Hybrid system of different shapes of gold nanoparticles on microcavity to study Purcell’s effect

2020 ◽  
Author(s):  
Tulika Agrawal ◽  
Shubhayan Bhattacharya ◽  
Aneesh Vincent Veluthandath ◽  
Ganapathy Senthil Murugan ◽  
Gurvinder Singh ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Hybrid System ◽  
Different Shapes

Potential of rod, sphere and semi-cube shaped gold nanoparticles to induce cytotoxicity and genotoxicity in human blood lymphocytes in vitro

2015 ◽  
Vol 7 (1) ◽  
Author(s):  
Mona A.M. Abo-Zeid ◽  
Thomas Liehr ◽  
Amira M. Gamal-Eldeen ◽  
Mahmoud Zawrah ◽  
Mostafa Ali ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Gold Nanoparticles ◽  
Mitotic Activity ◽  
Human Blood ◽  
Human Peripheral Blood ◽  
Human Lymphocytes ◽  
Blood Lymphocytes ◽  
Human Blood Lymphocytes ◽  
Different Shapes

AbstractGold nanoparticles (GNPs) are intended to be used in nanomedicine. Due to nanotechnology innovation GNPs of variable sizes and in different shapes including rods, spheres, cubes, etc., can easily be produced. The aim of the present studies was to evaluate the cyto-and genotoxicity inducible by different shaped GNPs on normal human peripheral blood lymphocytes.Four different shapes of GNPs including big rod GNPs (BR-GNPs, 50 nm), small rod GNPs (SR-GNPs, 30 nm), sphere GNPs (S-GNPs, 15 nm) and semi-cube GNPs (SC-GNPs, 15 nm) were studied. Cultured human blood lymphocytes were treated with different concentrations of these GNPs for 24 h in vitro. Cytotoxicity was evaluated based on the mitotic index (MI), while genotoxicity was studied by an interphase-fluorescence in situ hybridization (I-FISH) assay. The following genes were studied in I-FISH:The lowest concentration of BR-GNPs neither had an effect mitotic activity nor enhanced gain or loss of examined gene signals in a significant manner with I-FSH. Other concentrations of BR-GNPs, SR-GNPs, S-GNPs and SC-GNPs with all concentrations inhibited the mitotic activity of the cells and reduced the cell proliferation highly significantly. The different types of GNPs initiated the duplication ofGNPs at high concentration can reduce the cell proliferation and induce DNA damage. Low concentration of rod-shaped GNPs at 50 nm was safe on human lymphocytes. Further research studies are required to optimize the concentration, shape and size of GNPs before using them in nanomedicine.

scholarly journals Assessing the effect of different shapes of glyco-gold nanoparticles on bacterial adhesion and infections

2015 ◽  
Vol 51 (86) ◽  
pp. 15669-15672 ◽  
Author(s):  
Preeti Madhukar Chaudhary ◽  
Sivakoti Sangabathuni ◽  
Raghavendra Vasudeva Murthy ◽  
Ajay Paul ◽  
Hirekodathakallu V. Thulasiram ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Bacterial Infection ◽  
Bacterial Adhesion ◽  
Different Shapes

Different shapes of glyco gold nanoparticles (AuNPs) tune the bacterial aggregations, which can effectively inhibit the bacterial infection of cells.

scholarly journals Emergence of Selectivity in Inherently Nonselective Gold Nanoparticles Through Preferential Breaking of Interparticle Interactions

2018 ◽  
Author(s):  
Anish Rao ◽  
Govind Sasi Kumar ◽  
Soumendu Roy ◽  
Ajesh T. R. ◽  
Gayathri Devatha ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Hybrid System ◽  
Stable State ◽  
Aggregation Process ◽  
Divalent Ions ◽  
Interparticle Interactions ◽  
Functionalized Gold Nanoparticles ◽  
The Common ◽  
Conventional Idea ◽  
Identification Strategy

