 needs. The changes that appear to occur in other respiratory variables are discussed in relation to field versus laboratory conditions and temperature differences. The consequences for analysing problems of hypoxaemia in hypoxic waters or situations are discussed.

The oxygen status of fetal blood

1995 ◽  
Vol 39 ◽  
pp. 129-135 ◽  
Author(s):  
O. SIGGAARD-ANDERSEN ◽  
R. HUCH
Keyword(s):  
Fetal Blood ◽  
Oxygen Status

Oxygen status during haemodialysis

1995 ◽  
Vol 39 ◽  
pp. 195-200 ◽  
Author(s):  
A. L. NIELSEN ◽  
H. AE. JENSEN ◽  
J. HEGBRANT ◽  
H. BRINKENFELDT ◽  
P. THUNEDBORG ◽  
...  
Keyword(s):  
Oxygen Status
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