Azimuthally invariant Mueller-matrix microscopy in the differential diagnosis of cerebral infarction

2020 ◽  
Author(s):  
M. Garazdyuk ◽  
I. Savka ◽  
YUriy Tomka ◽  
I. Soltys ◽  
Olexander V. Dubolazov ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Cerebral Infarction ◽  
Mueller Matrix

scholarly journals Mueller-matrix differential diagnosis of biological crystallites phase anisotropy

2013 ◽  
Author(s):  
V. O. Ushenko ◽  
G. D. Koval ◽  
V. T. Bachinskiy ◽  
L. Ya. Kushnerick ◽  
M. Garazdiyk ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Mueller Matrix ◽  
Phase Anisotropy ◽  
Matrix Differential

scholarly journals Polarization-Singular Approach to Imaging Mueller-Matrix Polarimetry in the Differential Diagnosis of Histological Sections of Biopsy of Tumors of the Uterus and Prostate

2021 ◽  
Vol 9 ◽  
Author(s):  
A. Dubolazov ◽  
V. Ushenko ◽  
L. Trifonyuk ◽  
A. Stashkevich ◽  
I. Soltys ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Mueller Matrix ◽  
Evidence Based ◽  
Malignant Tumours ◽  
Diagnostic Use ◽  
Matrix Mapping ◽  
Adenocarcinoma Of The Prostate ◽  
Characteristic Values ◽  
Sensitivity Specificity ◽  
Based Medicine

The possibilities of the diagnostic use of the singular approach of the distributions of the number of characteristic values of the MMI is effective for differentiating the polarization properties of histological biopsy sections of benign and malignant tumours of the uterus and prostate. Within the framework of evidence-based medicine, the sensitivity, specificity and accuracy of the azimuthal-invariant express (∼15 min) method of Mueller-matrix mapping of polarization-singular states in the differential diagnosis of uterine myoma and adenocarcinoma, as well as adenocarcinoma of the prostate with varying degrees of differentiation have been determined.

Mueller-matrix mapping of biological tissues in differential diagnosis of optical anisotropy mechanisms of protein networks

2015 ◽  
Vol 45 (3) ◽  
pp. 265-269 ◽  
Author(s):  
V A Ushenko ◽  
M I Sidor ◽  
Yu F Marchuk ◽  
N V Pashkovskaya ◽  
D R Andreichuk
Keyword(s):  
Differential Diagnosis ◽  
Optical Anisotropy ◽  
Biological Tissues ◽  
Mueller Matrix ◽  
Protein Networks ◽  
Matrix Mapping

Differential diagnosis of cerebral infarction using an algorithm combining atrial fibrillation and D-dimer level

2008 ◽  
Vol 15 (3) ◽  
pp. 295-300 ◽  
Author(s):  
N. Dougu ◽  
S. Takashima ◽  
E. Sasahara ◽  
Y. Taguchi ◽  
S. Toyoda ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Differential Diagnosis ◽  
Cerebral Infarction ◽  
D Dimer

scholarly journals TO DEVELOP FORENSIC CRITERIA FOR THE DIFFERENTIAL DIAGNOSIS OF INTRACEREBRAL HEMORRHAGE OF TRAUMATIC AND NON-TRAUMATIC ORIGIN USING MUELLER-MATRIX MICROSCOPY OF LINEAR DICHROISM

2021 ◽  
Vol 2 ◽  
pp. 21-24
Author(s):  
Marta Garazdiuk ◽  
Viktor Bachynskyі ◽  
Olena Nechytailo ◽  
Oleksandr Garazdiuk
Keyword(s):  
Differential Diagnosis ◽  
Intracerebral Hemorrhage ◽  
Causes Of Death ◽  
Brain Infarction ◽  
Linear Dichroism ◽  
Mueller Matrix ◽  
Ischemic Brain ◽  
Satisfactory Level ◽  
Traumatic Origin ◽  
Matrix Invariants