<p>We demonstrate a fundamentally unique identification strategy to impart selectivity to a traditionally and inherently nonselective carboxylate-functionalized gold-nanoparticles ([-] AuNPs), without the aid of any analyte specific ligands. The common practice is to use the ability of divalent ions to trigger the aggregation process in a kinetically trapped dispersed solution of [-] AuNPs. Aggregation of NPs being a thermodynamically favourable process will result in a uniform and nonselective turn-off response from most of the strongly binding divalent ions. Our approach is to use the abilities of various divalent ions to break a thermodynamically stable inter-nanoparticle precipitates containing [+] and [-] AuNPs (<i>nanoionic precipitates</i>), as the means of identification. Importantly both [+] and [-] AuNPs, independently, were ‘blind’ in terms of selectivity towards divalent ions. Remarkably, a hybrid-system composed of such nonselective nanoparticles was able to discriminate between the hard-to-distinguish pair of Pb<sup>2+</sup> and Cd<sup>2+</sup> ions. The rationale is that only the strongest of strongly binding ions will be able to break the interactions between the NP precipitates (thermodynamically stable state) and re-disperse them back in solution (kinetically trapped state). This is in stark contrast with the conventional idea of forming an interaction between NPs and divalent ions, with the help of analyte-specific ligands.</p>

scholarly journals The Properties of Nano-Gold Particles Synthesized by Ascorbic Acid With Acacia Gum and Sodium Hydroxide as Stabilizers

2019 ◽  
pp. 2149-2155
Author(s):  
Dhelal Abdul Ghafoor ◽  
Rana M. Yas ◽  
Muna Ahmed Saeed
Keyword(s):  
Gold Nanoparticles ◽  
Ascorbic Acid ◽  
Sodium Hydroxide ◽  
Wave Length ◽  
Chloroauric Acid ◽  
Nano Particle ◽  
Nano Gold ◽  
Acacia Gum ◽  
Different Shapes ◽  
Uv Visible

In this work, biocompatible gold nanoparticles were synthesized by reducing the chloroauric acid with ascorbic acid as a reducing agent. Colloidal gold nanoparticles were stabilized through nontoxic acacia gum sodium hydroxide .Synthesizing gold nano particle is confirmed by the change in color of chloroauric acid from yellow to ruby red and brown color depending on the stabilizers. The gold nanoparticles were characterized by UV-Visible spectrophotometer. Where the peak of the absorbance of surface plasmon resonance (SPR) was observed between the wave length 526 and 535 nm. The results of zeta potential were found in rang (-19, -40 mv), AFM and TEM images show two different shapes, hexagonal and spherical and the size of gold nanoparticles between 21.5nm and  29nm.

scholarly journals Aqueous-Phase Catalytic Chemical Reduction of p-Nitrophenol Employing Soluble Gold Nanoparticles with Different Shapes

Catalysts ◽  
2016 ◽  
Vol 6 (12) ◽  
pp. 215 ◽  
Author(s):  
Francyelle de Oliveira ◽  
Lucas Nascimento ◽  
Claudia Calado ◽  
Mario Meneghetti ◽  
Monique da Silva
Keyword(s):  
Gold Nanoparticles ◽  
Aqueous Phase ◽  
Chemical Reduction ◽  
Different Shapes

Bioreduction of chloroaurate ions by geranium leaves and its endophytic fungus yields gold nanoparticles of different shapes

2003 ◽  
Vol 13 (7) ◽  
pp. 1822 ◽  
Author(s):  
S. Shiv Shankar ◽  
Absar Ahmad ◽  
Renu Pasricha ◽  
Murali Sastry
Keyword(s):  
Gold Nanoparticles ◽  
Endophytic Fungus ◽  
Different Shapes

scholarly journals Photostability of gold nanoparticles with different shapes: the role of Ag clusters

Nanoscale ◽  
2015 ◽  
Vol 7 (26) ◽  
pp. 11273-11279 ◽  
Author(s):  
Yasser A. Attia ◽  
David Buceta ◽  
Félix G. Requejo ◽  
Lisandro J. Giovanetti ◽  
M. Arturo López-Quintela
Keyword(s):  
Gold Nanoparticles ◽  
Low Power ◽  
Uv Irradiation ◽  
Gold Nanorods ◽  
Ag Clusters ◽  
Different Shapes

Involvement of semiconductor-like Ag clusters in the photodissolution of gold nanorods and nanoprisms by low-power UV irradiation.

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