scholarly journals Mueller-matrix differential diagnosis of biological crystallites phase anisotropy

2013 ◽  
Author(s):  
V. O. Ushenko ◽  
G. D. Koval ◽  
V. T. Bachinskiy ◽  
L. Ya. Kushnerick ◽  
M. Garazdiyk ◽  
...  
2021 ◽  
Vol 9 ◽  
Author(s):  
A. Dubolazov ◽  
V. Ushenko ◽  
L. Trifonyuk ◽  
A. Stashkevich ◽  
I. Soltys ◽  
...  

The possibilities of the diagnostic use of the singular approach of the distributions of the number of characteristic values of the MMI is effective for differentiating the polarization properties of histological biopsy sections of benign and malignant tumours of the uterus and prostate. Within the framework of evidence-based medicine, the sensitivity, specificity and accuracy of the azimuthal-invariant express (∼15 min) method of Mueller-matrix mapping of polarization-singular states in the differential diagnosis of uterine myoma and adenocarcinoma, as well as adenocarcinoma of the prostate with varying degrees of differentiation have been determined.


2012 ◽  
Vol 20 (2) ◽  
pp. 1151 ◽  
Author(s):  
Noé Ortega-Quijano ◽  
Bicher Haj-Ibrahim ◽  
Enric García-Caurel ◽  
José Luis Arce-Diego ◽  
Razvigor Ossikovski

2015 ◽  
Vol 45 (3) ◽  
pp. 265-269 ◽  
Author(s):  
V A Ushenko ◽  
M I Sidor ◽  
Yu F Marchuk ◽  
N V Pashkovskaya ◽  
D R Andreichuk

2021 ◽  
Vol 2 ◽  
pp. 21-24
Author(s):  
Marta Garazdiuk ◽  
Viktor Bachynskyі ◽  
Olena Nechytailo ◽  
Oleksandr Garazdiuk

Differential diagnosis of intracerebral hemorrhage due to traumatic and non-traumatic origin is a challenging issue, especially in the absence of visible body injuries and other signs of violence. For a forensic expert-practitioner, the main thing is objectivity, accuracy, and speed of obtaining the result, which could fully satisfy the methods of laser polarimetry in the case of differential diagnosis of hemorrhages of traumatic and non-traumatic origin in the human brain matter. The purpose: To develop forensic criteria for the differential diagnosis of intracerebral hemorrhage of traumatic and non-traumatic origin using Mueller-matrix microscopy of linear dichroism. Materials and methods: The object of the study was brain matter samples, collected in 115 corpses of both sexes aged 22 to 86 years with accurately known causes of death. The causes of death included coronary artery disease, traumatic brain hemorrhage, ischemic brain infarction, and non-traumatic brain hemorrhages. Brain matter samples have been frozen rapidly, and histological sections have been made using a freezing microtome. The slices have been evaluated using the method of azimuthal-invariant Mueller-matrix microscopy, followed by mathematical and statistical processing of the results.  Results: significant topographic heterogeneity of Mueller-matrix invariants of brain matter samples linear dichroism maps among all research groups have been found. Individual and significant variations of dispersion, asymmetry, and kurtosis magnitude have confirmed the heterogeneity of Mueller-matrix invariants. The difference of images and histograms among groups is explained by the presence of necrotic changes in the case of ischemic brain necrosis and blood cells in the brain matter samples. For the set of central statistical moments of the 1st, 3rd, and 4th orders, which characterize the distributions of circular dichroism, the method of MM-microscopy in the differentiation of samples of non-hemorrhage and hemorrhage groups reaches a satisfactory level - 78% - 84%. Conclusions: Brain matter samples Muller-matrix microscopy of linear dichroism is effective for solving diagnostic problems of forensic medicine related to evaluating the cause of death from intracerebral hemorrhage of various origins. Diagnostic efficiency of Mueller-matrix mapping of polarization manifestations of linear dichroism method for intergroup differentiation of samples of deaths from traumatic hemorrhage (Group 2) and ischemic cerebral infarction (Group 3) reaches a satisfactory level of 79 - 84%.


2021 ◽  
Vol 69 ◽  
pp. 102815
Author(s):  
Muaz Iqbal ◽  
Shamim Khan ◽  
Banat Gul ◽  
Manzoor Ahmad ◽  
Iftikhar Ahmad

2021 ◽  
Vol 2 ◽  
pp. 33-40
Author(s):  
Olexandr Harazdiuk ◽  
Ihor Ivaskevich ◽  
Oleh Vanchuliak ◽  
Yuliia Sarkisova

Introduction: Fatal intoxications with alcohol and carbon monoxide are the most common causes of poisoning that occur in forensic medical practice. Therefore, the differential diagnosis of these intoxications is extremely important. To solve this problem, we propose the use of the method of azimuthal-invariant polarization Mueller-matrix microscopy of histological sections of biological tissues (BT). Objectives: The purpose of the study was to establish statistically significant criteria for differentiation of the cause of death in case of alcohol poisoning (AP) and carbon monoxide poisoning (CMP) by using azimuthal-invariant polarization Mueller-matrix microscopy of polycrystalline fractions of histological sections of organs and blood films of the human body. Results: A number of characteristic features have been identified that have not been previously described and allow to objectively differentiate the cause of death in the case of AP and CMP, namely Ek – 0.95±0.045 and 1.81±0.092 in the study of histological sections of the myocardium;  Ek – 0,19±0,011 and 1,11±0,094 – polycrystalline blood films. Analysis of the obtained data revealed a good level of accuracy in the study of histological sections of the myocardium (As 85%) and polycrystalline blood films (As 88%). Conclusion: Thus, developed and tested method of azimuthal-invariant polarization Mueller-matrix microscopy allows to differentiate the cause of death in cases of AP and CMP.


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