Differential diagnosis of intracerebral hemorrhage due to traumatic and non-traumatic origin is a challenging issue, especially in the absence of visible body injuries and other signs of violence. For a forensic expert-practitioner, the main thing is objectivity, accuracy, and speed of obtaining the result, which could fully satisfy the methods of laser polarimetry in the case of differential diagnosis of hemorrhages of traumatic and non-traumatic origin in the human brain matter. The purpose: To develop forensic criteria for the differential diagnosis of intracerebral hemorrhage of traumatic and non-traumatic origin using Mueller-matrix microscopy of linear dichroism. Materials and methods: The object of the study was brain matter samples, collected in 115 corpses of both sexes aged 22 to 86 years with accurately known causes of death. The causes of death included coronary artery disease, traumatic brain hemorrhage, ischemic brain infarction, and non-traumatic brain hemorrhages. Brain matter samples have been frozen rapidly, and histological sections have been made using a freezing microtome. The slices have been evaluated using the method of azimuthal-invariant Mueller-matrix microscopy, followed by mathematical and statistical processing of the results.  Results: significant topographic heterogeneity of Mueller-matrix invariants of brain matter samples linear dichroism maps among all research groups have been found. Individual and significant variations of dispersion, asymmetry, and kurtosis magnitude have confirmed the heterogeneity of Mueller-matrix invariants. The difference of images and histograms among groups is explained by the presence of necrotic changes in the case of ischemic brain necrosis and blood cells in the brain matter samples. For the set of central statistical moments of the 1st, 3rd, and 4th orders, which characterize the distributions of circular dichroism, the method of MM-microscopy in the differentiation of samples of non-hemorrhage and hemorrhage groups reaches a satisfactory level - 78% - 84%. Conclusions: Brain matter samples Muller-matrix microscopy of linear dichroism is effective for solving diagnostic problems of forensic medicine related to evaluating the cause of death from intracerebral hemorrhage of various origins. Diagnostic efficiency of Mueller-matrix mapping of polarization manifestations of linear dichroism method for intergroup differentiation of samples of deaths from traumatic hemorrhage (Group 2) and ischemic cerebral infarction (Group 3) reaches a satisfactory level of 79 - 84%.

Radiological Differential Diagnosis of Cerebral Infarction

2013 ◽  
pp. 155-169
Author(s):  
Guillaume Saliou ◽  
Marie Théaudin ◽  
Claire Join-Lambert Vincent ◽  
Raphaëlle Souillard-Scemama
Keyword(s):  
Differential Diagnosis ◽  
Cerebral Infarction

scholarly journals Acute cerebral infarction in a patient with nodular glomerulopathy—Atypical features and differential diagnosis

2011 ◽  
Vol 27 (1) ◽  
pp. 39-44 ◽  
Author(s):  
Shih-Meng Yeh ◽  
Jia-Jung Lee ◽  
Chi-Chih Hung ◽  
Hung-Chun Chen ◽  
葉時孟 ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Cerebral Infarction ◽  
Acute Cerebral Infarction ◽  
Atypical Features

scholarly journals FORENSIC MEDICAL CRITERIA OF DIFFERENTIAL DIAGNOSIS OF ALCOHOL AND CARBON MONOXIDE POISONING BY USING AZIMUTHAL-INVARIANT POLARIZATION MUELLER-MATRIX MICROSCOPY

2021 ◽  
Vol 2 ◽  
pp. 33-40
Author(s):  
Olexandr Harazdiuk ◽  
Ihor Ivaskevich ◽  
Oleh Vanchuliak ◽  
Yuliia Sarkisova
Keyword(s):  
Carbon Monoxide ◽  
Differential Diagnosis ◽  
Cause Of Death ◽  
Human Body ◽  
Carbon Monoxide Poisoning ◽  
Biological Tissues ◽  
Mueller Matrix ◽  
Histological Sections ◽  
Common Causes ◽  
Characteristic Features

Introduction: Fatal intoxications with alcohol and carbon monoxide are the most common causes of poisoning that occur in forensic medical practice. Therefore, the differential diagnosis of these intoxications is extremely important. To solve this problem, we propose the use of the method of azimuthal-invariant polarization Mueller-matrix microscopy of histological sections of biological tissues (BT). Objectives: The purpose of the study was to establish statistically significant criteria for differentiation of the cause of death in case of alcohol poisoning (AP) and carbon monoxide poisoning (CMP) by using azimuthal-invariant polarization Mueller-matrix microscopy of polycrystalline fractions of histological sections of organs and blood films of the human body. Results: A number of characteristic features have been identified that have not been previously described and allow to objectively differentiate the cause of death in the case of AP and CMP, namely Ek – 0.95±0.045 and 1.81±0.092 in the study of histological sections of the myocardium;  Ek – 0,19±0,011 and 1,11±0,094 – polycrystalline blood films. Analysis of the obtained data revealed a good level of accuracy in the study of histological sections of the myocardium (As 85%) and polycrystalline blood films (As 88%). Conclusion: Thus, developed and tested method of azimuthal-invariant polarization Mueller-matrix microscopy allows to differentiate the cause of death in cases of AP and CMP.

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