scholarly journals Accurate detection of white matter tracts: mapping of human brain eloquent areas with cross-polarization optical coherence tomography

2020 ◽  
Author(s):  
Elena B. Kiseleva ◽  
Konstantin S. Yashin ◽  
Alexander A. Moiseev ◽  
Diana A. Davydova ◽  
Ksenia Achkasova ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
White Matter ◽  
Human Brain ◽  
Optical Coherence ◽  
Cross Polarization ◽  
White Matter Tracts ◽  
Eloquent Areas ◽  
Accurate Detection

scholarly journals Refractive-index matching enhanced polarization-sensitive optical coherence tomography quantification in human brain tissue

2021 ◽  
Author(s):  
Chao J. Liu ◽  
William Ammon ◽  
Robert Jones ◽  
Jackson Nolan ◽  
Ruopeng Wang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Refractive Index ◽  
White Matter ◽  
Human Brain ◽  
Brain Tissue ◽  
Gray Matter ◽  
Optical Coherence ◽  
Human Brain Tissue ◽  
Index Matching ◽  
Refractive Index Matching

The importance of polarization-sensitive optical coherence tomography (PS-OCT) has been increasingly recognized in human brain imaging. Despite the recent progress of PS-OCT in revealing white matter architecture and orientation, quantification of fine-scale fiber tracts in the human brain cortex has been a challenging problem, due to a low birefringence in the gray matter. In this study, we investigated the effect of refractive index matching by 2,2'-thiodiethanol (TDE) immersion on the improvement of PS-OCT measurements in ex vivo human brain tissue. We obtain the cortical fiber orientation maps in the gray matter, which reveals the radial fibers in the gyrus, the U-fibers along the sulcus, as well as distinct layers of fiber axes exhibiting laminar organization. Further analysis shows that index matching reduces the noise in axis orientation measurements by 56% and 39%, in white and gray matter, respectively. Index matching also enables precise measurements of apparent birefringence, which was underestimated in the white matter by 82% but overestimated in the gray matter by 16% prior to TDE immersion. Mathematical simulations show that the improvements are primarily attributed to the reduction in the tissue scattering coefficient, leading to an enhanced signal-to-noise ratio in deeper tissue regions, which could not be achieved by conventional noise reduction methods.

Impact of surface micromorphology and demineralization severity on enamel loss measurements by cross-polarization optical coherence tomography

2019 ◽  
Vol 81 ◽  
pp. 52-58 ◽  
Author(s):  
Maryam A. Alghilan ◽  
Frank Lippert ◽  
Jeffrey A. Platt ◽  
George J. Eckert ◽  
Carlos González-Cabezas ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Cross Polarization ◽  
Surface Micromorphology

scholarly journals Multicontrast endomyocardial imaging by single-channel high-resolution cross-polarization optical coherence tomography

2018 ◽  
Vol 11 (4) ◽  
pp. e201700204 ◽  
Author(s):  
Xinwen Yao ◽  
Yu Gan ◽  
Yuye Ling ◽  
Charles C. Marboe ◽  
Christine P. Hendon
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Single Channel ◽  
Optical Coherence ◽  
Cross Polarization
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