Methodological considerations regarding the problem of apparent versus intrinsic fluorescence properties of historical paint layers (Conference Presentation)

Author(s):  
Fabien Pottier ◽  
Anne Michelin ◽  
Christine Andraud ◽  
Fabrice Goubard ◽  
Bertrand Lavédrine
Biochemistry ◽  
2008 ◽  
Vol 47 (46) ◽  
pp. 12159-12174 ◽  
Author(s):  
Cédric Montigny ◽  
Bertrand Arnou ◽  
Estelle Marchal ◽  
Philippe Champeil

2013 ◽  
Vol 15 (21) ◽  
pp. 8162 ◽  
Author(s):  
Jean-François Greisch ◽  
Michael E. Harding ◽  
Mattias Kordel ◽  
Wim Klopper ◽  
Manfred M. Kappes ◽  
...  

1996 ◽  
Vol 271 (44) ◽  
pp. 27249-27258 ◽  
Author(s):  
Paolo Neyroz ◽  
Carolina Menna ◽  
Eugenia Polverini ◽  
Lanfranco Masotti

2020 ◽  
Vol 18 (42) ◽  
pp. 8668-8676
Author(s):  
Constance M. Korkor ◽  
Larnelle F. Garnie ◽  
Leah Amod ◽  
Timothy J. Egan ◽  
Kelly Chibale

Intrinsic fluorescence properties, docking and a hemozoin inhibition assay were employed to study the mechanism of action of two structurally related pyrido-[1,2-a]benzimidazole derivatives.


2014 ◽  
Vol 43 (2) ◽  
pp. 246-248 ◽  
Author(s):  
Lei Cao ◽  
Dandan Jia ◽  
Shaofei Wang ◽  
Yunlong Rong ◽  
Chun Liu ◽  
...  

2006 ◽  
Vol 61 (9-10) ◽  
pp. 741-748 ◽  
Author(s):  
Michael U. Kumke ◽  
Carsten Dosche ◽  
Roman Flehr ◽  
Wolfram Trowitzsch-Kienast ◽  
Hans-Gerd Löhmannsröben

AbstractSiderophores play a very important role in the uptake process of iron by bacteria. Due to the so-called active transport the uptake of siderophores by bacteria is very specific, which makes the use of siderophores as effective shuttles for antibiotics in the treatment of infections and other diseases caused by bacteria highly attractive. In order to further investigate the transport and incorporation of siderophores into the bacteria cells, distinct molecular probes are needed. Especially artificial siderophores, that show a specific intrinsic fluorescence, are highly attractive for such monitoring purposes. A promising candidate of such a fluorescent artificial siderophore is bis-2,3-dihydroxybenzoyl-2,6-dimethylamino-pyridine (pyridinochelin, PY). The fluorescence properties of PY were investigated in different solvents and in the presence of different metal ions. It was found that PY in its free form shows a complex fluorescence behavior. In methanol a clear dual fluorescence is observed. In aqueous solution intermolecular interactions with water molecules are determining the intrinsic fluorescence. Upon complexation with metal ions (Me3+ = Eu3+, Tb3+, Al3+, Fe3+) the fluorescence characteristics changed. The fluorescence quantum yield of PY decreased upon addition of Me3+ - except for Al3+, which showed no fluorescence quenching. The fluorescence decay of PY loaded with metal ions showed a nicely mono-exponential fluorescence decay, which was in contrast to PY in the absence of metal ions. This drastic change in the fluorescence properties of PY upon metal ion complexation makes PY highly attractive as a fluorescence probe for the investigation of siderophore action and siderophore-mediated transport processes


2010 ◽  
Vol 24 (3) ◽  
pp. 173-185 ◽  
Author(s):  
Martin Krippl ◽  
Stephanie Ast-Scheitenberger ◽  
Ina Bovenschen ◽  
Gottfried Spangler

In light of Lang’s differentiation of the aversive and the approach system – and assumptions stemming from attachment theory – this study investigates the role of the approach or caregiving system for processing infant emotional stimuli by comparing IAPS pictures, infant pictures, and videos. IAPS pictures, infant pictures, and infant videos of positive, neutral, or negative content were presented to 69 mothers, accompanied by randomized startle probes. The assessment of emotional responses included subjective ratings of valence and arousal, corrugator activity, the startle amplitude, and electrodermal activity. In line with Lang’s original conception, the typical startle response pattern was found for IAPS pictures, whereas no startle modulation was observed for infant pictures. Moreover, the startle amplitudes during negative video scenes depicting crying infants were reduced. The results are discussed with respect to several theoretical and methodological considerations, including Lang’s theory, emotion regulation, opponent process theory, and the parental caregiving system.


2020 ◽  
Vol 25 (1) ◽  
pp. 1-15 ◽  
Author(s):  
Amaia Del Campo ◽  
Marisalva Fávero

Abstract. During the last decades, several studies have been conducted on the effectiveness of sexual abuse prevention programs implemented in different countries. In this article, we present a review of 70 studies (1981–2017) evaluating prevention programs, conducted mostly in the United States and Canada, although with a considerable presence also in other countries, such as New Zealand and the United Kingdom. The results of these studies, in general, are very promising and encourage us to continue this type of intervention, almost unanimously confirming its effectiveness. Prevention programs encourage children and adolescents to report the abuse experienced and they may help to reduce the trauma of sexual abuse if there are victims among the participants. We also found that some evaluations have not considered the possible negative effects of this type of programs in the event that they are applied inappropriately. Finally, we present some methodological considerations as critical analysis to this type of evaluations.


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