Synergy of light and sound for high-resolution optical focusing, imaging, and stimulation through and within scattering media (Conference Presentation)

Author(s):  
Puxiang Lai ◽  
Zhipeng Yu ◽  
Huanhao Li ◽  
Tianting Zhong ◽  
Zihao Li
2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Zhipeng Yu ◽  
Jiangtao Huangfu ◽  
Fangyuan Zhao ◽  
Meiyun Xia ◽  
Xi Wu ◽  
...  

2017 ◽  
Vol 111 (22) ◽  
pp. 221109 ◽  
Author(s):  
Ashton S. Hemphill ◽  
Yuecheng Shen ◽  
Yan Liu ◽  
Lihong V. Wang

2020 ◽  
Vol 116 (24) ◽  
pp. 241104
Author(s):  
Dayan Li ◽  
Sujit Kumar Sahoo ◽  
Huy Quoc Lam ◽  
Dong Wang ◽  
Cuong Dang

2018 ◽  
Vol 57 (36) ◽  
pp. 10441 ◽  
Author(s):  
Maxim N. Cherkashin ◽  
Carsten Brenner ◽  
Martin R. Hofmann

2021 ◽  
Vol 7 (28) ◽  
pp. eaay5496
Author(s):  
Cheng Zheng ◽  
Jong Kang Park ◽  
Murat Yildirim ◽  
Josiah R. Boivin ◽  
Yi Xue ◽  
...  

Nonlinear optical microscopy has enabled in vivo deep tissue imaging on the millimeter scale. A key unmet challenge is its limited throughput especially compared to rapid wide-field modalities that are used ubiquitously in thin specimens. Wide-field imaging methods in tissue specimens have found successes in optically cleared tissues and at shallower depths, but the scattering of emission photons in thick turbid samples severely degrades image quality at the camera. To address this challenge, we introduce a novel technique called De-scattering with Excitation Patterning or “DEEP,” which uses patterned nonlinear excitation followed by computational imaging–assisted wide-field detection. Multiphoton temporal focusing allows high-resolution excitation patterns to be projected deep inside specimen at multiple scattering lengths due to the use of long wavelength light. Computational reconstruction allows high-resolution structural features to be reconstructed from tens to hundreds of DEEP images instead of millions of point-scanning measurements.


2021 ◽  
Vol 60 (03) ◽  
Author(s):  
Shenghang Zhou ◽  
Xiubao Sui ◽  
Wenhui Zhang ◽  
Yingzi Hua ◽  
Qian Chen ◽  
...  

2015 ◽  
Vol 35 (2) ◽  
pp. 0211006
Author(s):  
文政博 Wen Zhengbo ◽  
吴雨霖 Wu Yulin ◽  
张秀达 Zhang Xiuda ◽  
严惠民 Yan Huimin ◽  
魏少鹏 Wei Shaopeng

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